The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Combining ATRP and “Click” Chemistry: a Promising Platform toward Functional Biocompatible Polymers and Polymer Bioconjugates
Abstract
The bromine chain-ends of well-defined poly(oligo(ethylene glycol) acrylate) (POEGA) ( M n = 6850 g·mol -1, M w / M n = 1.21) prepared using ATRP were successfully transformed into various functional end groups (ω-hydroxy, ω-amino, and ω-Fmoc-amino acid) via a two step pathway: (1) substitution of the bromine terminal atom by an azide function, (2) 1,3-dipolar cycloaddition of the terminal azide and functional alkynes (propargyl alcohol, propargylamine, and N -α-(9-fluorenylmethyloxycarbonyl)- l -propargylglycine). The efficient “click” cycloaddition was confirmed in all cases by 1 H NMR or SEC−UV analysis. Moreover, this two-step synthetic strategy was also studied for preparing polymer- b -oligopeptide bioconjugates. Well-defined POEGA- b -GGRGDG was obtained in high yields via the “click” ligation of the azido functional POEGA and the alkyne functional oligopeptide GGRGDG.
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Cites
RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINS
Ruoslahti, E. (1996) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.12.1.697 · Cited by 3,191
PEG- and Peptide-Grafted Aliphatic Polyesters by Click Chemistry
Parrish, B., Breitenkamp, R. B., & Emrick, T. (2005) · Journal of the American Chemical Society · doi:10.1021/ja050310n · Cited by 579
Cited by
Ouchi, M., Terashima, T., & Sawamoto, M. (2009) · Chemical Reviews · doi:10.1021/cr900234b · Cited by 1,257
Marrying click chemistry with polymerization: expanding the scope of polymeric materials
Golas, P. L., & Matyjaszewski, K. (2010) · Chem. Soc. Rev. · doi:10.1039/b901978m · Cited by 863
Atrp in the design of functional materials for biomedical applications
Siegwart, D. J., Oh, J. K., & Matyjaszewski, K. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.08.001 · Cited by 613
“Click”‐Chemistry in Polymer and Material Science: the Update
Binder, W. H. (2008) · Macromolecular Rapid Communications · doi:10.1002/marc.200800332 · Cited by 567
Metadata
- Authors
- Lutz, J.-F., Börner, H. G., & Weichenhan, K.
- Venue
- Macromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-08-19
- Volume
- 39
- Issue
- 19
- Pages
- 6376-6383
- ISSN
- 0024-9297 (ISSN-L)
- 1520-5835
- OpenAlex
- W2083881050
- Cited by
- 270
- References
- 2
- FWCI
- 19.14
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lutz, J.-F., Börner, H. G., & Weichenhan, K. (2006). Combining ATRP and “Click” Chemistry: a Promising Platform toward Functional Biocompatible Polymers and Polymer Bioconjugates. Macromolecules. https://doi.org/10.1021/ma061557n
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