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Effect of filler type on the mechanical properties of self-reinforced polylactide–calcium phosphate composites
Abstract
Bioabsorbable polymers are of interest as internal fracture fixation devices. Self-reinforcement has been developed to improve the mechanical properties of the material and the addition of calcium phosphate fillers improves the bioactivity. Composite plates, produced by compression molding preimpregnated sheets of polylactide fibers coated in a polylactide matrix have been degraded in simulated body fluid for up to 12 weeks. Some samples also contained hydroxyapatite or tricalcium phosphate filler particles. Degradation was measured by monitoring the water uptake and mass decrease of the samples, as well as carrying out four point bend tests to assess the mechanical properties of the material. By 12 weeks, it was found that the unfilled samples absorbed more water and showed greater mass loss than the samples containing calcium phosphate fillers. Also, the flexural modulus and yield stress decreased significantly at week 12 for the unfilled samples. Adding hydroxyapatite (HA) or tricalcium phosphate (TCP) to the composite increased the flexural modulus and yield strength to values within the range of those reported for cortical bone and these values were maintained over the 12-week period.
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Metadata
- Authors
- Bleach, N. C., Tanner, K. E., Kellomäki, M., & Törmälä, P.
- Affiliations
- University of London (GB)
- Tampere University of Technology (FI)
- Venue
- Journal of Materials Science: Materials in Medicine
- Published
- 2001-12
- Volume
- 12
- Issue
- 10-12
- Pages
- 911-915
- ISSN
- 0957-4530 (ISSN-L)
- 1573-4838
- OpenAlex
- W16097078
- Cited by
- 62
- References
- 13
- Citations by year
- 2024: 2 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 8 · 2015: 3 · 2013: 2 · 2012: 5
- FWCI
- 1.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Journal of Materials Science Materials in Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone fractures and treatments
- Keywords
- hydroxyapatite, tricalcium phosphate, bioresorbable polymers, fracture fixation, bone plates, simulated body fluid degradation, water absorption, flexural modulus, yield strength, bioactivity (biomaterials)
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