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Biosensing with Luminescent Semiconductor Quantum Dots
Open accessAbstract
Luminescent semiconductor nanocrystals or quantum dots (QDs) are a recentlydeveloped class of nanomaterial whose unique photophysical properties are helping tocreate a new generation of robust fluorescent biosensors. QD properties of interest forbiosensing include high quantum yields, broad absorption spectra coupled to narrow sizetunablephotoluminescent emissions and exceptional resistance to both photobleaching andchemical degradation. In this review, we examine the progress in adapting QDs for severalpredominantly in vitro biosensing applications including use in immunoassays, asgeneralized probes, in nucleic acid detection and fluorescence resonance energy transfer(FRET) - based sensing. We also describe several important considerations when workingwith QDs mainly centered on the choice of material(s) and appropriate strategies forattaching biomolecules to the QDs.
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Dabbousi, B. O., Rodriguez-Viejo, J., Mikulec, F. V., Heine, J. R., Mattoussi, H., Ober, R., Jensen, K. F., & Bawendi, M. G. (1997) · The Journal of Physical Chemistry B · doi:10.1021/jp971091y · Cited by 4,229
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Quantum Dots and Their Multimodal Applications: A Review
Bera, D., Qian, L., Tseng, T.-K., & Holloway, P. H. (2010) · Materials · doi:10.3390/ma3042260 · Cited by 1,365
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Baruah, A., Chaudhary, V., Malik, R., & Tomer, V. K. (2019) · Nanotechnology in Water and Wastewater Treatment · doi:10.1016/b978-0-12-813902-8.00017-4 · Cited by 121
Maxwell, T., Nogueira Campos, M. G., Smith, S., Doomra, M., Thwin, Z., & Santra, S. (2020) · Nanoparticles for Biomedical Applications · doi:10.1016/b978-0-12-816662-8.00015-1 · Cited by 43
Metadata
- Authors
- Sapsford, K. E., Pons, T., Medintz, I. L., & Mattoussi, H.
- Venue
- Sensors
- Publisher
- MDPI AG
- Published
- 2006-08-24
- Volume
- 6
- Issue
- 8
- Pages
- 925-953
- ISSN
- 1424-8220 (ISSN-L)
- OpenAlex
- W2155193757
- Cited by
- 420
- References
- 1
- FWCI
- 14.76
- Type
- journal article
- Language
- en
- Open access
- gold
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- Sapsford, K. E., Pons, T., Medintz, I. L., & Mattoussi, H. (2006). Biosensing with Luminescent Semiconductor Quantum Dots. Sensors. https://doi.org/10.3390/s6080925
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