The DOI matches its Crossref record.
Anti-AIDS Agents. 48. Anti-HIV Activity of Moronic Acid Derivatives and the New Melliferone-Related Triterpenoid Isolated from Brazilian Propolis
Abstract
A new triterpenoid named melliferone (1), three known triterpenoids, moronic acid (2), anwuweizonic acid (3), and betulonic acid (4), and four known aromatic compounds (5-8) were isolated from Brazilian propolis and tested for anti-HIV activity in H9 lymphocytes. Moronic acid (2) showed significant anti-HIV activity (EC(50) <0.1 microg/mL, TI >186) and was modified to develop more potent anti-AIDS agents.
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Citations
Cited by
Recent advances in the chemical composition of propolis
Huang, S., Zhang, C.-P., Wang, K., Li, G., & Hu, F.-L. (2014) · Molecules · doi:10.3390/molecules191219610 · Cited by 765
Recent trends and important developments in propolis research
Bankova, V. (2005) · Evidence-Based Complementary and Alternative Medicine · doi:10.1093/ecam/neh059 · Cited by 569
Recent Progress of Propolis for Its Biological and Chemical Compositions and Its Botanical Origin
Toreti, V. C., Sato, H. H., Pastore, G. M., & Park, Y. K. (2013) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2013/697390 · Cited by 481
Self-citationSilva-Carvalho, R., Baltazar, F., & Almeida-Aguiar, C. (2015) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2015/206439 · Cited by 333
Brazilian Red Propolis—Chemical Composition and Botanical Origin
Daugsch, A., Moraes, C. S., Fort, P., & Park, Y. K. (2008) · Evidence-Based Complementary and Alternative Medicine · doi:10.1093/ecam/nem057 · Cited by 331
Self-citationLee, K.-H. (2010) · Journal of Natural Products · doi:10.1021/np900821e · Cited by 278
Self-citationPropolis and its potential against SARS-CoV-2 infection mechanisms and COVID-19 disease
Berretta, A. A., Silveira, M. A. D., Cóndor Capcha, J. M., & De Jong, D. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110622 · Cited by 269
Antiviral Activity and Mode of Action of Propolis Extracts and Selected Compounds
Schnitzler, P., Neuner, A., Nolkemper, S., Zundel, C., Nowack, H., Sensch, K. H., & Reichling, J. (2010) · Phytotherapy Research · doi:10.1002/ptr.2868 · Cited by 253
Metadata
- Authors
- Ito, J., Chang, F.-R., Wang, H.-K., Park, Y. K., Ikegaki, M., Kilgore, N., & Lee, K.-H.
- Venue
- Journal of Natural Products
- Publisher
- American Chemical Society (ACS)
- Published
- 2001-09-28
- Volume
- 64
- Issue
- 10
- Pages
- 1278-1281
- ISSN
- 0163-3864 (ISSN-L)
- 1520-6025
- OpenAlex
- W2095735547
- Cited by
- 259
- References
- 0
- FWCI
- 1.19
- Type
- journal article
- Language
- en
- Open access
- closed
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