The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Covalent Modifiers: An Orthogonal Approach to Drug Design
Abstract
ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTCovalent Modifiers: An Orthogonal Approach to Drug DesignMichele H. Potashman* and Mark E. Duggan*§View Author Information Department of Medicinal Chemistry, Amgen Inc., One Kendall Square, Building 1000, Cambridge, Massachusetts 02139* To whom correspondence should be addressed. For M.H.P.: phone, (617) 444-5010; fax, (617) 577-9288; e-mail, [email protected]. For M.E.D.: phone, (617) 583-1983; e-mail, [email protected]§Current address: Link Medicine Inc., 161 First Street, Cambridge, MA 02142.Cite this: J. Med. Chem. 2009, 52, 5, 1231–1246Publication Date (Web):February 9, 2009Publication History Received11 July 2008Published online9 February 2009Published inissue 12 March 2009https://pubs.acs.org/doi/10.1021/jm8008597https://doi.org/10.1021/jm8008597review-articleACS PublicationsCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views16521Altmetric-Citations288LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Adducts,Inhibition,Inhibitors,Monomers,Peptides and proteins Get e-Alerts
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Citations
Cites
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
Yun, C.-H., Mengwasser, K. E., Toms, A. V., Woo, M. S., Greulich, H., Wong, K.-K., Meyerson, M., & Eck, M. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709662105 · Cited by 2,118
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
Powers, J. C., Asgian, J. L., Ekici, Ö. D., & James, K. E. (2002) · Chemical Reviews · doi:10.1021/cr010182v · Cited by 1,090
Why Drugs Fail - A Study on Side Effects in New Chemical Entities
Schuster, D., Laggner, C., & Langer, T. (2005) · Current Pharmaceutical Design · doi:10.2174/138161205774414510 · Cited by 417
Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective
Park, B. K., Pirmohamed, M., & Kitteringham, N. R. (1998) · Chemical Research in Toxicology · doi:10.1021/tx980058f · Cited by 267
Pharmacodynamics: Relation to Antimicrobial Resistance
Rybak, M. J. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2006.04.001 · Cited by 120
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The resurgence of covalent drugs
Singh, J., Petter, R. C., Baillie, T. A., & Whitty, A. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3410 · Cited by 1,873
Jackson, P. A., Widen, J. C., Harki, D. A., & Brummond, K. M. (2017) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6b00788 · Cited by 588
Targeted Covalent Inhibitors for Drug Design
Baillie, T. A. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201601091 · Cited by 578
Bauer, R. A. (2015) · Drug Discovery Today · doi:10.1016/j.drudis.2015.05.005 · Cited by 534
A Perspective on the Kinetics of Covalent and Irreversible Inhibition
Strelow, J. M. (2017) · SLAS Discovery · doi:10.1177/1087057116671509 · Cited by 392
Metadata
- Authors
- Potashman, M. H., & Duggan, M. E.
- Venue
- Journal of Medicinal Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-02-09
- Volume
- 52
- Issue
- 5
- Pages
- 1231-1246
- ISSN
- 0022-2623 (ISSN-L)
- 1520-4804
- OpenAlex
- W2078585784
- Cited by
- 346
- References
- 5
- FWCI
- 12.61
- Type
- journal article
- Language
- en
- Open access
- closed
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