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Fluorescence Enhancement by Au Nanostructures: Nanoshells and Nanorods

Bardhan, Rizia, Grady, Nathaniel K., Cole, Joseph R., Joshi, Amit, Halas, Naomi J.·2009·ACS Nano

Abstract

Metallic nanoparticles influence the quantum yield and lifetime of adjacent fluorophores in a manner dependent on the properties of the nanostructure. Here we directly compare the fluorescence enhancement of the near-infrared fluorophore IR800 by Au nanoshells (NSs) and Au nanorods (NRs), where human serum albumin (HSA) serves as a spacer layer between the nanoparticle and the fluorophore. Our measurements reveal that the quantum yield of IR800 is enhanced from approximately 7% as an isolated fluorophore to 86% in a NSs-HSA-IR800 complex and 74% in a NRs-HSA-IR800 complex. This dramatic increase in fluorescence shows tremendous potential for contrast enhancement in fluorescence-based bioimaging.

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Metadata

Authors
Bardhan, R., Grady, N. K., Cole, J. R., Joshi, A., & Halas, N. J.
Venue
ACS Nano
Published
2009-02-20
Volume
3
Issue
3
Pages
744-752
ISSN
  • 1936-0851 (ISSN-L)
  • 1936-086X
OpenAlex
W2050527686
Cited by
617
References
3
FWCI
20.82
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Fluorescence Enhancement by Au Nanostructures: Nanoshells and Nanorods. https://app.cochat.ai/papers/10.1021/nn900001q
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Bardhan, R., Grady, N. K., Cole, J. R., Joshi, A., & Halas, N. J. (2009). Fluorescence Enhancement by Au Nanostructures: Nanoshells and Nanorods. ACS Nano. https://doi.org/10.1021/nn900001q

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.