The DOI matches its Crossref record.
Bioactive Metabolites from a Marine-Derived Strain of the Fungus Emericella variecolor
Abstract
From a marine-derived strain of the fungus Emericella variecolor, varitriol (1), varioxirane (2), dihydroterrein (3), and varixanthone (4), besides the known mold metabolites ergosterol, terrein, shamixanthone, and tajixanthone hydrate, were identified. The chemical structures of 1-4 were established by means of spectroscopic techniques and some chemical transformations. In the NCI's 60-cell panel, varitriol (1) displayed increased potency toward selected renal, CNS, and breast cancer cell lines. Varixanthone (4) showed antimicrobial activity.
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Citations
Cited by
Marine-derived fungi: a chemically and biologically diverse group of microorganisms
Bugni, T. S., & Ireland, C. M. (2004) · Natural Product Reports · doi:10.1039/b301926h · Cited by 760
Blunt, J. W., Copp, B. R., Hu, W.-P., Munro, M. H. G., Northcote, P. T., & Prinsep, M. R. (2008) · Natural Product Reports · doi:10.1039/b701534h · Cited by 365
Marine natural products of fungal origin
Saleem, M., Ali, M. S., Hussain, S., Jabbar, A., Ashraf, M., & Lee, Y. S. (2007) · Natural Product Reports · doi:10.1039/b607254m · Cited by 326
Bhadury, P., Mohammad, B. T., & Wright, P. C. (2006) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-005-0070-3 · Cited by 250
Metadata
- Authors
- Malmstrøm, J., Christophersen, C., Barrero, A. F., Oltra, J. E., Justicia, J., & Rosales, A.
- Venue
- Journal of Natural Products
- Publisher
- American Chemical Society (ACS)
- Published
- 2002-03-01
- Volume
- 65
- Issue
- 3
- Pages
- 364-367
- ISSN
- 0163-3864 (ISSN-L)
- 1520-6025
- OpenAlex
- W2131726253
- Cited by
- 174
- References
- 0
- FWCI
- 2.24
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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