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High-Efficiency Upconversion Luminescent Sensing and Bioimaging of Hg(II) by Chromophoric Ruthenium Complex-Assembled Nanophosphors
Abstract
A chromophoric ruthenium complex-assembled nanophosphor (N719-UCNPs) was achieved as a highly selective water-soluble probe for upconversion luminescence sensing and bioimaging of intracellular mercury ions. The prepared nanophosphors were characterized by X-ray powder diffraction (XRD), transmission electron microscopy (TEM), energy-dispersive X-ray analysis (EDXA), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). Further application of N719-UCNPs in sensing Hg(2+) was confirmed by optical titration experiment and upconversion luminescence live cell imaging. Using the ratiometric upconversion luminescence as a detection signal, the detection limit of Hg(2+) for this nanoprobe in water was down to 1.95 ppb, lower than the maximum level (2 ppb) of Hg(2+) in drinking water set by the United States EPA. Importantly, the nanoprobe N719-UCNPs has been shown to be capable of monitoring changes in the distribution of Hg(2+) in living cells by upconversion luminescence bioimaging.
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(1999) · Choice Reviews Online · doi:10.5860/choice.37-0940 · Cited by 14,314
Cited by
Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
Chen, G., Qiu, H., Prasad, P. N., & Chen, X. (2014) · Chemical Reviews · doi:10.1021/cr400425h · Cited by 2,699
Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy
Chen, G., Roy, I., Yang, C., & Prasad, P. N. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00148 · Cited by 1,499
Ratiometric optical nanoprobes enable accurate molecular detection and imaging
Huang, X., Song, J., Yung, B. C., Huang, X., Xiong, Y., & Chen, X. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00612h · Cited by 820
Li, X., Zhang, F., & Zhao, D. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00163j · Cited by 615
Nanostructured Sensors for Detection of Heavy Metals: A Review
Li, M., Gou, H., Al-Ogaidi, I., & Wu, N. (2013) · ACS Sustainable Chemistry & Engineering · doi:10.1021/sc400019a · Cited by 606
Metadata
- Authors
- Liu, Q., Peng, J., Sun, L., & Li, F.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-09-13
- Volume
- 5
- Issue
- 10
- Pages
- 8040-8048
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2323755728
- Cited by
- 263
- References
- 1
- FWCI
- 14.25
- Type
- journal article
- Language
- en
- Open access
- closed
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