The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Oxidation-Sensitive Polymeric Nanoparticles
Abstract
We have recently demonstrated the possible use of organic polysulfides for the design of oxidation-sensitive colloidal carriers in the form of polymeric vesicles, which are particularly suitable for the encapsulation of hydrosoluble drugs. In the present research we extend our efforts to carriers specifically suitable for hydrophobic molecules. Exploiting the living emulsion polymerization of episulfides, we have produced new cross-linked polysulfide nanoparticles. Here we demonstrate how this process allows the production of stable nanoparticles with a good control over their size and functionality. The nanoparticles showed negligible cytotoxicity on a fibroblast model; furthermore, they exhibited sensitivity to oxidative conditions, which first produce swelling and then solubilize the material.
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Cites
Polymeric systems for controlled drug release
Uhrich, K. E., Cannizzaro, S. M., Langer, R. S., & Shakesheff, K. M. (1999) · Chemical Reviews · doi:10.1021/cr940351u · Cited by 2,633
Bingle, L., Brown, N. J., & Lewis, C. E. (2002) · The Journal of Pathology · doi:10.1002/path.1027 · Cited by 2,022
Cited by
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Reddy, S. T., Swartz, M. A., & Hubbell, J. A. (2006) · Trends in Immunology · doi:10.1016/j.it.2006.10.005 · Cited by 406
Self-citationOn the biodegradability of polyethylene glycol, polypeptoids and poly(2-oxazoline)s
Ulbricht, J., Jordan, R., & Luxenhofer, R. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.02.029 · Cited by 348
Thomas, S. N., Vokali, E., Lund, A. W., Hubbell, J. A., & Swartz, M. A. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2013.10.003 · Cited by 310
Self-citationStimuli-Responsive Nanomaterials for Application in Antitumor Therapy and Drug Delivery
Pham, S. H., Choi, Y., & Choi, J. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12070630 · Cited by 248
Velluto, D., Demurtas, D., & Hubbell, J. A. (2008) · Molecular Pharmaceutics · doi:10.1021/mp7001297 · Cited by 110
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Metadata
- Authors
- Rehor, A., Hubbell, J. A., & Tirelli, N.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-12-02
- Volume
- 21
- Issue
- 1
- Pages
- 411-417
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2059486762
- Cited by
- 161
- References
- 2
- FWCI
- 2.71
- Type
- journal article
- Language
- en
- Open access
- closed
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
