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Protease Inhibitors: Current Status and Future Prospects
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ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTProtease Inhibitors: Current Status and Future ProspectsDonmienne Leung, Giovanni Abbenante, and David P. FairlieView Author Information Centre for Drug Design and Development, University of Queensland, Brisbane, Queensland 4072, Australia Cite this: J. Med. Chem. 2000, 43, 3, 305–341Publication Date (Web):February 10, 2000Publication History Received12 August 1999Published online10 February 2000Published inissue 1 February 2000https://pubs.acs.org/doi/10.1021/jm990412mhttps://doi.org/10.1021/jm990412mreview-articleACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views9760Altmetric-Citations748LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anatomy,Inhibitors,Monomers,Peptides and proteins,Reaction products Get e-Alerts
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Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., Teplow, D. B., Ross, S., Amarante, P., Loeloff, R., et al. (1999) · Science · doi:10.1126/science.286.5440.735 · Cited by 3,876
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
Black, R. A., Rauch, C. T., Kozlosky, C. J., Peschon, J. J., Slack, J. L., Wolfson, M. F., Castner, B. J., Stocking, K. L., Reddy, P., Srinivasan, S., et al. (1997) · Nature · doi:10.1038/385729a0 · Cited by 3,149
ONO-5046, a novel inhibitor of human neutrophil elastase
Kawabata, K., Suzuki, M., Sugitani, M., Imaki, K., Toda, M., & Miyamoto, T. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)91862-7 · Cited by 359
In Vivo Analysis of Secreted Aspartyl Proteinase Expression in Human Oral Candidiasis
Naglik, J. R., Newport, G., White, T. C., Fernandes-Naglik, L. L., Greenspan, J. S., Greenspan, D., Sweet, S. P., Challacombe, S. J., & Agabian, N. (1999) · Infection and Immunity · doi:10.1128/iai.67.5.2482-2490.1999 · Cited by 193
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Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
Powers, J. C., Asgian, J. L., Ekici, Ö. D., & James, K. E. (2002) · Chemical Reviews · doi:10.1021/cr010182v · Cited by 1,090
High-throughput screening assays for the identification of chemical probes
Inglese, J., Johnson, R. L., Simeonov, A., Xia, M., Zheng, W., Austin, C. P., & Auld, D. S. (2007) · Nature Chemical Biology · doi:10.1038/nchembio.2007.17 · Cited by 614
A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
Ratia, K., Pegan, S., Takayama, J., Sleeman, K., Coughlin, M., Baliji, S., Chaudhuri, R., Fu, W., Prabhakar, B. S., Johnson, M. E., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805240105 · Cited by 507
Profiling Serine Hydrolase Activities in Complex Proteomes
Kidd, D., Liu, Y., & Cravatt, B. F. (2001) · Biochemistry · doi:10.1021/bi002579j · Cited by 368
Stachel, S. J., Coburn, C. A., Steele, T. G., Jones, K. G., Loutzenhiser, E. F., Gregro, A. R., Rajapakse, H. A., Lai, M.-T., Crouthamel, M.-C., Xu, M., et al. (2004) · Journal of Medicinal Chemistry · doi:10.1021/jm049379g · Cited by 262
Metadata
- Authors
- Leung, D., Abbenante, G., & Fairlie, D. P.
- Venue
- Journal of Medicinal Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2000-02-01
- Volume
- 43
- Issue
- 3
- Pages
- 305-341
- ISSN
- 0022-2623 (ISSN-L)
- 1520-4804
- OpenAlex
- W2062253359
- Cited by
- 883
- References
- 4
- FWCI
- 24.96
- Type
- journal article
- Language
- en
- Open access
- green
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