The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Gold Nanocluster-Based Fluorescent Probes for Near-Infrared and Turn-On Sensing of Glutathione in Living Cells
Abstract
In this study, a novel Au nanocluster (NC)-based fluorescent sensor has been designed for near-infrared (NIR) and turn-on sensing of glutathione (GSH) in both living cells and human blood samples. The large Stokes-shifted (140 nm) fluorescent Au NCs with NIR emission and long-wavelength excitation have been rapidly synthesized for 2 h by means of a microwave-assisted method in aqueous solution. The addition of Hg(II) leads to an almost complete emission quenching (98%) of Au NCs because of the interaction of Hg(II) and Au(I) on the surface of Au NCs. After introducing GSH to the Au NC-Hg(II) system, a more than 20 times fluorescent enhancement is obtained because of the preferable affinity of GSH with Hg(II). Under optimum conditions, the fluorescence recovery is linearly proportional to the concentration of GSH between 0.04 and 16.0 μM and the detection limit is as low as 7.0 nM. This Au NC-based sensor with high sensitivity and low spectral interference has been proven to facilitate biosensing applications.
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Cites
Glutathione Deficiency and Human Immunodeficiency Virus Infection
Staal, F. J. T., Ela, S. W., Roederer, M., Anderson, M. T., Herzenberg, L. A., & Herzenberg, L. A. (1992) · The Lancet · doi:10.1016/0140-6736(92)90939-z · Cited by 404
Cheesman, B. V., Arnold, A. P., & Rabenstein, D. L. (1988) · Journal of the American Chemical Society · doi:10.1021/ja00227a014 · Cited by 149
Cited by
Applications of Supramolecular Anion Recognition
Busschaert, N., Caltagirone, C., Van Rossom, W., & Gale, P. A. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00099 · Cited by 1,249
Zhang, X.-L., Zheng, C., Guo, S.-S., Li, J., Yang, H.-H., & Chen, G. (2014) · Analytical Chemistry · doi:10.1021/ac500336f · Cited by 414
Fluorescent nanoparticles for intracellular sensing: A review
Ruedas-Rama, M. J., Walters, J. D., Orte, A., & Hall, E. A. H. (2012) · Analytica Chimica Acta · doi:10.1016/j.aca.2012.09.025 · Cited by 321
Metadata
- Authors
- Tian, D., Qian, Z., Xia, Y., & Zhu, C.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-02-16
- Volume
- 28
- Issue
- 8
- Pages
- 3945-3951
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2069963723
- Cited by
- 173
- References
- 2
- FWCI
- 9.12
- Type
- journal article
- Language
- en
- Open access
- closed
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