The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
A Predictive Toxicological Paradigm for the Safety Assessment of Nanomaterials
Abstract
The rate of expansion of nanomaterials calls for the consideration of appropriate toxicological paradigms in the safety assessment of nanomaterials. We advocate a predictive toxicological paradigm for the assessment of nanomaterial hazards. The predictive toxicological approach is defined as establishing and using mechanisms and pathways of injury at a cellular and molecular level to prioritize screening for adverse biological effects and health outcomes in vivo. Specifically as it relates to nanomaterials, a predictive approach has to consider the physicochemical properties of the material that leads to molecular or cellular injury and also has to be valid in terms of disease pathogenesis in whole organisms.
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Citations
Cites
Toxic potential of materials at the nanolevel
Nel, A., Xia, T., Mädler, L., & Li, N. (2006) · Science · doi:10.1126/science.1114397 · Cited by 9,324
Self-citationNanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles
Oberdörster, G., Oberdörster, E., & Oberdörster, J. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7339 · Cited by 7,891
Understanding biophysicochemical interactions at the nano–bio interface
Nel, A. E., Mädler, L., Velegol, D., Xia, T., Hoek, E. M. V., Somasundaran, P., Klaessig, F., Castranova, V., & Thompson, M. (2009) · Nature Materials · doi:10.1038/nmat2442 · Cited by 7,083
Self-citationCytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells
AshaRani, P. V., Low Kah Mun, G., Hande, M. P., & Valiyaveettil, S. (2009) · ACS Nano · doi:10.1021/nn800596w · Cited by 3,692
Poland, C. A., Duffin, R., Kinloch, I., Maynard, A., Wallace, W. A. H., Seaton, A., Stone, V., Brown, S., MacNee, W., & Donaldson, K. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2008.111 · Cited by 2,645
Xia, T., Kovochich, M., Liong, M., Mädler, L., Gilbert, B., Shi, H., Yeh, J. I., Zink, J. I., & Nel, A. E. (2008) · ACS Nano · doi:10.1021/nn800511k · Cited by 2,469
Self-citationThe potential environmental impact of engineered nanomaterials
Colvin, V. L. (2003) · Nature Biotechnology · doi:10.1038/nbt875 · Cited by 2,158
Oberdörster, G., Maynard, A., Donaldson, K., Castranova, V., Fitzpatrick, J., Ausman, K., Carter, J., Karn, B., Kreyling, W., Lai, D., et al. (2005) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-2-8 · Cited by 2,134
Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage
Li, N., Sioutas, C., Cho, A., Schmitz, D., Misra, C., Sempf, J., Wang, M., Oberley, T., Froines, J., & Nel, A. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.6000 · Cited by 2,097
Self-citationXia, T., Kovochich, M., Brant, J., Hotze, M., Sempf, J., Oberley, T., Sioutas, C., Yeh, J. I., Wiesner, M. R., & Nel, A. E. (2006) · Nano Letters · doi:10.1021/nl061025k · Cited by 1,918
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Cited by
QSAR Modeling: Where have you been? Where are you going to?
Cherkasov, A., Muratov, E. N., Fourches, D., Varnek, A., Baskin, I. I., Cronin, M., Dearden, J., Gramatica, P., Martin, Y. C., Todeschini, R., et al. (2014) · Journal of Medicinal Chemistry · doi:10.1021/jm4004285 · Cited by 2,164
Toxicity of Nanomaterials: Exposure, Pathways, Assessment, and Recent Advances
Ganguly, P., Breen, A., & Pillai, S. C. (2018) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b00068 · Cited by 341
George, S., Xia, T., Rallo, R., Zhao, Y., Ji, Z., Lin, S., Wang, X., Zhang, H., France, B., Schoenfeld, D., et al. (2011) · ACS Nano · doi:10.1021/nn102734s · Cited by 326
Self-citationCytotoxicity and mitochondrial damage caused by silica nanoparticles
Sun, L., Li, Y., Liu, X., Jin, M., Zhang, L., Du, Z., Guo, C., Huang, P., & Sun, Z. (2011) · Toxicology in Vitro · doi:10.1016/j.tiv.2011.06.012 · Cited by 263
Thickness of Multiwalled Carbon Nanotubes Affects Their Lung Toxicity
Fenoglio, I., Aldieri, E., Gazzano, E., Cesano, F., Colonna, M., Scarano, D., Mazzucco, G., Attanasio, A., Yakoub, Y., Lison, D., et al. (2012) · Chemical Research in Toxicology · doi:10.1021/tx200255h · Cited by 128
Metadata
- Authors
- Meng, H., Xia, T., George, S., & Nel, A. E.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-07-28
- Volume
- 3
- Issue
- 7
- Pages
- 1620-1627
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2046309168
- Cited by
- 344
- References
- 38
- FWCI
- 12.44
- Type
- journal article
- Language
- en
- Open access
- closed
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