The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Induced Production of Emericellamides A and B from the Marine-Derived Fungus Emericella sp. in Competing Co-culture
Abstract
Induction of the production of emericellamides A and B (1, 2), by the marine-derived fungus Emericella sp., was observed during co-culture with the marine actinomycete Salinispora arenicola. The planar structures of these new cyclic depsipeptides, which incorporate 3-hydroxy-2,4-dimethyldecanoic acid and 3-hydroxy-2,4,6-trimethyldodecanoic acid, were assigned by combined chemical and spectral methods. The absolute configurations of the amino acids, and those of the chiral centers on the side chain, were established by application of the Marfey's method, by J-based configuration analysis, and by application of the modified Mosher method. Emericellamides A and B show modest antibacterial activities against methicillin-resistant Staphylococcus aureus with MIC values of 3.8 and 6.0 microM, respectively.
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Citations
Cites
The role of natural product chemistry in drug discovery
Butler, M. S. (2004) · Journal of Natural Products · doi:10.1021/np040106y · Cited by 1,381
Cited by
Faulkner, D. J. (1990) · Natural Product Reports · doi:10.1039/np9900700269 · Cited by 4,866
Fungal secondary metabolites – Strategies to activate silent gene clusters
Brakhage, A. A., & Schroeckh, V. (2011) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2010.04.004 · Cited by 729
Schroeckh, V., Scherlach, K., Nützmann, H.-W., Shelest, E., Schmidt-Heck, W., Schuemann, J., Martin, K., Hertweck, C., & Brakhage, A. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901870106 · Cited by 663
Blunt, J. W., Copp, B. R., Hu, W.-P., Munro, M. H. G., Northcote, P. T., & Prinsep, M. R. (2009) · Natural Product Reports · doi:10.1039/b805113p · Cited by 520
Blunt, J. W., Copp, B. R., Munro, M. H. G., Northcote, P. T., & Prinsep, M. R. (2011) · Nat. Prod. Rep. · doi:10.1039/c005001f · Cited by 470
Metadata
- Authors
- Oh, D.-C., Kauffman, C. A., Jensen, P. R., & Fenical, W.
- Venue
- Journal of Natural Products
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-02-27
- Volume
- 70
- Issue
- 4
- Pages
- 515-520
- ISSN
- 0163-3864 (ISSN-L)
- 1520-6025
- OpenAlex
- W1980713037
- Cited by
- 286
- References
- 1
- FWCI
- 5.68
- Type
- journal article
- Language
- en
- Open access
- closed
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