The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Proline-Catalyzed Asymmetric Aldol Reactions between Ketones and α-Unsubstituted Aldehydes
Abstract
[reaction: see text] With this communication we extend the methodology of proline-catalyzed direct asymmetric aldol reactions to include alpha-unsubstituted aldehydes as acceptors. This important aldehyde class gives the corresponding aldols in 22-77% yield and up to 95% ee when the reactions are performed in pure acetone or in ketone/chloroform mixtures. On the basis of these results we have developed a concise new synthesis of (S)-ipsenol.
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Citations
Cites
Catalytic Asymmetric Synthesis of anti-1,2-Diols
Notz, W., & List, B. (2000) · Journal of the American Chemical Society · doi:10.1021/ja001460v · Cited by 645
Self-citation
Cited by
Asymmetric Aminocatalysis—Gold Rush in Organic Chemistry
Melchiorre, P., Marigo, M., Carlone, A., & Bartoli, G. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200705523 · Cited by 1,256
Asymmetric Organocatalysis: From Infancy to Adolescence
Dondoni, A., & Massi, A. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200704684 · Cited by 1,252
Lanthanide Complexes in Multifunctional Asymmetric Catalysis
Shibasaki, M., & Yoshikawa, N. (2002) · Chemical Reviews · doi:10.1021/cr010297z · Cited by 1,199
Proline-catalyzed asymmetric reactions
List, B. (2002) · Tetrahedron · doi:10.1016/s0040-4020(02)00516-1 · Cited by 1,154
Self-citationThe First Direct and Enantioselective Cross-Aldol Reaction of Aldehydes
Northrup, A. B., & MacMillan, D. W. C. (2002) · Journal of the American Chemical Society · doi:10.1021/ja0262378 · Cited by 706
Metadata
- Authors
- List, B., Pojarliev, P., & Castello, C.
- Venue
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2001-01-25
- Volume
- 3
- Issue
- 4
- Pages
- 573-575
- ISSN
- 1523-7052 (ISSN-L)
- 1523-7060
- OpenAlex
- W2071167223
- Cited by
- 381
- References
- 1
- FWCI
- 18.45
- Type
- journal article
- Language
- en
- Open access
- closed
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- List, B., Pojarliev, P., & Castello, C. (2001). Proline-Catalyzed Asymmetric Aldol Reactions between Ketones and α-Unsubstituted Aldehydes. Organic Letters. https://doi.org/10.1021/ol006976y
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