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Biodistribution of Pristine Single-Walled Carbon Nanotubes In Vivo
Abstract
The biodistribution of pristine single-walled carbon nanotubes (SWNTs) in mice was determined by using the skeleton 13 C-enriched SWNTs and isotope ratio mass spectroscopy. The results suggested that the SWNTs were distributed in the entire body, with major accumulations in the liver, lungs, and spleen over an extended period of time. The specimen from the effected organ tissues were examined by using transmission electron microscopy, aimed toward an understanding of the possible uptake mechanism. The biological consequence of pristine SWNTs is obviously very different from that of their chemically modified or functionalized counterparts. The implication of such a fact is discussed.
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Citations
Cited by
Sharifi, S., Behzadi, S., Laurent, S., Laird Forrest, M., Stroeve, P., & Mahmoudi, M. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15188f · Cited by 1,460
Liu, Z., Davis, C., Cai, W., He, L., Chen, X., & Dai, H. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707654105 · Cited by 1,116
Promises, facts and challenges for carbon nanotubes in imaging and therapeutics
Kostarelos, K., Bianco, A., & Prato, M. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.241 · Cited by 787
Ren, J., Shen, S., Wang, D., Xi, Z., Guo, L., Pang, Z., Qian, Y., Sun, X., & Jiang, X. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.01.025 · Cited by 408
Biological interactions of carbon-based nanomaterials: From coronation to degradation
Bhattacharya, K., Mukherjee, S. P., Gallud, A., Burkert, S. C., Bistarelli, S., Bellucci, S., Bottini, M., Star, A., & Fadeel, B. (2016) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2015.11.011 · Cited by 402
Metadata
- Authors
- Yang, S.-T., Guo, W., Lin, Y., Deng, X.-Y., Wang, H.-F., Sun, H.-F., Liu, Y.-F., Wang, X., Wang, W., Chen, M., Huang, Y.-P., & Sun, Y.-P.
- Venue
- The Journal of Physical Chemistry C
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-06-19
- Volume
- 111
- Issue
- 48
- Pages
- 17761-17764
- ISSN
- 1932-7447 (ISSN-L)
- 1932-7455
- OpenAlex
- W2046326845
- Cited by
- 259
- References
- 0
- FWCI
- 9.60
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yang, S.-T., Guo, W., Lin, Y., Deng, X.-Y., Wang, H.-F., Sun, H.-F., Liu, Y.-F., Wang, X., Wang, W., Chen, M., Huang, Y.-P., & Sun, Y.-P. (2007). Biodistribution of Pristine Single-Walled Carbon Nanotubes In Vivo. The Journal of Physical Chemistry C. https://doi.org/10.1021/jp070712c
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