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Insecticidal and Genotoxic Activities of Oregano Essential Oils
Abstract
The essential oils (EOs) obtained from the oregano plants Origanum vulgare subsp. hirtum, Coridothymus capitatus, and Satureja thymbra were examined by a combination of GC and GC−MS and found to be rich in carvacrol, thymol, γ-terpinene, and p -cymene. These EOs and their main constituents, carvacrol and thymol, were tested for insecticidal and genotoxic activities on Drosophila . The EO of S. thymbra was found to be the most effective as an insecticide, while carvacrol was found to be more toxic than thymol. The toxicities of carvacrol and thymol do not correspond to their participation in the EOs, and mixtures of these two phenols in levels resembling their content in the three oils showed that the toxicity of carvacrol was reduced in the presence of thymol, thus suggesting antagonistic phenomena. The somatic mutation and recombination test on Drosophila revealed that, among the five compounds studied, only thymol exhibits genotoxic activity. Keywords: Oregano; Origanum vulgare; Coridothymus capitatus; Satureja thymbra; essential oils; carvacrol; thymol; insecticides; genotoxicity; Drosophila melanogaster
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Cited by
Essential oils: Their antibacterial properties and potential applications in foods—A review
Burt, S. (2004) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2004.03.022 · Cited by 10,488
Biological effects of essential oils—A review
Bakkali, F., Averbeck, S., Averbeck, D., & Idaomar, M. (2008) · Food and Chemical Toxicology · doi:10.1016/j.fct.2007.09.106 · Cited by 7,929
Antibacterial and antifungal activities of thymol: A brief review of the literature
Marchese, A., Orhan, I. E., Daglia, M., Barbieri, R., Di Lorenzo, A., Nabavi, S. F., Gortzi, O., Izadi, M., & Nabavi, S. M. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.04.111 · Cited by 913
Teixeira, B., Marques, A., Ramos, C., Serrano, C., Matos, O., Neng, N. R., Nogueira, J. M. F., Saraiva, J. A., & Nunes, M. L. (2013) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.6089 · Cited by 311
Essential oils as multicomponent mixtures and their potential for human health and well-being
Bunse, M., Daniels, R., Gründemann, C., Heilmann, J., Kammerer, D. R., Keusgen, M., Lindequist, U., Melzig, M. F., Morlock, G. E., Schulz, H., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.956541 · Cited by 210
Metadata
- Authors
- Karpouhtsis, I., Pardali, E., Feggou, E., Kokkini, S., Scouras, Z. G., & Mavragani-Tsipidou, P.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 1998-02-24
- Volume
- 46
- Issue
- 3
- Pages
- 1111-1115
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W4236904001
- Cited by
- 190
- References
- 0
- FWCI
- 2.40
- Type
- journal article
- Language
- en
- Open access
- closed
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- Karpouhtsis, I., Pardali, E., Feggou, E., Kokkini, S., Scouras, Z. G., & Mavragani-Tsipidou, P. (1998). Insecticidal and Genotoxic Activities of Oregano Essential Oils. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf970822o
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