The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Controlled Production of Monodisperse Double Emulsions by Two-Step Droplet Breakup in Microfluidic Devices
Abstract
A microfluidic device having both hydrophobic and hydrophilic components is exploited for production of multiple-phase emulsions. For producing water-in-oil-in-water (W/O/W) dispersions, aqueous droplets ruptured at the upstream hydrophobic junction are enclosed within organic droplets formed at the downstream hydrophilic junction. Droplets produced at each junction could have narrow size distributions with coefficients of variation in diameter of less than 3%. Control of the flow conditions produces variations in internal/external droplet sizes and in the internal droplet number. Both W/O/W emulsions (with two types of internal droplets) and oil-in-water-in-oil emulsions were prepared by varying geometry and wettability in microchannels.
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Citations
Cites
Formation of dispersions using “flow focusing” in microchannels
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Dynamic Pattern Formation in a Vesicle-Generating Microfluidic Device
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Monodisperse Emulsion Generation via Drop Break Off in a Coflowing Stream
Umbanhowar, P. B., Prasad, V., & Weitz, D. A. (2000) · Langmuir · doi:10.1021/la990101e · Cited by 693
Droplet formation in a microchannel network
Nisisako, T., Torii, T., & Higuchi, T. (2002) · Lab Chip · doi:10.1039/b108740c · Cited by 607
Self-citationOGAWA, Y., YAMAMOTO, M., OKADA, H., YASHIKI, T., & SHIMAMOTO, T. (1988) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.36.1095 · Cited by 505
The intensification of rapid reactions in multiphase systems using slug flow in capillaries
Burns, J. R., & Ramshaw, C. (2001) · Lab on a Chip · doi:10.1039/b102818a · Cited by 503
Particle control of emulsion by membrane emulsification and its applications
Nakashima, T., Shimizu, M., & Kukizaki, M. (2000) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00099-5 · Cited by 406
Ordered and Disordered Patterns in Two-Phase Flows in Microchannels
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Cited by
Formation of droplets and bubbles in a microfluidic T-junction—scaling and mechanism of break-up
Garstecki, P., Fuerstman, M. J., Stone, H. A., & Whitesides, G. M. (2006) · Lab on a Chip · doi:10.1039/b510841a · Cited by 2,339
Surfactants in droplet-based microfluidics
Baret, J.-C. (2012) · Lab Chip · doi:10.1039/c1lc20582j · Cited by 649
Microfluidic Devices for Bioapplications
Yeo, L. Y., Chang, H., Chan, P. P. Y., & Friend, J. R. (2011) · Small · doi:10.1002/smll.201000946 · Cited by 622
Monodisperse Alginate Hydrogel Microbeads for Cell Encapsulation
Tan, W. ‐., & Takeuchi, S. (2007) · Advanced Materials · doi:10.1002/adma.200700433 · Cited by 599
Polymer Particles with Various Shapes and Morphologies Produced in Continuous Microfluidic Reactors
Nie, Z., Xu, S., Seo, M., Lewis, P. C., & Kumacheva, E. (2005) · Journal of the American Chemical Society · doi:10.1021/ja042494w · Cited by 531
Metadata
- Authors
- Okushima, S., Nisisako, T., Torii, T., & Higuchi, T.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-10-08
- Volume
- 20
- Issue
- 23
- Pages
- 9905-9908
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W1995979590
- Cited by
- 656
- References
- 15
- FWCI
- 19.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- Okushima, S., Nisisako, T., Torii, T., & Higuchi, T. (2004). Controlled Production of Monodisperse Double Emulsions by Two-Step Droplet Breakup in Microfluidic Devices. Langmuir. https://doi.org/10.1021/la0480336
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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