Enantiospecific Adsorption of Amino Acids on Hydroxylated Quartz (0001)
Abstract
Density functional theory calculations have been used to study the adsorption of glycine, alanine, serine, and cysteine on the hydroxylated (0001) surface of alpha-quartz. We found negligible differences in adsorption energies for the most stable minima of enantiomers of alanine on this surface. There are, however, measurable energy differences between the two enantiomers of both serine and cysteine in their most stable states. The source of this enantiospecificity is mainly the difference in the strength of hydrogen bonds between the surface and the two enantiomers. Our results provide initial information on how amino acids can exhibit enantiospecific adsorption on hydroxylated quartz surfaces.
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DFT studies show modest computed differences in adsorption energies of enantiomers on quartz (on the order of 2 kcal mol−1 at best).
“In short, the computed differences in the adsorption energies of the enantiomers are modest (on the order of 2 kcal mol À1 at best) but strongly depend on the nature of amino acids and quartz surfaces.”
From Possible chemical and physical scenarios towards biological homochirality (2022) · cites this paper as [253]
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- Authors
- Han, J. W., & Sholl, D. S.
- Affiliations
- Georgia Institute of Technology (US)
- Corresponding author
- Sholl, David S.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-06-04
- Volume
- 25
- Issue
- 18
- Pages
- 10737-10745
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W1964037415
- Cited by
- 37
- References
- 73
- Citations by year
- 2026: 2 · 2024: 1 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 5 · 2014: 3 · 2013: 3 · 2012: 2
- FWCI
- 2.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Langmuir (publishedVersion)
- PubMed (publishedVersion)
- Open Access System for Information Sharing (Pohang University of Science and Technology) (submittedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Surface Chemistry and Catalysis
- Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Advanced Chemical Physics Studies
- Physical Sciences › Chemistry › Spectroscopy › Analytical Chemistry and Chromatography
- Keywords
- amino acids, glycine, alanine, serine, cysteine, enantiomers, hydrogen bonding, adsorption energy, chiral recognition
- MeSH terms
- Adsorption, Alanine, Amino Acids, Cysteine, Glycine, Hydrogen Bonding, Hydroxylation, Models, Molecular, Molecular Conformation, Quantum Theory, Quartz, Serine, Stereoisomerism
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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