The DOI matches its Crossref record.
Antigen/Antibody Immunocomplex from CdTe Nanoparticle Bioconjugates
Abstract
Complementary bioconjugates based on antibody−antigen interactions were synthesized from luminescent CdTe nanoparticles (NPs). Antigen (bovine serum albumin) was conjugated to red-emitting CdTe NPs, while green-emitting NPs were attached to the corresponding anti-BSA antibody (IgG). The NP bioconjugates were characterized by native and SDS−PAGE electrophoresis, gel-permeation HPLC, and circular dichroism. Antigen−antibody binding affinity was evaluated by enzyme-linked immunosorbent assay (ELISA). The formation of BSA−IgG immunocomplex resulted in the Förster resonance energy transfer (FRET) between the two different NPs: the luminescence of green-emitting NPs was quenched whereas the emission of the red-emitting NPs was enhanced. The luminescence recovered when the immunocomplex was exposed to an unlabeled antigen. The immunocomplexes can be considered as a prototype of NP superstructures based on biospecific ligands, while the competitive FRET inhibition can be used in an immunoassay protocol.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Nanoparticles: Emerging carriers for drug delivery
Mudshinge, S. R., Deore, A. B., Patil, S., & Bhalgat, C. M. (2011) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2011.04.001 · Cited by 543
de Mello Donegá, C., Liljeroth, P., & Vanmaekelbergh, D. (2005) · Small · doi:10.1002/smll.200500239 · Cited by 511
Optical molecular sensing with semiconductor quantum dots (QDs)
Freeman, R., & Willner, I. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15357b · Cited by 485
Biosensing with Luminescent Semiconductor Quantum Dots
Sapsford, K. E., Pons, T., Medintz, I. L., & Mattoussi, H. (2006) · Sensors · doi:10.3390/s6080925 · Cited by 420
Yousefi, M., Dadashpour, M., Hejazi, M., Hasanzadeh, M., Behnam, B., de la Guardia, M., Shadjou, N., & Mokhtarzadeh, A. (2017) · Materials Science and Engineering: C · doi:10.1016/j.msec.2016.12.125 · Cited by 258
Metadata
- Authors
- Wang, S., Mamedova, N., Kotov, N. A., Chen, W., & Studer, J.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2002-07-19
- Volume
- 2
- Issue
- 8
- Pages
- 817-822
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2012099438
- Cited by
- 529
- References
- 0
- FWCI
- 11.70
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Antigen/Antibody Immunocomplex from CdTe Nanoparticle Bioconjugates. https://app.cochat.ai/papers/10.1021/nl0255193
- The paper
- Wang, S., Mamedova, N., Kotov, N. A., Chen, W., & Studer, J. (2002). Antigen/Antibody Immunocomplex from CdTe Nanoparticle Bioconjugates. Nano Letters. https://doi.org/10.1021/nl0255193
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
