The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity
Abstract
Genotoxicity of commercial colloidal and laboratory-synthesized silica nanoparticles was tested using the single cell gel electrophoresis or Comet assay. By using a carefully developed protocol and careful characterization of the nanoparticle dispersions, Comet assays were performed on 3T3-L1 fibroblasts with 3, 6, and 24 h incubations and 4 or 40 microg/ml of silica nanoparticles. No significant genotoxicity was observed for the nanoparticles tested under the conditions described, and results were independently validated in two separate laboratories, showing that in vitro toxicity testing can be quantitatively reproducible.
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Brunner, T. J., Wick, P., Manser, P., Spohn, P., Grass, R. N., Limbach, L. K., Bruinink, A., & Stark, W. J. (2006) · Environmental Science & Technology · doi:10.1021/es052069i · Cited by 1,385
Cytotoxicity and DNA-damage in human lung epithelial cells exposed to respirable α-quartz
Fanizza, C., Ursini, C. L., Paba, E., Ciervo, A., Di Francesco, A., Maiello, R., De Simone, P., & Cavallo, D. (2007) · Toxicology in Vitro · doi:10.1016/j.tiv.2006.12.002 · Cited by 44
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Magdolenova, Z., Collins, A., Kumar, A., Dhawan, A., Stone, V., & Dusinska, M. (2014) · Nanotoxicology · doi:10.3109/17435390.2013.773464 · Cited by 616
Analytical methods to assess nanoparticle toxicity
Marquis, B. J., Love, S. A., Braun, K. L., & Haynes, C. L. (2009) · The Analyst · doi:10.1039/b818082b · Cited by 406
Nanomaterials in food and agriculture: An overview on their safety concerns and regulatory issues
Jain, A., Ranjan, S., Dasgupta, N., & Ramalingam, C. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2016.1160363 · Cited by 367
Biocompatibility and Toxicity of Nanoparticles and Nanotubes
Li, X., Wang, L., Fan, Y., Feng, Q., & Cui, F.-Z. (2012) · Journal of Nanomaterials · doi:10.1155/2012/548389 · Cited by 351
Physico-chemical features of engineered nanoparticles relevant to their toxicity
Fubini, B., Ghiazza, M., & Fenoglio, I. (2010) · Nanotoxicology · doi:10.3109/17435390.2010.509519 · Cited by 297
Metadata
- Authors
- Barnes, C. A., Elsaesser, A., Arkusz, J., Smok, A., Palus, J., Leśniak, A., Salvati, A., Hanrahan, J. P., Jong, W. H. D., Dziubałtowska, E., Stȩpnik, M., Rydzyński, K., McKerr, G., Lynch, I., Dawson, K. A., & Howard, C. V.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-08-12
- Volume
- 8
- Issue
- 9
- Pages
- 3069-3074
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1968749227
- Cited by
- 226
- References
- 2
- FWCI
- 5.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- Barnes, C. A., Elsaesser, A., Arkusz, J., Smok, A., Palus, J., Leśniak, A., Salvati, A., Hanrahan, J. P., Jong, W. H. D., Dziubałtowska, E., Stȩpnik, M., Rydzyński, K., McKerr, G., Lynch, I., Dawson, K. A., & Howard, C. V. (2008). Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity. Nano Letters. https://doi.org/10.1021/nl801661w
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
