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Cited by 512

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Identification of single nucleotides in MoS2 nanopores

Open access
Feng, Jiandong, Liu, Ke, Bulushev, Roman D., Khlybov, Sergey, Dumcenco, Dumitru, Kis, Andras, Radenovic, Aleksandra·2015·Nature Nanotechnology

Abstract

The size of the sensing region in solid-state nanopores is determined by the size of the pore and the thickness of the pore membrane, so ultrathin membranes such as graphene and single-layer molybdenum disulphide could potentially offer the necessary spatial resolution for nanopore DNA sequencing. However, the fast translocation speeds (3,000-50,000 nt ms(-1)) of DNA molecules moving across such membranes limit their usability. Here, we show that a viscosity gradient system based on room-temperature ionic liquids can be used to control the dynamics of DNA translocation through MoS2 nanopores. The approach can be used to statistically detect all four types of nucleotide, which are identified according to current signatures recorded during their transient residence in the narrow orifice of the atomically thin MoS2 nanopore. Our technique, which exploits the high viscosity of room-temperature ionic liquids, provides optimal single nucleotide translocation speeds for DNA sequencing, while maintaining a signal-to-noise ratio higher than 10.

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Metadata

Authors
Feng, J., Liu, K., Bulushev, R. D., Khlybov, S., Dumcenco, D., Kis, A., & Radenovic, A.
Venue
Nature Nanotechnology
Published
2015-09-21
Volume
10
Issue
12
Pages
1070-1076
ISSN
  • 1748-3387 (ISSN-L)
  • 1748-3395
OpenAlex
W1942871038
Cited by
512
References
45
FWCI
21.23
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Identification of single nucleotides in MoS2 nanopores. https://app.cochat.ai/papers/10.1038/nnano.2015.219
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Feng, J., Liu, K., Bulushev, R. D., Khlybov, S., Dumcenco, D., Kis, A., & Radenovic, A. (2015). Identification of single nucleotides in MoS2 nanopores. Nature Nanotechnology. https://doi.org/10.1038/nnano.2015.219

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