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Self-Assembled Peptide Amphiphile Nanofibers Conjugated to MRI Contrast Agents
Abstract
Self-assembled peptide amphiphile nanofibers have been investigated for their potential use as in vivo scaffolds for tissue engineering and drug delivery applications. We report here the synthesis of magnetic resonance (MR) active peptide amphiphile molecules that self-assemble into spherical and fiber-like nanostructures, enhancing T(1) relaxation time. This new class of MR contrast agents can potentially be used to combine high-resolution three-dimensional MR fate mapping of tissue-engineered scaffolds with targeting of specific cellular receptors.
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Cited by
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Slaughter, B. V., Khurshid, S. S., Fisher, O. Z., Khademhosseini, A., & Peppas, N. A. (2009) · Advanced Materials · doi:10.1002/adma.200802106 · Cited by 2,703
Metal- and Anion-Binding Supramolecular Gels
Piepenbrock, M.-O. M., Lloyd, G. O., Clarke, N., & Steed, J. W. (2010) · Chemical Reviews · doi:10.1021/cr9003067 · Cited by 1,199
Rheological properties of peptide-based hydrogels for biomedical and other applications
Yan, C., & Pochan, D. J. (2010) · Chemical Society Reviews · doi:10.1039/b919449p · Cited by 800
One dimensional nanostructured materials
Kuchibhatla, S. V. N. T., Karakoti, A. S., Bera, D., & Seal, S. (2007) · Progress in Materials Science · doi:10.1016/j.pmatsci.2006.08.001 · Cited by 631
A Review on the Synthesis and Functionalization of Gold Nanoparticles as a Drug Delivery Vehicle
Amina, S. J., & Guo, B. (2020) · International Journal of Nanomedicine · doi:10.2147/ijn.s279094 · Cited by 561
Metadata
- Authors
- Bull, S. R., Guler, M. O., Bras, R. E., Meade, T. J., & Stupp, S. I.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-12-09
- Volume
- 5
- Issue
- 1
- Pages
- 1-4
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2056430909
- Cited by
- 237
- References
- 0
- FWCI
- 5.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bull, S. R., Guler, M. O., Bras, R. E., Meade, T. J., & Stupp, S. I. (2005). Self-Assembled Peptide Amphiphile Nanofibers Conjugated to MRI Contrast Agents. Nano Letters. https://doi.org/10.1021/nl0484898
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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