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KMnO4-Mediated Oxidation as a Continuous Flow Process
Open accessAbstract
An efficient and easily scalable transformation of alcohols and aldehydes to carboxylic acids and nitroalkane derivatives to the corresponding carbonyls and carboxylic acids using permanganate as the oxidant within a continuous flow reactor is reported. Notably, the generation and downstream processing of MnO(2) slurries was not found to cause any blocking of the reactor when ultrasound pulses were applied to the flow system.
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Cited by
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Pastre, J. C., Browne, D. L., & Ley, S. V. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60246j · Cited by 658
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Metadata
- Authors
- Sedelmeier, J., Ley, S. V., Baxendale, I. R., & Baumann, M.
- Venue
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-07-22
- Volume
- 12
- Issue
- 16
- Pages
- 3618-3621
- ISSN
- 1523-7052 (ISSN-L)
- 1523-7060
- OpenAlex
- W2073602542
- Cited by
- 217
- References
- 0
- FWCI
- 9.79
- Type
- journal article
- Language
- en
- Open access
- green
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- Sedelmeier, J., Ley, S. V., Baxendale, I. R., & Baumann, M. (2010). KMnO4-Mediated Oxidation as a Continuous Flow Process. Organic Letters. https://doi.org/10.1021/ol101345z
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