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Cited by 699

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

A Fluorogenic 1,3-Dipolar Cycloaddition Reaction of 3-Azidocoumarins and Acetylenes

Sivakumar, Krishnamoorthy, Xie, Fang, Cash, Brandon M., Long, Su, Barnhill, Hannah N., Wang, Qian·2004·Organic Letters

Abstract

Copper(I)-catalyzed 1,3-dipolar cycloaddition reaction of nonfluorescent 3-azidocoumarins and terminal alkynes afforded intense fluorescent 1,2,3-triazole products. The mild condition of this reaction allowed us to construct a large library of pure fluorescent coumarin dyes. Since both azide and alkyne are quite inert to biological systems, this reaction has potential in bioconjugation and bioimaging applications. [reaction: see text]

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Metadata

Authors
Sivakumar, K., Xie, F., Cash, B. M., Long, S., Barnhill, H. N., & Wang, Q.
Venue
Organic Letters
Published
2004-11-01
Volume
6
Issue
24
Pages
4603-4606
ISSN
  • 1523-7052 (ISSN-L)
  • 1523-7060
OpenAlex
W2164788577
Cited by
699
References
11
FWCI
10.38
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Fluorogenic 1,3-Dipolar Cycloaddition Reaction of 3-Azidocoumarins and Acetylenes. https://app.cochat.ai/papers/10.1021/ol047955x
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Sivakumar, K., Xie, F., Cash, B. M., Long, S., Barnhill, H. N., & Wang, Q. (2004). A Fluorogenic 1,3-Dipolar Cycloaddition Reaction of 3-Azidocoumarins and Acetylenes. Organic Letters. https://doi.org/10.1021/ol047955x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.