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Assessment of the Metabolism and Intrinsic Reactivity of a Novel Catechol Metabolite
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“The catechols can be further oxidized to reactive ortho-quinones which sequentially alkylate apoprotein of CYPs (Hutzler et al., 2006(Hutzler et al., , 2008)).”
From Piperine Is a Mechanism-Based Inactivator of CYP3A (2020) · cites this paper as Hutzler et al., 2008
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Citations
Cites
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Cited by
Piperine Is a Mechanism-Based Inactivator of CYP3A
Cui, T., Wang, Q., Tian, X., Zhang, K., Peng, Y., & Zheng, J. (2020) · Drug Metabolism and Disposition · doi:10.1124/dmd.119.088955 · Cited by 37
Dual Drug Repurposing: The Example of Saracatinib
Ramos, R., & Vale, N. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25084565 · Cited by 24
Metadata
- Authors
- Hutzler, J. M., Melton, R. J., Rumsey, J. M., Thompson, D. C., Rock, D. A., & Wienkers, L. C.
- Affiliations
- Pharmacokinetics, Dynamics, and Metabolism (PDM), and Drug Safety Research and Development (DSRD), Pfizer Global Research and Development, 700 Chesterfield Parkway West T3A, Chesterfield, Missouri 63017
- Venue
- Chemical Research in Toxicology
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-04-12
- Volume
- 21
- Issue
- 5
- Pages
- 1125-1133
- ISSN
- 0893-228X
- 1520-5010
- Cited by
- 16
- References
- 1
- Language
- en
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.