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Formation of droplets and bubbles in a microfluidic T-junction—scaling and mechanism of break-up
Abstract
This article describes the process of formation of droplets and bubbles in microfluidic T-junction geometries. At low capillary numbers break-up is not dominated by shear stresses: experimental results support the assertion that the dominant contribution to the dynamics of break-up arises from the pressure drop across the emerging droplet or bubble. This pressure drop results from the high resistance to flow of the continuous (carrier) fluid in the thin films that separate the droplet from the walls of the microchannel when the droplet fills almost the entire cross-section of the channel. A simple scaling relation, based on this assertion, predicts the size of droplets and bubbles produced in the T-junctions over a range of rates of flow of the two immiscible phases, the viscosity of the continuous phase, the interfacial tension, and the geometrical dimensions of the device.
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Citations
Cites
Millisecond Kinetics on a Microfluidic Chip Using Nanoliters of Reagents
Song, H., & Ismagilov, R. F. (2003) · Journal of the American Chemical Society · doi:10.1021/ja0354566 · Cited by 693
Cited by
Seemann, R., Brinkmann, M., Pfohl, T., & Herminghaus, S. (2012) · Reports on Progress in Physics · doi:10.1088/0034-4885/75/1/016601 · Cited by 1,049
Dripping and jetting in microfluidic multiphase flows applied to particle and fibre synthesis
Nunes, J. K., Tsai, S. S. H., Wan, J., & Stone, H. A. (2013) · Journal of Physics D: Applied Physics · doi:10.1088/0022-3727/46/11/114002 · Cited by 406
Self-citationIndustrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery
Vladisavljević, G. T., Khalid, N., Neves, M. A., Kuroiwa, T., Nakajima, M., Uemura, K., Ichikawa, S., & Kobayashi, I. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.07.017 · Cited by 313
Grenoble, Z., & Trabelsi, S. (2018) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2018.08.003 · Cited by 120
Guanxing, Z., Liu, Z., Deng, W., & Zhu, W. (2021) · Journal of Optics · doi:10.1088/2040-8986/abcc52 · Cited by 34
Metadata
- Authors
- Garstecki, P., Fuerstman, M. J., Stone, H. A., & Whitesides, G. M.
- Venue
- Lab on a Chip
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2006
- Volume
- 6
- Issue
- 3
- Pages
- 437
- ISSN
- 1473-0189 (ISSN-L)
- 1473-0197
- OpenAlex
- W2142423992
- Cited by
- 2,339
- References
- 1
- FWCI
- 50.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- Garstecki, P., Fuerstman, M. J., Stone, H. A., & Whitesides, G. M. (2006). Formation of droplets and bubbles in a microfluidic T-junction—scaling and mechanism of break-up. Lab on a Chip. https://doi.org/10.1039/b510841a
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.