Gemcitabine versus Modified Gemcitabine: A Review of Several Promising Chemical Modifications

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Items 101–200 of 232

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7. Polymer coated nanodiamonds as gemcitabine prodrug with enzymatic sensitivity for pancreatic cancer treatment
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9. Amphiphilic Dendritic Nanomicelle-Mediated Delivery of Gemcitabine for Enhancing the Specificity and Effectiveness
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10. Discovery of a novel chimeric ubenimex–gemcitabine with potent oral antitumor activity
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11. Poly(anhydride-ester) gemcitabine: Synthesis and particle engineering of a high payload hydrolysable polymeric drug for cancer therapy
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13. Design, synthesis and antitumor activity study of a gemcitabine prodrug conjugated with a HDAC6 inhibitor
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14. Biological evaluation of novel gemcitabine analog in patient-derived xenograft models of pancreatic cancer
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15. Polymeric Nanoparticles Engineered for Optimal Drug Delivery Using Atomistic Computational Simulation
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16. Development of potent CPP6–gemcitabine conjugates against human prostate cancer cell line (PC-3)
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18. A Diels-Alder polymer platform for thermally enhanced drug release toward efficient local cancer chemotherapy
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19. Self-assembled coumarin- and 5-fluorouracil-PEG micelles as multifunctional drug delivery systems
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21. Pectin based stimuli responsive nanovesicles: A promising strategy for sustained release, and augmenting bioavailability of gemcitabine
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23. The Dipeptide Monoester Prodrugs of Floxuridine and Gemcitabine—Feasibility of Orally Administrable Nucleoside Analogs
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24. Coadministration of Polymeric Conjugates of Docetaxel and Cyclopamine Synergistically Inhibits Orthotopic Pancreatic Cancer Growth and Metastasis
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26. Dual-Face Nucleoside Scaffold Featuring a Stereogenic All-Carbon Quaternary Center. Intramolecular Silicon Tethered Group-Transfer Reaction
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29. Phase I dose escalation and pharmacokinetic evaluation of two different schedules of LY2334737, an oral gemcitabine prodrug, in patients with advanced solid tumors
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33. Vitamin E Phosphate Nucleoside Prodrugs: A Platform for Intracellular Delivery of Monophosphorylated Nucleosides
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34. Design of the New Closo-Dodecarborate-Containing Gemcitabine Analogue for the Albumin-Based Theranostics Composition
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35. The 4-N-acyl and 4-N-alkyl gemcitabine analogues with silicon-fluoride-acceptor: Application to 18F-Radiolabeling
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36. Involvement of CYP4F2 in the Metabolism of a Novel Monophosphate Ester Prodrug of Gemcitabine and Its Interaction Potential In Vitro
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37. Two Possible Strategies for Drug Modification of Gemcitabine and Future Contributions to Personalized Medicine
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40. Therapeutic Use of Fluorinated Nucleosides – Progress in Patents
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41. Electrochemical sensor based on reduced graphene oxide paste electrode for detection of gemcitabine as a chemotherapy drug in breast cancer
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42. LogP of N-acyl-gemcitabine and lectin-corona emerge as key parameters in nanoparticulate intravesical cancer therapy
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44. A Cathepsin B-Sensitive Gemcitabine Prodrug for Enhanced Pancreatic Cancer Therapy
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48. Tumor Microenvironment Modulates Invadopodia Activity of Non-Selected and Acid-Selected Pancreatic Cancer Cells and Its Sensitivity to Gemcitabine and C18-Gemcitabine
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50. Synthesis and in vitro anticancer activity of new gemcitabine-nucleoside analogue dimers containing methyltriazole or ester-methyltriazole linker
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54. Synthesis, anti-HIV and cytostatic evaluation of 3′-deoxy-3′-fluorothymidine (FLT) pro-nucleotides
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55. Dual pH-Responsive Calcium Phosphate Nanoparticles Conjugated with Folate by CuAAC Click Chemistry for Targeted Gemcitabine Delivery to Cancer Cells
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