The DOI matches its Crossref record.
Synergistic Effect of Flavones and Flavonols Against Herpes Simplex Virus Type 1 in Cell Culture. Comparison with the Antiviral Activity of Propolis
Abstract
The in vitro activity against herpes simplex virus type 1 of the major flavonoids identified in propolis was investigated. Flavonols were found to be more active than flavones, the order of importance being galangin, kaempferol, and quercetin. The efficacy against HSV-1 of binary flavone-flavonol combinations has been also investigated. The synergy demonstrated by all combinations could explain why propolis is more active than its individual compounds.
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Citations
Cited by
Plant Products as Antimicrobial Agents
Cowan, M. M. (1999) · Clinical Microbiology Reviews · doi:10.1128/cmr.12.4.564 · Cited by 9,043
Recent advances in the chemical composition of propolis
Huang, S., Zhang, C.-P., Wang, K., Li, G., & Hu, F.-L. (2014) · Molecules · doi:10.3390/molecules191219610 · Cited by 765
Propolis and its potential against SARS-CoV-2 infection mechanisms and COVID-19 disease
Berretta, A. A., Silveira, M. A. D., Cóndor Capcha, J. M., & De Jong, D. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110622 · Cited by 269
Chemical composition, oral toxicity and antimicrobial activity of Iranian propolis
Mohammadzadeh, S., Shariatpanahi, M., Hamedi, M., Ahmadkhaniha, R., Samadi, N., & Ostad, S. N. (2007) · Food Chemistry · doi:10.1016/j.foodchem.2006.10.006 · Cited by 158
Comparison of the Biological Potential and Chemical Composition of Brazilian and Mexican Propolis
Silva-Beltrán, N. P., Umsza-Guez, M. A., Ramos Rodrigues, D. M., Gálvez-Ruiz, J. C., de Paula Castro, T. L., & Balderrama-Carmona, A. P. (2021) · Applied Sciences · doi:10.3390/app112311417 · Cited by 30
Metadata
- Authors
- Amoros, M., Simõs, C. M. O., Girre, L., Sauvager, F., & Cormier, M.
- Venue
- Journal of Natural Products
- Publisher
- American Chemical Society (ACS)
- Published
- 1992-12
- Volume
- 55
- Issue
- 12
- Pages
- 1732-1740
- ISSN
- 0163-3864 (ISSN-L)
- 1520-6025
- OpenAlex
- W2051156715
- Cited by
- 299
- References
- 0
- FWCI
- 3.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Synergistic Effect of Flavones and Flavonols Against Herpes Simplex Virus Type 1 in Cell Culture. Comparison with the Antiviral Activity of Propolis. https://app.cochat.ai/papers/10.1021/np50090a003
- The paper
- Amoros, M., Simõs, C. M. O., Girre, L., Sauvager, F., & Cormier, M. (1992). Synergistic Effect of Flavones and Flavonols Against Herpes Simplex Virus Type 1 in Cell Culture. Comparison with the Antiviral Activity of Propolis. Journal of Natural Products. https://doi.org/10.1021/np50090a003
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
