The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Glucose-Sensitivity of Boronic Acid Block Copolymers at Physiological pH
Abstract
Well-defined boronic acid block copolymers were demonstrated to exhibit glucose-responsive disassembly at physiological pH. A boronic acid-containing acrylamide monomer with an electron-withdrawing substituent on the pendant phenylboronic acid moiety was polymerized by reversible addition–fragmentation chain transfer (RAFT) polymerization to yield a polymer with a boronic acid p K a = 8.2. Below this value, a block copolymer of this monomer with poly( N, N -dimethylacrylamide) self-assembled into aggregates. Addition of base to yield a pH > p K a or addition of glucose at pH = 7.4 resulted in aggregate dissociation that may prove promising for controlled delivery applications under physiological relevant conditions.
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Wang, J.-S., & Matyjaszewski, K. (1995) · Journal of the American Chemical Society · doi:10.1021/ja00125a035 · Cited by 4,622
Kato, M., Kamigaito, M., Sawamoto, M., & Higashimura, T. (1995) · Macromolecules · doi:10.1021/ma00109a056 · Cited by 3,046
Cited by
Expanding the Scope of RAFT Polymerization: Recent Advances and New Horizons
Hill, M. R., Carmean, R. N., & Sumerlin, B. S. (2015) · Macromolecules · doi:10.1021/acs.macromol.5b00342 · Cited by 494
Self-citationBoronic Acid-Based Hydrogels Undergo Self-Healing at Neutral and Acidic pH
Deng, C. C., Brooks, W. L. A., Abboud, K. A., & Sumerlin, B. S. (2015) · ACS Macro Letters · doi:10.1021/acsmacrolett.5b00018 · Cited by 438
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Metadata
- Authors
- Roy, D., & Sumerlin, B. S.
- Venue
- ACS Macro Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-04-09
- Volume
- 1
- Issue
- 5
- Pages
- 529-532
- ISSN
- 2161-1653 (ISSN-L)
- OpenAlex
- W2329542867
- Cited by
- 172
- References
- 2
- FWCI
- 9.33
- Type
- journal article
- Language
- en
- Open access
- closed
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