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Nanoparticles for Two-Photon Photodynamic Therapy in Living Cells
Open accessAbstract
We describe here a nontoxic two-photon photodynamic nanoparticle platform and its cellular application. We demonstrate that the dye's potential toxicity can be circumvented by its permanent encapsulation into a biocompatible nanoparticle polymer matrix; this was examined by dye leaching experiments and confirmed by cell uptake experiments. Infrared two-photon nanoplatform phototoxicity was demonstrated for rat C6 glioma cells, while the controls showed no dark toxicity for these living cells.
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Cited by
Photosensitizers with Aggregation‐Induced Emission: Materials and Biomedical Applications
Hu, F., Xu, S., & Liu, B. (2018) · Advanced Materials · doi:10.1002/adma.201801350 · Cited by 859
Nanoparticles as vehicles for delivery of photodynamic therapy agents
Bechet, D., Couleaud, P., Frochot, C., Viriot, M.-L., Guillemin, F., & Barberi-Heyob, M. (2008) · Trends in Biotechnology · doi:10.1016/j.tibtech.2008.07.007 · Cited by 760
Ohulchanskyy, T. Y., Roy, I., Goswami, L. N., Chen, Y., Bergey, E. J., Pandey, R. K., Oseroff, A. R., & Prasad, P. N. (2007) · Nano Letters · doi:10.1021/nl0714637 · Cited by 329
Biodegradable, polymeric nanoparticle delivery systems for cancer therapy
Pridgen, E. M., Langer, R., & Farokhzad, O. C. (2007) · Nanomedicine · doi:10.2217/17435889.2.5.669 · Cited by 249
Metadata
- Authors
- Gao, D., Agayan, R. R., Xu, H., Philbert, M. A., & Kopelman, R.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-10-24
- Volume
- 6
- Issue
- 11
- Pages
- 2383-2386
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2011525841
- Cited by
- 211
- References
- 0
- FWCI
- 10.73
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Nanoparticles for Two-Photon Photodynamic Therapy in Living Cells. https://app.cochat.ai/papers/10.1021/nl0617179
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- Gao, D., Agayan, R. R., Xu, H., Philbert, M. A., & Kopelman, R. (2006). Nanoparticles for Two-Photon Photodynamic Therapy in Living Cells. Nano Letters. https://doi.org/10.1021/nl0617179
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
