The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Silica-Coated Gold Nanostars for Combined Surface-Enhanced Raman Scattering (SERS) Detection and Singlet-Oxygen Generation: A Potential Nanoplatform for Theranostics
Open accessAbstract
This paper reports the synthesis and characterization of surface-enhanced Raman scattering (SERS) label-tagged gold nanostars, coated with a silica shell containing methylene blue photosensitizing drug for singlet-oxygen generation. To our knowledge, this is the first report of nanocomposites possessing a combined capability for SERS detection and singlet-oxygen generation for photodynamic therapy. The gold nanostars were tuned for maximal absorption in the near-infrared (NIR) spectral region and tagged with a NIR dye for surface-enhanced resonance Raman scattering (SERRS). Silica coating was used to encapsulate the photosensitizer methylene blue in a shell around the nanoparticles. Upon 785 nm excitation, SERS from the Raman dye is observed, while excitation at 633 nm shows fluorescence from methylene blue. Methylene-blue-encapsulated nanoparticles show a significant increase in singlet-oxygen generation as compared to nanoparticles synthesized without methylene blue. This increased singlet-oxygen generation shows a cytotoxic effect on BT549 breast cancer cells upon laser irradiation. The combination of SERS detection (diagnostic) and singlet-oxygen generation (therapeutic) into a single platform provides a potential theranostic agent.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Vo-Dinh, T. (1998) · TrAC Trends in Analytical Chemistry · doi:10.1016/s0165-9936(98)00069-7 · Cited by 498
Self-citation
Cited by
Jokerst, J. V., Cole, A. J., Van de Sompel, D., & Gambhir, S. S. (2012) · ACS Nano · doi:10.1021/nn304347g · Cited by 397
Surface-enhanced Raman scattering in cancer detection and imaging
Vendrell, M., Maiti, K. K., Dhaliwal, K., & Chang, Y.-T. (2013) · Trends in Biotechnology · doi:10.1016/j.tibtech.2013.01.013 · Cited by 375
Emerging advances in nanomedicine with engineered gold nanostructures
Webb, J. A., & Bardhan, R. (2014) · Nanoscale · doi:10.1039/c3nr05112a · Cited by 324
Single Cell Optical Imaging and Spectroscopy
Stender, A. S., Marchuk, K., Liu, C., Sander, S., Meyer, M. W., Smith, E. A., Neupane, B., Wang, G., Li, J., Cheng, J.-X., et al. (2013) · Chemical Reviews · doi:10.1021/cr300336e · Cited by 292
Plasmonics-based SERS nanobiosensor for homogeneous nucleic acid detection
Wang, H.-N., Fales, A. M., & Vo-Dinh, T. (2015) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2014.12.012 · Cited by 71
Self-citation
Metadata
- Authors
- Fales, A. M., Yuan, H., & Vo-Dinh, T.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-09-02
- Volume
- 27
- Issue
- 19
- Pages
- 12186-12190
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2038750423
- Cited by
- 228
- References
- 1
- FWCI
- 6.94
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Silica-Coated Gold Nanostars for Combined Surface-Enhanced Raman Scattering (SERS) Detection and Singlet-Oxygen Generation: A Potential Nanoplatform for Theranostics. https://app.cochat.ai/papers/10.1021/la202602q
- The paper
- Fales, A. M., Yuan, H., & Vo-Dinh, T. (2011). Silica-Coated Gold Nanostars for Combined Surface-Enhanced Raman Scattering (SERS) Detection and Singlet-Oxygen Generation: A Potential Nanoplatform for Theranostics. Langmuir. https://doi.org/10.1021/la202602q
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
