The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Photothermal Efficiencies of Nanoshells and Nanorods for Clinical Therapeutic Applications
Abstract
With clinical trials for photothermal tumor ablation using laser-excited tunable plasmonic nanoparticles already underway, increasing understanding of the efficacy of plasmonic nanoparticle-based photothermal heating takes on increased urgency. Here we report a comparative study of the photothermal transduction efficiency of SiO 2 /Au nanoshells, Au 2 S/Au nanoshells, and Au nanorods, directly relevant to applications that rely on the photothermal response of plasmonic nanoparticles. We compare the experimental photothermal transduction efficiencies with the theoretical absorption efficiencies for each nanoparticle type. Our analysis assumes a distribution of randomly oriented nanorods, as would occur naturally in the tumor vasculature. In our study, photothermal transduction efficiencies differed by a factor of 3 or less between the different types of nanoparticle studied. Both experiment and theory show that particle size plays a dominant role in determining transduction efficiency, with larger particles more efficient for both absorption and scattering, enabling simultaneous photothermal heating and bioimaging contrast enhancement.
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Cites
Optical Constants of the Noble Metals
Johnson, P. B., & Christy, R. W. (1972) · Physical Review B · doi:10.1103/physrevb.6.4370 · Cited by 20,094
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A Plasmonic Gold Nanostar Theranostic Probe for In Vivo Tumor Imaging and Photothermal Therapy
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Strategies to Improve Cancer Photothermal Therapy Mediated by Nanomaterials
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Metadata
- Authors
- Cole, J. R., Mirin, N. A., Knight, M. W., Goodrich, G. P., & Halas, N. J.
- Venue
- The Journal of Physical Chemistry C
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-06-11
- Volume
- 113
- Issue
- 28
- Pages
- 12090-12094
- ISSN
- 1932-7447 (ISSN-L)
- 1932-7455
- OpenAlex
- W1980257336
- Cited by
- 378
- References
- 1
- FWCI
- 10.87
- Type
- journal article
- Language
- en
- Open access
- closed
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