The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Cytology of Pituitary Thyrotroph Hyperplasia in Protracted Primary Hypothyroidism
Abstract
Pituitary thyrotroph hyperplasia, a rare cause of pituitary enlargement, is usually associated with protracted primary hypothyroidism. We present here a case of pituitary thyrotroph hyperplasia in a 51 year old woman who was thought to have a pituitary macroadenoma with suprasellar extension. The cytologic investigation of the intraoperative touch preparation identified hyperplastic thyrotrophs, provided the correct diagnosis and helped to limit further aggressive surgical removal of the lesion, which is known to regress after adequate thyroid hormone replacement therapy. This is the first study to describe the cytologic features of pituitary thyrotroph hyperplasia confirmed subsequently by histology, immunocytochemistry and transmission electron microscopy.
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Cites
Chatzellis, E., Alexandraki, K., Androulakis, I. I., & Kaltsas, G. (2015) · Neuroendocrinology · doi:10.1159/000371806 · Cited by 576
Thyrotropin-Secreting Pituitary Tumors*
Beck‐Peccoz, P., Brücker-Davis, F., Persani, L., Smallridge, R. C., & Weintraub, B. D. (1996) · Endocrine Reviews · doi:10.1210/edrv-17-6-610 · Cited by 530
Lloyd, R. V., Scheithauer, B. W., Horváth, É., et al. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-396-1_4 · Cited by 299
Functional Endocrine Pathology
McNicol, A. M. (1992) · Histopathology · doi:10.1111/j.1365-2559.1992.tb00931.x · Cited by 130
Horváth, É., Lloyd, R. V., & Kovacs, K. (1990) · PubMed · Cited by 126
Self-citationEndocrine and Morphologic Studies of Pituitary Adenomas Secondary to Primary Hypothyroidism
Samaan, N. A., Osborne, B. M., Mackay, B., et al. (1977) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-45-5-903 · Cited by 112
Pituitary gland in hypothyroidism. Histologic and immunocytologic study.
Scheithauer, B. W., Kovács, K., Randall, R. V., & Ryan, N. (1985) · PubMed · Cited by 104
Fine structural cytology of the adenohypophysis in rat and man
Horváth, É., & Kovács, K. (1988) · Journal of Electron Microscopy Technique · doi:10.1002/jemt.1060080410 · Cited by 101
Pioro, E. P., Scheithauer, B. W., Laws, E. R., Randall, R. V., Kovács, K., & Horváth, É. (1988) · Surgical Neurology · doi:10.1016/0090-3019(88)90010-9 · Cited by 55
Pituitary thyrotroph hyperplasia mimicking prolactin-secreting adenoma
Khalil, A., Kovács, K., Sima, A. A. F., et al. (1984) · Journal of Endocrinological Investigation · doi:10.1007/bf03351025 · Cited by 48
Primary hypothyroidism and pituitary enlargement. Radiological evidence of pituitary regression
Jawadi, M. H. (1978) · Archives of Internal Medicine · doi:10.1001/archinte.138.10.1555 · Cited by 43
Pituitary Hyperplasia Due to Hypothyroidism
Okuno, T., Sudo, M., Momoi, T., et al. (1980) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-198010000-00004 · Cited by 42
Pituitary enlargement mimicking pituitary tumor
Bilaniuk, L. T., Moshang, T., Cara, J. F., et al. (1985) · Journal of neurosurgery · doi:10.3171/jns.1985.63.1.0039 · Cited by 40
Reversible Suprasellar Pituitary Mass Secondary to Hypothyroidism
Atchison, J. A. (1989) · JAMA · doi:10.1001/jama.1989.03430220098038 · Cited by 40
TARGET GLAND INSUFFICIENCY AND PITUITARY TUMOURS
Leiba, S., Landau, B., & Ber, A. (1969) · European Journal of Endocrinology · doi:10.1530/acta.0.0600112 · Cited by 39
MR demonstration of pituitary hyperplasia and regression after therapy for hypothyroidism.
Hutchins, W. W., Crues, J. V., Miya, P., et al. (1990) · PubMed · Cited by 39
Pituitary Gland Enlargement in Primary Hypothyroidism: A Report of 5 Cases with Follow-Up Data
Ahmed, M., Banna, M., Sakati, N., & Woodhouse, N. (2008) · Hormone Research · doi:10.1159/000181287 · Cited by 34
Silver, B. J. (1981) · JAMA · doi:10.1001/jama.1981.03320040036027 · Cited by 31
Primary amenorrhea and pseudoprolactinoma in a patient with primary hypothyroidism
Poretsky, L., Garber, J. R., & Kleefield, J. (1986) · The American Journal of Medicine · doi:10.1016/0002-9343(86)90207-x · Cited by 27
Chan, A. W., MacFarlane, I. A., Foy, P. M., et al. (1990) · British Journal of Neurosurgery · doi:10.3109/02688699008992708 · Cited by 27
Long-Standing Goiter and Hypothyroidism: An Unusual Presentation of a TSH-Secreting Adenoma
Langlois, M., Lamarche, J. B., & Bellabarba, D. (1996) · Thyroid · doi:10.1089/thy.1996.6.329 · Cited by 26
Boyce, R. W., & Beadles, C. F. (1892) · The Journal of Pathology and Bacteriology · doi:10.1002/path.1700010209 · Cited by 25
Groff, T. R., Shulkin, B. L., Utiger, R. D., et al. (1984) · PubMed · Cited by 25
Pituitary hyperplasia secondary to thyroid failure: CT appearance.
Floyd, J. L., Dorwart, R. H., Nelson, M. J., et al. (1984) · PubMed · Cited by 24
Heyburn, P. J., Gibby, O. M., Hourihan, M. D., et al. (1986) · BMJ · doi:10.1136/bmj.292.6536.1660 · Cited by 18
Flagged first, then by citations
Research works printed but not linked: 1
- Horvath E, Scheithauer BW, Kovacs K, Lloyd RV, Regional neuropathology: Hypothalamus and pituitary. In: Graham DI, Lantos PL, eds. Greenfield' Neuropathology. London: Arnold, 6th Edition, 1997;1007–1094.
Cited by
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Roux, A., Rosso, D., Cuboni, D., Maccario, M., Grottoli, S., Arvat, E., & Gasco, V. (2024) · Biomedicines · doi:10.3390/biomedicines12061368 · Cited by 9
“Histological examination revealed pituitary hyperplasia in five cases [6,9,13,44,63], while it allowed for the identification of pure (two cases) or multi-hormonal TSH-secreting adenoma (four cases) in the remaining six cases [22,25,39,43,51].”
Background
Metadata
- Authors
- Alkhani, A. M., Cusimano, M., Kovacs, K., Bilbao, J. M., Horvath, E., & Singer, W.
- Affiliations
- St. Michael's Hospital (CA)
- Venue
- Pituitary
- Published
- 1999-05
- Volume
- 1
- Issue
- 3-4
- Pages
- 291-295
- ISSN
- 1386-341X (ISSN-L)
- 1573-7403
- OpenAlex
- W57803721
- Cited by
- 38
- References
- 25
- Citations by year
- 2024: 2 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2013: 1 · 2012: 3
- FWCI
- 0.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Pituitary (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Keywords
- pituitary enlargement, pituitary macroadenoma, cytological diagnosis, thyrotrophs, thyroid hormone replacement, immunocytochemistry, transmission electron microscopy
- MeSH terms
- Adenoma, Diagnostic Errors, Female, Humans, Hyperplasia, Hypothyroidism, Immunohistochemistry, Microscopy, Electron, Middle Aged, Pituitary Gland, Pituitary Neoplasms, Thyrotropin
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