The DOI matches its Crossref record.
Copper Sulfate-Pentahydrate-1,10-Phenanthroline Catalyzed Amidations of Alkynyl Bromides. Synthesis of Heteroaromatic Amine Substituted Ynamides
Abstract
A practical cross-coupling of amides with alkynyl bromides using catalytic CuSO(4).5H(2)O and 1,10-phenanthroline is described here. This catalytic protocol is more environmentally friendly than the use of CuCN or copper halides and provides a general entry for syntheses of ynamides including various new sulfonyl and heteroaromatic amine substituted ynamides. Given the interest in ynamides, this N-alkynylation of amides should be significant for the future of ynamides in organic synthesis.
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Citations
Cited by
Ynamides: Versatile Tools in Organic Synthesis
Evano, G., Coste, A., & Jouvin, K. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200905817 · Cited by 812
The Complementary Competitors: Palladium and Copper in C–N Cross-Coupling Reactions
Beletskaya, I. P., & Cheprakov, A. V. (2012) · Organometallics · doi:10.1021/om300683c · Cited by 454
Kanemura, S., Kondoh, A., Yasui, H., Yorimitsu, H., & Oshima, K. (2008) · Bulletin of the Chemical Society of Japan · doi:10.1246/bcsj.81.506 · Cited by 30
Metadata
- Authors
- Zhang, Y., Hsung, R. P., Tracey, M. R., Kurtz, K. C. M., & Vera, E. L.
- Venue
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-03-02
- Volume
- 6
- Issue
- 7
- Pages
- 1151-1154
- ISSN
- 1523-7052 (ISSN-L)
- 1523-7060
- OpenAlex
- W2034664096
- Cited by
- 327
- References
- 0
- FWCI
- 8.26
- Type
- journal article
- Language
- en
- Open access
- closed
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