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Cited by 258

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Fluorescence Resonance Energy Transfer in CdSe/ZnS−DNA Conjugates: Probing Hybridization and DNA Cleavage

Gill, Ron, Willner, Itamar, Shweky, Itzhak, Banin, Uri·2005·The Journal of Physical Chemistry B

Abstract

Nucleic-acid-functionalized CdSe/ZnS quantum dots (QDs) were hybridized with the complementary Texas-Red-functionalized nucleic acid. The hybridization was monitored by following the fluorescence resonance energy transfer from the QDs to the dye units. Treatment of the QD/dye DNA duplex structure with DNase I resulted in the cleavage of the DNA and the recovery of the fluorescence properties of the CdSe/ZnS QDs. The luminescence properties of the QDs were, however, only partially recovered due to the nonspecific adsorption of the dye onto the QDs. Similarly, nucleic-acid-functionalized Au nanoparticles (Au NPs) were hybridized with the complementary Texas-Red-labeled nucleic acid. The hybridization was followed by the fluorescence quenching of the dye by the Au NPs. Treatment of the Au NP/dye DNA duplex with DNase I resulted in the cleavage of the DNA and the partial recovery of the dye fluorescence. The incomplete recovery of the dye fluorescence originated from the nonspecific binding of the dye units to the Au NPs. The nonspecific binding of the dye to the CdSe/ZnS QDs and the Au NPs is attributed to nonprotected surface vacancies in the two systems.

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Crossref · 10.1021/jp054874p

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Metadata

Authors
Gill, R., Willner, I., Shweky, I., & Banin, U.
Venue
The Journal of Physical Chemistry B
Published
2005-11-19
Volume
109
Issue
49
Pages
23715-23719
ISSN
  • 1520-5207 (ISSN-L)
  • 1520-6106
OpenAlex
W1983972900
Cited by
258
References
8
FWCI
6.22
Type
journal article
Language
en
Open access
closed

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