The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Identification of single nucleotides in MoS2 nanopores
Open accessAbstract
The size of the sensing region in solid-state nanopores is determined by the size of the pore and the thickness of the pore membrane, so ultrathin membranes such as graphene and single-layer molybdenum disulphide could potentially offer the necessary spatial resolution for nanopore DNA sequencing. However, the fast translocation speeds (3,000-50,000 nt ms(-1)) of DNA molecules moving across such membranes limit their usability. Here, we show that a viscosity gradient system based on room-temperature ionic liquids can be used to control the dynamics of DNA translocation through MoS2 nanopores. The approach can be used to statistically detect all four types of nucleotide, which are identified according to current signatures recorded during their transient residence in the narrow orifice of the atomically thin MoS2 nanopore. Our technique, which exploits the high viscosity of room-temperature ionic liquids, provides optimal single nucleotide translocation speeds for DNA sequencing, while maintaining a signal-to-noise ratio higher than 10.
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Self-citationCharacterization of individual polynucleotide molecules using a membrane channel
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Grains and grain boundaries in highly crystalline monolayer molybdenum disulphide
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Graphene as a subnanometre trans-electrode membrane
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Nanopore sensors for nucleic acid analysis
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DNA Translocation through Graphene Nanopores
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Cited by
2D materials as an emerging platform for nanopore-based power generation
Macha, M., Marion, S., Nandigana, V. V. R., & Radenovic, A. (2019) · Nature Reviews Materials · doi:10.1038/s41578-019-0126-z · Cited by 426
Self-citationSingle-molecule protein sensing in a nanopore: a tutorial
Varongchayakul, N., Song, J., Meller, A., & Grinstaff, M. W. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00106e · Cited by 282
Digital Data Storage Using DNA Nanostructures and Solid-State Nanopores
Chen, K., Kong, J., Zhu, J., Ermann, N., Predki, P., & Keyser, U. F. (2019) · Nano Letters · doi:10.1021/acs.nanolett.8b04715 · Cited by 164
Wang, Y., Zhang, S., Jia, W., Fan, P., Wang, L., Li, X., Chen, J., Cao, Z., Du, X., Liu, Y., et al. (2022) · Nature Nanotechnology · doi:10.1038/s41565-022-01169-2 · Cited by 143
Metadata
- Authors
- Feng, J., Liu, K., Bulushev, R. D., Khlybov, S., Dumcenco, D., Kis, A., & Radenovic, A.
- Venue
- Nature Nanotechnology
- Published
- 2015-09-21
- Volume
- 10
- Issue
- 12
- Pages
- 1070-1076
- ISSN
- 1748-3387 (ISSN-L)
- 1748-3395
- OpenAlex
- W1942871038
- Cited by
- 512
- References
- 45
- FWCI
- 21.23
- Type
- journal article
- Language
- en
- Open access
- green
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