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Halloysite Clay Nanotubes for Controlled Release of Protective Agents
Abstract
Halloysite aluminosilicate nanotubes with a 15 nm lumen, 50 nm external diameter, and length of 800 +/- 300 nm have been developed as an entrapment system for loading, storage, and controlled release of anticorrosion agents and biocides. Fundamental research to enable the control of release rates from hours to months is being undertaken. By variation of internal fluidic properties, the formation of nanoshells over the nanotubes and by creation of smart caps at the tube ends it is possible to develop further means of controlling the rate of release. Anticorrosive halloysite coatings are in development and a self-healing approach has been developed for repair mechanisms through response activation to external impacts. In this Perspective, applications of halloysite as nanometer-scale containers are discussed, including the use of halloysite tubes as drug releasing agents, as biomimetic reaction vessels, and as additives in biocide and protective coatings. Halloysite nanotubes are available in thousands of tons, and remain sophisticated and novel natural nanomaterials which can be used for the loading of agents for metal and plastic anticorrosion and biocide protection.
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Cited by
Challenges and Recent Progress in Oral Drug Delivery Systems for Biopharmaceuticals
Homayun, B., Lin, X., & Choi, H.-J. (2019) · Pharmaceutics · doi:10.3390/pharmaceutics11030129 · Cited by 837
Elastomeric biomaterials for tissue engineering
Chen, Q., Liang, S., & Thouas, G. A. (2013) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.05.003 · Cited by 564
Yah, W. O., Takahara, A., & Lvov, Y. M. (2012) · Journal of the American Chemical Society · doi:10.1021/ja210258y · Cited by 429
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Metadata
- Authors
- Lvov, Y. M., Shchukin, D. G., Möhwald, H., & Price, R. R.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-05-01
- Volume
- 2
- Issue
- 5
- Pages
- 814-820
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W1983653920
- Cited by
- 934
- References
- 0
- FWCI
- 6.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Halloysite Clay Nanotubes for Controlled Release of Protective Agents. https://app.cochat.ai/papers/10.1021/nn800259q
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- Lvov, Y. M., Shchukin, D. G., Möhwald, H., & Price, R. R. (2008). Halloysite Clay Nanotubes for Controlled Release of Protective Agents. ACS Nano. https://doi.org/10.1021/nn800259q
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.