Thiosemicarbazones from the Old to New: Iron Chelators That Are More Than Just Ribonucleotide Reductase Inhibitors

Abstract

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTThiosemicarbazones from the Old to New: Iron Chelators That Are More Than Just Ribonucleotide Reductase InhibitorsYu Yu†‡, Danuta S. Kalinowski†‡, Zaklina Kovacevic†, Aritee R. Siafakas†, Patric J. Jansson†, Christian Stefani†, David B. Lovejoy†, Philip C. Sharpe§, Paul V. Bernhardt§, and Des R. Richardson*†View Author Information† Department of Pathology and Bosch Institute, Blackburn Building (D06), University of Sydney, Sydney, New South Wales 2006, Australia§ Centre for Metals in Biology, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, QLD 4072, Australia*To whom correspondence should be addressed. Phone: +61-2-9036-6548. Fax: +61-2-9351-3429. E-mail: [email protected]‡Contributed equally to this submission.Cite this: J. Med. Chem. 2009, 52, 17, 5271–5294Publication Date (Web):July 14, 2009Publication History Received30 April 2009Published online14 July 2009Published inissue 10 September 2009https://pubs.acs.org/doi/10.1021/jm900552rhttps://doi.org/10.1021/jm900552rreview-articleACS PublicationsCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views5171Altmetric-Citations319LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Cells,Ligands,Mechanisms of action,Redox reactions,Toxicity Get e-Alerts