Esterification in Ionic Liquids: The Influence of Solvent Basicity
Abstract
The second-order rate constant (k2) for the esterification of methoxyacetic acid with benzyl alcohol is reported in a range of ionic and molecular solvents. The solvent effects on esterification rate are examined by using a linear solvation energy relationship based on the Kamlet-Taft solvent scales (alpha, beta, and pi*). It is shown that the hydrogen bond basicity of the solvent is the dominant parameter in determining the esterification rate and that the best rates are achieved in low basicity solvents.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Decomposition of [C2C1im][MeCO2] and [C2C1im]Cl at 100-130 °C was almost complete within 4 months.
“Decomposition of [C 2 C 1 im]-[MeCO 2 ] and [C 2 C 1 im]Cl at 100-130 °C was almost complete within 4 months.177”
From Deconstruction of lignocellulosic biomass with ionic liquids (2013) · cites this paper as [177]
Cites
Room-Temperature Ionic Liquids: Solvents for Synthesis and Catalysis. 2
Hallett, J. P., & Welton, T. (2011) · Chemical Reviews · doi:10.1021/cr1003248 · Cited by 12,581 · see citing works
Self-citationRoom-Temperature Ionic Liquids. Solvents for Synthesis and Catalysis
Welton, T. (1999) · Chemical Reviews · doi:10.1021/cr980032t · Cited by 11,866 · see citing works
Self-citationGreen Chemistry: Theory and Practice
Anastas, P. T., & Warner, J. C. (1998) · Medical Entomology and Zoology · Cited by 8,599 · see citing works
The Path Forward for Biofuels and Biomaterials
Ragauskas, A. J., Williams, C. K., Davison, B. H., Britovsek, G., Cairney, J., Eckert, C. A., Frederick, W. J., Hallett, J. P., Leak, D. J., Liotta, C. L., et al. (2006) · Science · doi:10.1126/science.1114736 · Cited by 5,741 · see citing works
Self-citationSolvent-Free Organic Synthesis
Tanaka, K., & Toda, F. (2000) · Chemical Reviews · doi:10.1021/cr940089p · Cited by 2,104 · see citing works
Weissermel, K., & Arpe, H. (1997) · Wiley eBooks · doi:10.1002/9783527616688 · Cited by 1,877 · see citing works
Cammarata, L., Kazarian, S. G., Salter, P. A., & Welton, T. (2001) · Physical Chemistry Chemical Physics · doi:10.1039/b106900d · Cited by 1,441 · see citing works
Self-citationDissolution of cellulose with ionic liquids and its application: a mini-review
Zhu, S., Wu, Y., Chen, Q., Yu, Z., Wang, C., Jin, S., Ding, Y., & Wu, G. (2006) · Green Chemistry · doi:10.1039/b601395c · Cited by 1,260 · see citing works
Novel Brønsted Acidic Ionic Liquids and Their Use as Dual Solvent−Catalysts
Cole, A. C., Jensen, J. L., Ntai, I., Tran, K. L. T., Weaver, K. J., Forbes, D. C., & Davis, J. H. (2002) · Journal of the American Chemical Society · doi:10.1021/ja026290w · Cited by 1,198 · see citing works
Solvent–solute interactions in ionic liquids
Crowhurst, L., Mawdsley, P. R., Perez‐Arlandis, J. M., Salter, P. A., & Welton, T. (2003) · Physical Chemistry Chemical Physics · doi:10.1039/b303095d · Cited by 776 · see citing works
Self-citationPerspective on Solvent Use in the Pharmaceutical Industry
Constable, D. J. C., Jimenez-Gonzalez, C., & Henderson, R. K. (2007) · Organic Process Research & Development · doi:10.1021/op060170h · Cited by 744 · see citing works
A guidebook to mechanism in organic chemistry
Sykes, P. J. (1962) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 672 · see citing works
Applications of Ionic Liquids in Carbohydrate Chemistry: A Window of Opportunities
Seoud, O. A. E., Koschella, A., Fidale, L. C., Dorn, S., & Heinze, T. J. (2007) · Biomacromolecules · doi:10.1021/bm070062i · Cited by 668 · see citing works
Synthesis of functionalized biodegradable polyesters
Williams, C. K. (2007) · Chemical Society Reviews · doi:10.1039/b614342n · Cited by 454 · see citing works
Self-citationAlternative Solvents: Shades of Green
Clark, J. H., & Tavener, S. J. (2006) · Organic Process Research & Development · doi:10.1021/op060160g · Cited by 406 · see citing works
Room-temperature ionic liquids that dissolve carbohydrates in high concentrations
Liu, Q., Janssen, M. H. A., van Rantwijk, F., & Sheldon, R. A. (2004) · Green Chemistry · doi:10.1039/b412848f · Cited by 371 · see citing works
Ionic Liquids: The Neglected Issues
Scammells, P. J., Scott, J. L., & Singer, R. D. (2005) · Australian Journal of Chemistry · doi:10.1071/ch04272 · Cited by 278 · see citing works
Crowhurst, L., Falcone, R. D., Lancaster, N. L., Llopis‐Mestre, V., & Welton, T. (2006) · The Journal of Organic Chemistry · doi:10.1021/jo0615302 · Cited by 164 · see citing works
Self-citationForbes, D. C. (2004) · Journal of Molecular Catalysis A Chemical · doi:10.1016/j.molcata.2003.09.035 · Cited by 147 · see citing works
Abraham, M. H., & Acree, W. E. (2006) · Green Chemistry · doi:10.1039/b606279b · Cited by 141 · see citing works
Funatomi, T., Wakasugi, K., Misaki, T., & Tanabe, Y. (2006) · Green Chemistry · doi:10.1039/b609181b · Cited by 118 · see citing works
Enzymatic polyester synthesis in ionic liquids
Marcilla, R., de Geus, M., Mecerreyes, D., Duxbury, C. J., Koning, C. E., & Heise, A. (2006) · European Polymer Journal · doi:10.1016/j.eurpolymj.2005.12.021 · Cited by 98 · see citing works
Lee, S. H., Dang, D. T., Ha, S. H., Chang, W., & Koo, Y. (2007) · Biotechnology and Bioengineering · doi:10.1002/bit.21534 · Cited by 98 · see citing works
Ganeshpure, P. A., George, G., & Das, J. (2007) · Journal of Molecular Catalysis A Chemical · doi:10.1016/j.molcata.2007.06.025 · Cited by 70 · see citing works
The relationship between solvent polarity and molar volume in room-temperature ionic liquids
Kobrak, M. N. (2007) · Green Chemistry · doi:10.1039/b711991g · Cited by 68 · see citing works
A green approach for the synthesis of long chain aliphatic acid esters at room temperature
Li, X., & Eli, W. (2007) · Journal of Molecular Catalysis A Chemical · doi:10.1016/j.molcata.2007.08.032 · Cited by 66 · see citing works
Nucleophilic Reactions at Cationic Centers in Ionic Liquids and Molecular Solvents
Ranieri, G. A., Hallett, J. P., & Welton, T. (2007) · Industrial & Engineering Chemistry Research · doi:10.1021/ie070632v · Cited by 66 · see citing works
Self-citationSakakura, A., Nakagawa, S., & Ishihara, K. (2005) · Tetrahedron · doi:10.1016/j.tet.2005.09.059 · Cited by 49 · see citing works
Proton speciation in ambient-temperature chloroaluminate ionic liquids
Trulove, P. C., & Osteryoung, R. A. (1992) · Inorganic Chemistry · doi:10.1021/ic00045a023 · Cited by 43 · see citing works
Meter, D. S. V., Sun, Y., Parker, K. M., & Stalcup, A. M. (2007) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-007-1739-4 · Cited by 36 · see citing works
Jiang, T., Chang, Y., Zhao, G., Han, B., & Yang, G. (2004) · Synthetic Communications · doi:10.1081/scc-120027257 · Cited by 27 · see citing works
Campbell, J. L. E., & Johnson, K. E. (1994) · Journal of The Electrochemical Society · doi:10.1149/1.2054822 · Cited by 12 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Room-Temperature Ionic Liquids: Solvents for Synthesis and Catalysis. 2
Hallett, J. P., & Welton, T. (2011) · Chemical Reviews · doi:10.1021/cr1003248 · Cited by 12,581 · see citing works
Self-citationIonic liquids and catalysis: Recent progress from knowledge to applications
Olivier‐Bourbigou, H., Magna, L., & Morvan, D. L. (2009) · Applied Catalysis A General · doi:10.1016/j.apcata.2009.10.008 · Cited by 1,639 · see citing works
Deconstruction of lignocellulosic biomass with ionic liquids
Brandt, A., Gräsvik, J., Hallett, J. P., & Welton, T. (2013) · Green Chemistry · doi:10.1039/c2gc36364j · Cited by 1,557 · see citing works
Self-citationUnderstanding the polarity of ionic liquids
Rani, M. A. A., Brant, A., Crowhurst, L., Dolan, A., Lui, M. Y.-Y., Hassan, N. H., Hallett, J. P., Hunt, P. A., Niedermeyer, H., Perez‐Arlandis, J. M., et al. (2011) · Physical Chemistry Chemical Physics · doi:10.1039/c1cp21262a · Cited by 524 · see citing works
Self-citationThe effect of the ionic liquid anion in the pretreatment of pine wood chips
Brandt, A., Hallett, J. P., Leak, D. J., Murphy, R. J., & Welton, T. (2010) · Green Chemistry · doi:10.1039/b918787a · Cited by 333 · see citing works
Self-citationExtended scale for the hydrogen-bond basicity of ionic liquids
Cláudio, A. F. M., Swift, L., Hallett, J. P., Welton, T., Coutinho, J. A. P., & Freire, M. G. (2014) · Physical Chemistry Chemical Physics · doi:10.1039/c3cp55285c · Cited by 248 · see citing works
Self-citationTriblock copolymers from lactide and telechelic poly(cyclohexene carbonate)
Kember, M. R., Copley, J., Buchard, A., & Williams, C. K. (2012) · Polymer Chemistry · doi:10.1039/c2py00543c · Cited by 123 · see citing works
Self-citationUpdate 1 of: Ionic Liquids in Heterocyclic Synthesis
Martins, M. A. P., Frizzo, C. P., Tier, A. Z., Moreira, D. N., Zanatta, N., & Bonacorso, H. G. (2014) · Chemical Reviews · doi:10.1021/cr500106x · Cited by 113 · see citing works
Structural features of ionic liquids: consequences for material preparation and organic reactivity
Weber, C. C., Masters, A. F., & Maschmeyer, T. (2013) · Green Chemistry · doi:10.1039/c3gc41313f · Cited by 101 · see citing works
Clark, J. H., MacQuarrie, D. J., & Sherwood, J. R. (2011) · Green Chemistry · doi:10.1039/c1gc16299c · Cited by 96 · see citing works
Ionic liquids: Solvation ability and polarity
Chiappe, C., Malvaldi, M., & Pomelli, C. S. (2009) · Pure and Applied Chemistry · doi:10.1351/pac-con-08-09-08 · Cited by 86 · see citing works
Strategies for the Separation of the Furanic Compounds HMF, DFF, FFCA, and FDCA from Ionic Liquids
Ghatta, A. A., Wilton‐Ely, J. D. E. T., & Hallett, J. P. (2019) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.9b03613 · Cited by 83 · see citing works
Self-citationMechanisms of Degradation of Paraoxon in Different Ionic Liquids
Pávez, P., Millán, D., Morales, J. I., Castro, E. A., Claudio López, A., & Santos, J. G. (2013) · The Journal of Organic Chemistry · doi:10.1021/jo401351v · Cited by 80 · see citing works
Clark, J. H., MacQuarrie, D. J., & Sherwood, J. R. (2013) · Chemistry - A European Journal · doi:10.1002/chem.201204396 · Cited by 75 · see citing works
Tao, Y., Dong, R., Pavlidis, Ι. V., Chen, B., & Tan, T. (2015) · Green Chemistry · doi:10.1039/c5gc02557e · Cited by 73 · see citing works
Intramolecular Diels−Alder Reaction in Ionic Liquids: Effect of Ion-Specific Solvent Friction
Tiwari, S. S., Khupse, N. D., & Kumar, A. (2008) · The Journal of Organic Chemistry · doi:10.1021/jo801802q · Cited by 70 · see citing works
Palgunadi, J., Hong, S. Y., Lee, J. K., Lee, H., Lee, S. D., Cheong, M., & Kim, H. S. (2011) · The Journal of Physical Chemistry B · doi:10.1021/jp108351f · Cited by 68 · see citing works
Naert, P., Rabaey, K., & Stevens, C. V. (2018) · Green Chemistry · doi:10.1039/c8gc01869c · Cited by 58 · see citing works
Cellante, L., Costa, R., Monaco, I., Cenacchi, G., & Locatelli, E. (2018) · New Journal of Chemistry · doi:10.1039/c7nj04633b · Cited by 47 · see citing works
Ionic Liquid Structure-Induced Effects on Organic Reactions
Stark, A. (2008) · Topics in current chemistry · doi:10.1007/128_2008_43 · Cited by 46 · see citing works
D’Anna, F., Marullo, S., Vitale, P., & Noto, R. (2011) · European Journal of Organic Chemistry · doi:10.1002/ejoc.201100763 · Cited by 43 · see citing works
Cao, Y., Chen, Y., Wang, X., & Mu, T. (2013) · RSC Advances · doi:10.1039/c3ra44464c · Cited by 41 · see citing works
Ghatta, A. A., Wilton‐Ely, J. D. E. T., & Hallett, J. P. (2019) · ChemSusChem · doi:10.1002/cssc.201901529 · Cited by 41 · see citing works
Self-citationSakakura, A., Koshikari, Y., Akakura, M., & Ishihara, K. (2011) · Organic Letters · doi:10.1021/ol2027366 · Cited by 40 · see citing works
Tankov, I., & Yankova, R. (2018) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2018.12.087 · Cited by 39 · see citing works
Chighine, A., Crosignani, S., Arnal, M., Bradley, M., & Linclau, B. (2009) · The Journal of Organic Chemistry · doi:10.1021/jo900476y · Cited by 36 · see citing works
A Study of the Influence of Ionic Liquids Properties on the Kemp Elimination Reaction
D’Anna, F., Marca, S., Meo, P. L., & Noto, R. (2009) · Chemistry - A European Journal · doi:10.1002/chem.200900148 · Cited by 36 · see citing works
Wei, H., Li, J., Yu, J., Zheng, J., Su, H., & Wang, X. (2014) · Inorganica Chimica Acta · doi:10.1016/j.ica.2014.11.024 · Cited by 35 · see citing works
Goswami, S. R., Wang, S., Gnanasekar, P., Chauhan, P., & Yan, N. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.115892 · Cited by 35 · see citing works
Priede, E., Briča, S., Baķis, E., Udris, N., & Zicmanis, A. (2015) · New Journal of Chemistry · doi:10.1039/c5nj01906k · Cited by 34 · see citing works
A Method of Calculating the Kamlet–Abboud–Taft Solvatochromic Parameters Using COSMO-RS
Sherwood, J. R., Granelli, J., McElroy, C. R., & Clark, J. H. (2019) · Molecules · doi:10.3390/molecules24122209 · Cited by 33 · see citing works
Pávez, P., Millán, D., Cocq, C., Santos, J. G., & Nome, F. (2014) · New Journal of Chemistry · doi:10.1039/c4nj02121e · Cited by 28 · see citing works
Ionic liquids as media for biomass processing: opportunities and restrictions
Schrems, M., Brandt‐Talbot, A., Welton, T., Liebner, F. W., Rosenau, T., & Potthast, A. (2011) · Holzforschung · doi:10.1515/hf.2011.099 · Cited by 28 · see citing works
Self-citationp-Cymenesulphonic acid: An organic acid synthesised from citrus waste
Clark, J. H., Fitzpatrick, E. M., MacQuarrie, D. J., Pfaltzgraff, L. A., & Sherwood, J. R. (2012) · Catalysis Today · doi:10.1016/j.cattod.2011.12.007 · Cited by 28 · see citing works
Phosphoric-based ionic liquids as solvents to separate the azeotropic mixture of ethanol and hexane
Cai, F., Zhao, M., Wang, Y., Wang, F., & Xiao, G. (2014) · The Journal of Chemical Thermodynamics · doi:10.1016/j.jct.2014.09.019 · Cited by 27 · see citing works
Przypis, M., Matuszek, K., Chrobok, A., Swadźba‐Kwaśny, M., & Gillner, D. (2020) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2020.113166 · Cited by 26 · see citing works
Solvent effects of ionic liquids: investigation of ferrocenes as electrochemical probes
Bizzarri, C., Conte, V., Floris, B., & Galloni, P. (2010) · Journal of Physical Organic Chemistry · doi:10.1002/poc.1759 · Cited by 25 · see citing works
Passos, H., Dinis, T. B. V., Cláudio, A. F. M., Freire, M. G., & Coutinho, J. A. P. (2018) · Physical Chemistry Chemical Physics · doi:10.1039/c8cp01401a · Cited by 25 · see citing works
Recent Progress on Starch Maleate/Polylactic Acid Blends for Compostable Food Packaging Applications
Goswami, S. R., Nair, S. S., Sen, W., & Yan, N. (2021) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.1c04940 · Cited by 24 · see citing works
Green Solvents as a Promising Approach to Degradation of Organophosphorate Pesticides
Pávez, P., Oliva, G., & Millán, D. (2016) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.6b01923 · Cited by 24 · see citing works
New approach to hydrosilylation reaction in ionic liquids as solvent in microreactor system
Kukawka, R., Pawlowska-Zygarowicz, A., Dutkiewicz, M., Maciejewski, H., & Śmiglak, M. (2016) · RSC Advances · doi:10.1039/c6ra08278e · Cited by 23 · see citing works
Prado, R., & Weber, C. C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-444-63713-0.00001-8 · Cited by 23 · see citing works
The Base-Catalyzed Keto−Enol Interconversion of 2-Nitrocyclohexanone in Ionic Liquids
Angelini, G., Maria, P. D., Chiappe, C., Fontana, A., Gasbarri, C., & Siani, G. (2009) · The Journal of Organic Chemistry · doi:10.1021/jo901029c · Cited by 20 · see citing works
Lanctôt, A. G., Attard, T. M., Sherwood, J. R., McElroy, C. R., & Hunt, A. J. (2016) · RSC Advances · doi:10.1039/c6ra10275a · Cited by 20 · see citing works
Theoretical study on the interactions between methanol and imidazolium-based ionic liquids
Zhu, X., Sun, H., Zhang, D., & Liu, C. (2010) · Journal of Molecular Modeling · doi:10.1007/s00894-010-0879-1 · Cited by 18 · see citing works
D’Anna, F., Marullo, S., Vitale, P., & Noto, R. (2010) · The Journal of Organic Chemistry · doi:10.1021/jo100914p · Cited by 17 · see citing works
Wei, X., Zhang, X., Jiang, Y., Liao, H., Lai, W., Dai, S., An, P., Wang, Z.-Q., & Hou, Z. (2024) · Journal of Catalysis · doi:10.1016/j.jcat.2024.115493 · Cited by 15 · see citing works
Clark, J. H., Farmer, T. J., MacQuarrie, D. J., & Sherwood, J. R. (2013) · Sustainable Chemical Processes · doi:10.1186/2043-7129-1-23 · Cited by 15 · see citing works
Cai, F., Ibrahim, J. J., Lei, N., Xu, W., & Xiao, G. (2014) · Journal of Chemical & Engineering Data · doi:10.1021/je500672d · Cited by 15 · see citing works
Kukawka, R., Januszewski, R., Kownacki, I., Śmiglak, M., & Maciejewski, H. (2018) · Catalysis Communications · doi:10.1016/j.catcom.2018.01.021 · Cited by 15 · see citing works
Park, T.-J., Kim, Y. S., Kan, E., & Lee, S. H. (2015) · RSC Advances · doi:10.1039/c5ra01003a · Cited by 10 · see citing works
The acetate anion promotes hydrolysis of poly(ethylene terephthalate) in ionic liquid–water mixtures
Suleman, M. Y., Judah, H. L., Bexis, P., Fennell, P. S., Hallett, J. P., & Brandt‐Talbot, A. (2025) · Green Chemistry · doi:10.1039/d5gc02409a · Cited by 9 · see citing works
Self-citationNaydenov, D., Hasse, H., Maurer, G., & Bart, H. (2009) · The Open Chemical Engineering Journal · doi:10.2174/1874123100903010017 · Cited by 9 · see citing works
Green Organic Synthesis in Ionic Liquids
Wasserscheid, P., & Joni, J. (2010) · Wiley eBooks · doi:10.1002/9783527628698.hgc061 · Cited by 8 · see citing works
Ehman, N. V., Rodríguez‐Fabià, S., Zehner, J., & Chinga‐Carrasco, G. (2024) · Composites Part A Applied Science and Manufacturing · doi:10.1016/j.compositesa.2024.108247 · Cited by 7 · see citing works
Xu, X., Azuma, A., Taniguchi, M., Tokunaga, E., & Shibata, N. (2013) · RSC Advances · doi:10.1039/c3ra00132f · Cited by 7 · see citing works
Catalytic Reaction in Ionic Liquids
Ozokwelu, D. E., Zhang, S., Okafor, O. C., Cheng, W., & Litombe, N. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-802027-2.00004-2 · Cited by 6 · see citing works
Gi̇ray, E. S., Chiappe, C., Tunalı, Z., & Rajamani, S. (2011) · RSC Advances · doi:10.1039/c1ra00031d · Cited by 6 · see citing works
Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives
Bedford, C. T. (2011) · Organic Reaction Mechanisms/Organic reaction mechanisms · doi:10.1002/9780470979525.ch2 · Cited by 6 · see citing works
Room-Temperature Ionic Liquids and Eutectic Mixtures
(2013) · Royal Society of Chemistry eBooks · doi:10.1039/9781849736824-00175 · Cited by 5 · see citing works
Goswami, S. R., Wang, S., & Yan, N. (2023) · ACS Applied Polymer Materials · doi:10.1021/acsapm.2c01917 · Cited by 2 · see citing works
Wang, Y., Ding, Q., Liu, S., Li, H., & Gao, X. (2026) · Journal of Chemical & Engineering Data · doi:10.1021/acs.jced.5c00726 · Cited by 1 · see citing works
dos Santos, J. R. N., Ramos, L. M., de Morais, J. G., Passos, S. T. A., de Oliveira, A. L., Machado, F., & Neto, B. A. D. (2026) · ACS Organic & Inorganic Au · doi:10.1021/acsorginorgau.6c00059 · Cited by 1 · see citing works
(2009) · Royal Society of Chemistry eBooks · doi:10.1039/bk9781847551610-00146
- Authors
- Wells, T. P., Hallett, J. P., Williams, C. K., & Welton, T.
- Affiliations
- Imperial College London (GB)
- Venue
- The Journal of Organic Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-06-17
- Volume
- 73
- Issue
- 14
- Pages
- 5585-5588
- ISSN
- 0022-3263 (ISSN-L)
- 1520-6904
- OpenAlex
- W2072442685
- Cited by
- 65
- References
- 32
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 2 · 2023: 1 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 5 · 2017: 1 · 2016: 4 · 2015: 3 · 2014: 6 · 2013: 7 · 2012: 4
- FWCI
- 3.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Organic Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemical Engineering › Catalysis › Ionic liquids properties and applications
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Synthesis and Reactions
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Reaction Mechanisms
- Keywords
- esterification, ionic liquids, solvent basicity, methoxyacetic acid, benzyl alcohol, second-order rate constants, linear solvation energy relationships, hydrogen-bond basicity, solvent effects on reaction rates
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
