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Quantification of Lignans in Food Using Isotope Dilution Gas Chromatography/Mass Spectrometry
Abstract
The optimization and validation of a protocol for the quantification of six dietary lignans, i.e., secoisolariciresinol, matairesinol, lariciresinol, pinoresinol, medioresinol, and syringaresinol, in food are presented. The method incorporates isotope dilution to ensure correct accuracy and precision, introducing the utilization of individual stable 13C3-labeled lignans. To demonstrate the potential of this new method, preliminary results of the levels of dietary lignans in selected foods are presented. It is concluded that the method fulfils the reliability criteria and can be applied to the analysis of the most common lignans in human food, being an essential asset to establish the intake of lignans in a determined population and their relation with disease prevention.
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Cited by
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Interaction between Phenolics and Gut Microbiota: Role in Human Health
Selma, M. V., Espín, J. C., & Tomás-Barberán, F. A. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf902107d · Cited by 1,324
Polyphenols: A concise overview on the chemistry, occurrence, and human health
Durazzo, A., Lucarini, M., Souto, E. B., Cicala, C., Caiazzo, E., Izzo, A. A., Novellino, E., & Santini, A. (2019) · Phytotherapy Research · doi:10.1002/ptr.6419 · Cited by 802
The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism
Spanogiannopoulos, P., Bess, E. N., Carmody, R. N., & Turnbaugh, P. J. (2016) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.17 · Cited by 717
Quantification of a Broad Spectrum of Lignans in Cereals, Oilseeds, and Nuts
Smeds, A. I., Eklund, P. C., Sjöholm, R. E., Willför, S. M., Nishibe, S., Deyama, T., & Holmbom, B. R. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0629134 · Cited by 306
Metadata
- Authors
- Peñalvo, J. L., Haajanen, K. M., Botting, N., & Adlercreutz, H.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-10-26
- Volume
- 53
- Issue
- 24
- Pages
- 9342-9347
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2060612800
- Cited by
- 198
- References
- 0
- FWCI
- 3.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- Peñalvo, J. L., Haajanen, K. M., Botting, N., & Adlercreutz, H. (2005). Quantification of Lignans in Food Using Isotope Dilution Gas Chromatography/Mass Spectrometry. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf051488w
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