The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Fast DNA Sequencing via Transverse Electronic Transport
Open accessAbstract
A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of single-stranded DNA while it translocates through a nanopore. Our estimates, based on the statistics of these distributions, reveal that sequencing of an entire human genome could be done with very high accuracy in a matter of hours without parallelization, that is, orders of magnitude faster than present techniques. The practical implementation of our approach would represent a substantial advancement in our ability to study, predict, and cure diseases from the perspective of the genetic makeup of each individual.
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Citations
Cites
A vision for the future of genomics research
Collins, F. S., Green, E. D., Guttmacher, A. E., Guyer, M. S., & on behalf of the US National Human Genome Research Institute (2003) · Nature · doi:10.1038/nature01626 · Cited by 1,752
Cited by
Nanopore sensors for nucleic acid analysis
Venkatesan, B. M., & Bashir, R. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.129 · Cited by 1,302
Identification of single nucleotides in MoS2 nanopores
Feng, J., Liu, K., Bulushev, R. D., Khlybov, S., Dumcenco, D., Kis, A., & Radenovic, A. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2015.219 · Cited by 512
Colloquium: Physical approaches to DNA sequencing and detection
Zwolak, M., & Di Ventra, M. (2008) · Reviews of Modern Physics · doi:10.1103/revmodphys.80.141 · Cited by 457
Self-citationRapid Sequencing of Individual DNA Molecules in Graphene Nanogaps
Postma, H. W. C. (2010) · Nano Letters · doi:10.1021/nl9029237 · Cited by 375
Interface chemistry of two-dimensional heterostructures – fundamentals to applications
Gbadamasi, S., Mohiuddin, M., Krishnamurthi, V., Verma, R., Khan, M. W., Pathak, S., Kalantar-Zadeh, K., & Mahmood, N. (2021) · Chemical Society Reviews · doi:10.1039/d0cs01070g · Cited by 304
(2007) · Cited by 33
Metadata
- Authors
- Lagerqvist, J., Zwolak, M., & Di Ventra, M.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-03-11
- Volume
- 6
- Issue
- 4
- Pages
- 779-782
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1990968510
- Cited by
- 404
- References
- 1
- FWCI
- 21.45
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.