The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Lipid synthesis under hydrothermal conditions by Fischer-Tropsch-type reactions
Abstract
Ever since their discovery in the late 1970's, mid-ocean-ridge hydrothermal systems have received a great deal of attention as a possible site for the origin of life on Earth (and environments analogous to mid-ocean-ridge hydrothermal systems are postulated to have been sites where life could have originated or Mars and elsewhere as well). Because no modern-day terrestrial hydrothermal systems are free from the influence of organic compounds derived from biologic processes, laboratory experiments provide the best opportunity for confirmation of the potential for organic synthesis in hydrothermal systems. Here we report on the formation of lipid compounds during Fischer-Tropsch-type synthesis from aqueous solutions of formic acid or oxalic acid. Optimum synthesis occurs in stainless steel vessels by heating at 175 degrees C for 2-3 days and produces lipid compounds ranging from C2 to > C35 which consist of n-alkanols, n-alkanoic acids, n-alkenes, n-alkanes and alkanones. The precursor carbon sources used are either formic acid or oxalic acid, which disproportionate to H2, CO2 and probably CO. Both carbon sources yield the same lipid classes with essentially the same ranges of compounds. The synthesis reactions were confirmed by using 13C labeled precursor acids.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It seems unlikely that such an iron-catalyzed reaction could occur in the prebiotic conditions, but McCollom et al. [59] and Rushdi and Simoneit [60] have shown that a series of carboxylic acids and alcohols are synthesized when formic or oxalic acid solutions are heated under pressure and temperature regimes characteristic of hydrothermal conditions associated with volcanism.”
From The Role of Lipid Membranes in Life’s Origin (2017) · cites this paper as [59]
In the citing paper
“Remarkably, when the temperature exceeded 150 °C the oxalic acid decomposed into carbon monoxide and water which then polymerized into hydrocarbon derivatives ranging from 12 to 33 carbons in length.”
From The Role of Lipid Membranes in Life’s Origin (2017) · cites this paper as [59]
In the citing paper
“Amphiphiles are also synthesized by photochemical reactions (Dworkin et al., 2001) and are products of Fischer- Tropsch type reactions that may occur in volcanic geochemistry (McCollom et al., 1999; Rushdi and Simoneit, 2006).”
From The Hot Spring Hypothesis for an Origin of Life (2020) · cites this paper as McCollom et al., 1999
In the citing paper
“The availability of amphiphiles with sufficiently long hydrophobic tails is amply substantiated [168–171] as is that of hydrophobic and amphiphilic peptides [44,172].”
From Systems protobiology: origin of life in lipid catalytic networks (2018) · cites this paper as [169]
In the citing paper
“There is, in fact, good experimental evidence that long-chain fatty acids can be synthesized under plausible prebiotic conditions”
From Natural pH Gradients in Hydrothermal Alkali Vents Were Unlikely to Have Played a Role in the Origin of Life (2016) · cites this paper as McCollom et al. 1999
In the citing paper
“Long-chain carboxylic acids can be synthesized in Fisher-Tropsch-type syntheses, producing aliphatic chains and carbonyl groups in the inorganic gas condensations catalyzed on the mineral beds (McCollom et al., 1999).”
From The Astrobiology Primer v2.0 (2016) · cites this paper as McCollom et al., 1999
In the citing paper
“Furthermore, simple lipids, such as fatty acids, are found in prebiotic syntheses as well as in meteorite samples [163–168].”
From The RNA world as a model system to study the origin of life (2015) · cites this paper as [167]
Citations
Cites
Petroleum Formation and Occurrence
Tissot, B. P., & Welte, D. H. (1978) · Springer eBooks · doi:10.1007/978-3-642-96446-6 · Cited by 6,480
Petroleum Formation and Occurrence
Tissot, B. P., & Welte, D. H. (1984) · Springer eBooks · doi:10.1007/978-3-642-87813-8 · Cited by 4,013
Petroleum Geochemistry and Geology
Hunt, J. M. (1995) · Medical Entomology and Zoology · Cited by 2,593
Distribution of n-paraffins as a clue to recognition of source beds
Bray, E. E., & Evans, E. D. (1961) · Geochimica et Cosmochimica Acta · doi:10.1016/0016-7037(61)90069-2 · Cited by 1,954
Mechanism of the Fischer-Tropsch reaction. The chain propagation step
Brady, R. C., & Pettit, R. (1981) · Journal of the American Chemical Society · doi:10.1021/ja00395a081 · Cited by 402
Origins of methane in hydrothermal systems
Welhan, J. A. (1988) · Chemical Geology · doi:10.1016/0009-2541(88)90114-3 · Cited by 374
Methane-hydrogen gas seeps, Zambales Ophiolite, Philippines: Deep or shallow origin?
Abrajano, T. A., Sturchio, N. C., Böhlke, J. K., Lyon, G. L., Poreda, R. J., & Stevens, C. M. (1988) · Chemical Geology · doi:10.1016/0009-2541(88)90116-7 · Cited by 348
Submarine hot springs and the origin of life
Miller, S. L., & Bada, J. L. (1988) · Nature · doi:10.1038/334609a0 · Cited by 338
Geochemical constraints on the origin of organic compounds in hydrothermal systems
Shock, E. L. (1990) · Origins of life and evolution of the biosphere · doi:10.1007/bf01808115 · Cited by 299
Masters, C. (1979) · Advances in organometallic chemistry · doi:10.1016/s0065-3055(08)60321-4 · Cited by 287
Flagged first, then by citations
Research works printed but not linked: 4
- Berndt, M. E. and Seyfried, W. E., Jr.: 1997, Effect of olivine alteration and dissolution kinetics on the redox state of carbon and sulfur in the oceanic crust. AGU 1997 Fall Meeting, EOS 78(46), F773.
- Fischer, F.: 1935, Die Synthese der Treibstoffe (Kogasin) und Schmieröle aus Kohlenoxyd und Wasserstoff bei gewöhnlichem Druck. Brennstoff-Chemie 16, 1–11.
- Koch, H. and Gilfert, W.: 1955, Part of the work of H. Koch in: Carbonsäure Synthese aus Olefinen, Kohlenoxyd und Wasser, Brennstoff-Chemie 36, 321–352.
- Palmer, D. A., Weselowski, D. J. and Bell, J. L. S.: 1993, EMF measurements of oxalic and formic acid decomposition kinetics and interaction of acetate with aluminum (III) to high temperatures. EOS 74(16), 327–328.
Cited by
Sorted by citations
Items 301–400 of 484
Mixed fatty acid-phospholipid protocell networks
Põldsalu, I., Köksal, E. S., & Gözen, İ. (2021) · Physical Chemistry Chemical Physics · doi:10.1039/d1cp03832j · Cited by 12
Gaylor, M. O., Miró, P., Vlaisavljevich, B., Kondage, A. A. S., Barge, L. M., Omran, A. P., Videau, P., Swenson, V. A., Leinen, L. J., Fitch, N. W., et al. (2021) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-021-09613-4 · Cited by 12
Molecular Semiotics toward the Emergence of Life
Matsuno, K. (2008) · Biosemiotics · doi:10.1007/s12304-008-9002-8 · Cited by 12
Aqueous alteration in icy planetesimals: The effect of outward transport of gaseous hydrogen
Shibuya, T., Sekine, Y., Kikuchi, S., Kurokawa, H., Fukushi, K., Nakamura, T., & Watanabe, S. (2024) · Geochimica et Cosmochimica Acta · doi:10.1016/j.gca.2024.03.022 · Cited by 11
Enceladus: Astrobiology Revisited
Dávila, A. F., & Eigenbrode, J. L. (2024) · Journal of Geophysical Research Biogeosciences · doi:10.1029/2023jg007677 · Cited by 13
Sokol, A. G., Томиленко, А. А., Бульбак, Т. А., Kruk, A. N., Zaikin, P. A., Sokol, I. A., Seryotkin, Y. V., & Palyanov, Y. N. (2018) · Contributions to Mineralogy and Petrology · doi:10.1007/s00410-018-1472-3 · Cited by 11
Freshwater and Evaporite Brine Compositions on Hadean Earth: Priming the Origins of Life
Sahai, N., Adebayo, S., & Schoonen, M. A. A. (2022) · Astrobiology · doi:10.1089/ast.2020.2396 · Cited by 11
Silica botryoids from chemically oscillating reactions and as Precambrian environmental proxies
Varkouhi, S., & Papineau, D. (2023) · Geology · doi:10.1130/g50948.1 · Cited by 11
Müller, U. F., & Tor, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201400847 · Cited by 11
Pleyer, H. L., Moeller, R., Fujimori, A., Fox, S., & Strasdeit, H. (2022) · Astrobiology · doi:10.1089/ast.2021.0144 · Cited by 11
Question 5: On the Chemical Reality of the RNA World
Lucrezia, D. D., Anella, F., & Chiarabelli, C. (2007) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-007-9098-x · Cited by 11
Toward Accommodating Biosemiotics with Experimental Sciences
Matsuno, K. (2012) · Biosemiotics · doi:10.1007/s12304-012-9156-2 · Cited by 11
Self-assembled prebiotic amphiphile-mixture exhibits tunable catalytic properties
Mandal, R., Ghosh, A., Rout, N. K., Prasad, M., Hazra, B., Sar, S., Das, S. K., Datta, A., & Tarafdar, P. K. (2023) · Organic & Biomolecular Chemistry · doi:10.1039/d3ob00606a · Cited by 10
Geisberger, T., Diederich, P., Kaiser, C. J. O., Vogele, K., Ruf, A., Seitz, C., Simmel, F. C., Eisenreich, W., Schmitt‐Kopplin, P., & Huber, C. (2023) · Scientific Reports · doi:10.1038/s41598-023-42552-w · Cited by 10
Making biological theory more down to Earth
Matsuno, K. (2013) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2013.03.004 · Cited by 10
Primordial sex facilitates the emergence of evolution
Sinai, S., Olejarz, J. W., Neagu, I. A., & Nowak, M. A. (2018) · Journal of The Royal Society Interface · doi:10.1098/rsif.2018.0003 · Cited by 10
An Experimental Protocol for Studying Mineral Effects on Organic Hydrothermal Transformations
Yang, Z., & Fu, X. (2018) · Journal of Visualized Experiments · doi:10.3791/58230 · Cited by 10
Mißbach, H., Steininger, H., Thiel, V., & Goetz, W. (2019) · Astrobiology · doi:10.1089/ast.2018.1997 · Cited by 10
Understanding Life: A Bioinformatics Perspective
Szóstak, N., Wąsik, S., & Błażewicz, J. (2016) · European Review · doi:10.1017/s1062798716000570 · Cited by 10
Hydrothermal Stability of Adenine Under Controlled Fugacities of N2, CO2 and H2
Franiatte, M., Richard, L., Élie, M., Nguyen-Trung, C., Perfetti, E., & LaRowe, D. E. (2008) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-008-9126-5 · Cited by 10
A fundamental limit to the search for the oldest fossils
McMahon, S., & Jordan, S. F. (2022) · Nature Ecology & Evolution · doi:10.1038/s41559-022-01777-0 · Cited by 10
Petroleum Generation, Extraction and Migration and Abiogenic Synthesis in Hydrothermal Systems
Simoneit, B. R. T. (2003) · Springer eBooks · doi:10.1007/978-94-017-0111-2_1 · Cited by 9
Self-citationAliphatic Aldehydes in the Earth’s Crust—Remains of Prebiotic Chemistry?
Großmann, Y., Schreiber, U. K., Mayer, C., & Schmitz, O. J. (2022) · Life · doi:10.3390/life12070925 · Cited by 9
Double Emulsion Droplets as a Plausible Step to Fatty Acid Protocells
Douliez, J. (2023) · Small Methods · doi:10.1002/smtd.202300530 · Cited by 8
Pavlov, A. A., Freissinet, C., GLAVIN, D. P., House, C. H., Stern, J. C., McAdam, A. C., Roussel, A., Dworkin, J. P., Chou, L., Steele, A., et al. (2026) · Astrobiology · doi:10.1177/15311074261417879 · Cited by 8
Deciphering the Origin of Abiotic Organic Compounds on Earth: Review and Future Prospects
Wang, C., Tao, R., Walters, J. B., Tianshi, R. E. N., Nan, J., & Zhang, L. (2023) · Acta Geologica Sinica - English Edition · doi:10.1111/1755-6724.15045 · Cited by 8
Sampling methane in hydrothermal minerals on Earth and Mars
McMahon, S., Parnell, J., & Blamey, N. J. F. (2012) · International Journal of Astrobiology · doi:10.1017/s1473550412000067 · Cited by 8
NMR analysis of nucleotide π-stacking in prebiotically relevant crowded environment
Bapat, N. V., Paithankar, H., Chugh, J., & Rajamani, S. (2020) · Communications Chemistry · doi:10.1038/s42004-020-0300-7 · Cited by 8
Alkanes as Membrane Regulators of the Response of Early Membranes to Extreme Temperatures
Misuraca, L., Caliò, A., LoRicco, J. G., Hoffmann, I., Winter, R., Demé, B., Peters, J., & Oger, P. (2022) · Life · doi:10.3390/life12030445 · Cited by 8
Effects of Bioliquid Recirculation on Hydrothermal Carbonization of Lignocellulosic Biomass
Lee, S., Oh, M., Oh, S., Cho, N.-H., Kang, Y.-Y., & Lee, J.-Y. (2022) · Energies · doi:10.3390/en15134903 · Cited by 8
Akbari, A., & Palsson, B. Ø. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1010377 · Cited by 8
Dubnick, A. J., Faber, Q., Hawkings, J. R., Bramall, N. E., Christner, B. C., Doran, P. T., Nadeau, J., Snyder, C., Kellerman, A. M., Mckenna, A. M., et al. (2022) · Journal of Geophysical Research Biogeosciences · doi:10.1029/2022jg006852 · Cited by 8
Joshi, M. P., Steller, L. H., Kranendonk, M. J. V., & Rajamani, S. (2021) · Life · doi:10.3390/life11121413 · Cited by 8
Self-Reproduction of Micelles, Reverse Micelles, and Vesicles
Stano, P., & Luisi, P. L. (2008) · Elsevier eBooks · doi:10.1016/s1554-4516(08)00009-4 · Cited by 8
Kurihara, H., Yabuta, H., Kaneko, T., Obayashi, Y., Takano, Y., & Kobayashi, K. (2012) · Chemistry Letters · doi:10.1246/cl.2012.441 · Cited by 8
Molecular diversity as a biosignature
Yoffe, G., Klenner, F., Sober, B., Kaspi, Y., & Halevy, I. (2026) · Nature Astronomy · doi:10.1038/s41550-026-02864-z · Cited by 7
Buckner, D. K., Anderson, M. J., Wisnosky, S., Alvarado, W., Nuevo, M., Williams, A. J., Ricco, A. J., Anamika, A., Debic, S., Friend, L., et al. (2023) · Astrobiology · doi:10.1089/ast.2023.0012 · Cited by 7
Prebiotic Peptide Synthesis: How Did Longest Peptide Appear?
Yang, Y., Wang, Z., Bai, J., & Qiao, H. (2025) · Journal of Molecular Evolution · doi:10.1007/s00239-025-10237-9 · Cited by 7
Lewan, M. D. (2017) · Techniques in Dentistry and Oral & Maxillofacial Surgery · doi:10.1007/978-3-319-02330-4_5-1 · Cited by 7
Nanoscale Anatomy of Iron‐Silica Self‐Organized Membranes: Implications for Prebiotic Chemistry
Kotopoulou, E., López‐Haro, M., Calvino, J. J., & García-Ruiz, J. M. (2020) · Angewandte Chemie · doi:10.1002/ange.202012059 · Cited by 7
Chapter 8: Searching for Life Beyond Earth
Chou, L., Grefenstette, N. M., Borges, S. R., Caro, T. A., Catalano, E., Harman, C. E., McKaig, J. M., Raj, C. G., Trubl, G., & Young, A. V. (2024) · Astrobiology · doi:10.1089/ast.2021.0104 · Cited by 7
Decomposition pathways of formamide in the presence of vanadium and titanium monoxides
Nguyen, H. T., & Nguyen, M. T. (2015) · Physical Chemistry Chemical Physics · doi:10.1039/c5cp01456e · Cited by 7
Gao, M., Du, N., Wang, Y., Yuan, S., Liu, L., Liu, J., & Hou, W. (2021) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2021.126374 · Cited by 7
Deamer, D. W. (2007) · Planets and Life · doi:10.1017/cbo9780511812958.011 · Cited by 7
Prebiotic Cell Membranes that Survive Extreme Environmental Pressure Conditions
Kapoor, S., Berghaus, M., Suladze, S., Prumbaum, D., Grobelny, S., Degen, P., Raunser, S., & Winter, R. (2014) · Angewandte Chemie · doi:10.1002/ange.201404254 · Cited by 7
Adamala, K. P., & Luisi, P. L. (2011) · Results and problems in cell differentiation · doi:10.1007/978-3-642-19065-0_1 · Cited by 7
Toward Evolution in Chemical Reaction Networks
Ameta, S., Blokhuis, A. W. P., Jeancolas, C., & Nghe, P. (2022) · Royal Society of Chemistry eBooks · doi:10.1039/9781839164798-00379 · Cited by 8
An experimental approach to production of peptide-like compounds in the early terrestrial planets
Marcano, V., Benítez, P., & Palacios‐Prü, E. (2001) · Planetary and Space Science · doi:10.1016/s0032-0633(00)00172-0 · Cited by 7
Kitadai, N., Shibuya, T., Ueda, H., Tasumi, E., Okada, S., & Takai, K. (2024) · Communications Earth & Environment · doi:10.1038/s43247-024-01689-w · Cited by 6
Kinsler, G., Sinai, S., Lee, N. K., & Nowak, M. A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180208 · Cited by 6
Riggi, V. S., Watson, E. B., Steele, A., & Rogers, K. L. (2023) · Life · doi:10.3390/life13091899 · Cited by 6
Neveu, M. F., Aspin, A., Naseem, M., & Yang, Z. (2024) · Earth and Planetary Science Letters · doi:10.1016/j.epsl.2024.118622 · Cited by 6
Sert, M. F., Niemann, H., Reeves, E. P., Granskog, M. A., Hand, K. P., Kekäläinen, T., Jänis, J., Rossel, P. E., Ferré, B., Silyakova, A., et al. (2022) · Biogeosciences · doi:10.5194/bg-19-2101-2022 · Cited by 6
Bapat, N. V., & Rajamani, S. (2023) · Life · doi:10.3390/life13030766 · Cited by 6
On the Construction of Minimal Cell Models in Synthetic Biology and Origins of Life Studies
Stano, P., & Luisi, P. L. (2011) · Springer eBooks · doi:10.1007/978-1-4419-6766-4_16 · Cited by 6
Stability of Amino Acids and Related Compounds in Simulated Submarine Hydrothermal Systems
Kurihara, H., Takano, Y., Kaneko, T., Obayashi, Y., & Kobayashi, K. (2012) · Bulletin of the Chemical Society of Japan · doi:10.1246/bcsj.20110349 · Cited by 6
Theoretical and Computational Approaches to the Study of the Origin of Life
Segrè, D., & Lancet, D. (2004) · Cellular Origin, Life in Extreme Habitats and Astrobiology · doi:10.1007/1-4020-2522-x_7 · Cited by 6
Methane Carbon Cycling in the Past: Insights from Hydrocarbon and Lipid Biomarkers
Thiel, V. (2020) · Springer eBooks · doi:10.1007/978-3-319-90569-3_6 · Cited by 6
Freire, M. Á. (2015) · Theory in Biosciences · doi:10.1007/s12064-015-0209-3 · Cited by 6
Vance, S. D. (2007) · ResearchWorks at the University of Washington (University of Washington) · Cited by 6
Hazra, B., Prasad, M., Das, S. K., Mandal, R., Sardar, A., Dewangan, N., & Tarafdar, P. K. (2023) · Langmuir · doi:10.1021/acs.langmuir.3c01617 · Cited by 5
Fifer, L. M., & Wong, M. L. (2024) · Astrobiology · doi:10.1089/ast.2023.0109 · Cited by 5
Prebiotic Evolution: The Self-Assembly of Primordial Biomolecules
Sillerud, L. O. (2024) · Springer eBooks · doi:10.1007/978-3-031-56687-5_12 · Cited by 5
Were early Archean carbonate factories major carbon sinks on the juvenile Earth?
Xiang, W., Duda, J., Pack, A., van Zuilen, M. A., & Reitner, J. (2024) · Biogeosciences · doi:10.5194/bg-21-5653-2024 · Cited by 5
Evidence of Heritability in Prebiotically Realistic Membrane-Bound Systems
Sokolskyi, T., Ganju, P., Montgomery-Taylor, R., & Baum, D. (2024) · Life · doi:10.3390/life14030284 · Cited by 5
Fast bilayer-micelle fusion mediated by hydrophobic dipeptides
Wei, C., & Pohorille, A. (2021) · Biophysical Journal · doi:10.1016/j.bpj.2021.04.012 · Cited by 6
Raee, E., Sun, X., Yang, Y., Xu, X., Zhou, Y., Sahai, N., & Liu, T. (2022) · Giant · doi:10.1016/j.giant.2022.100125 · Cited by 5
Chan, Q. H. S., Nomura, H., Kebukawa, Y., Sakon, I., & Taniguchi, K. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99762-1.00145-5 · Cited by 4
Spark of Life: Role of Electrotrophy in the Emergence of Life
Pillot, G., Santiago, Ó., Kerzenmacher, S., & Liebgott, P.-P. (2023) · Life · doi:10.3390/life13020356 · Cited by 4
The Nature of the Spark Is a Pivotal Element in the Design of a Miller–Urey Experiment
Ravanbodshirazi, S., Boutfol, T., Safaridehkohneh, N., Finkler, M., Mohammadi-Kambs, M., & Ott, A. (2023) · Life · doi:10.3390/life13112201 · Cited by 4
Spectroscopic and spectrometric differentiation between abiotic and biogenic material on icy worlds
Hand, K. P., McKay, C. P., & Pilcher, C. B. (2010) · Proceedings of the International Astronomical Union · doi:10.1017/s1743921310007374 · Cited by 4
Myth and fact in the origins of cellular life on Earth
Jowett, P., Rayne, R. C., & Tomàs, S. (2017) · Bioscience Horizons The International Journal of Student Research · doi:10.1093/biohorizons/hzx017 · Cited by 4
A Miller–Urey broth mirrors the mass density distribution of all Beilstein indexed organic molecules
Wollrab, E., & Ott, A. (2018) · New Journal of Physics · doi:10.1088/1367-2630/aae2d4 · Cited by 4
Methane Carbon Cycling in the Past: Insights from Hydrocarbon and Lipid Biomarkers
Thiel, V. (2018) · Springer eBooks · doi:10.1007/978-3-319-54529-5_6-1 · Cited by 4
Introduction—First Billion Years: Habitability
Valentín, E. G. R., Filiberto, J. R., Lynch, K. L., Mamajanov, I., Lyons, T. W., Schulte, M. D., & Méndez, A. (2021) · Astrobiology · doi:10.1089/ast.2020.2314 · Cited by 4
Mullen, L. B., & Sutherland, J. D. (2007) · Angewandte Chemie · doi:10.1002/ange.200700394 · Cited by 4
Zhao, Z., Xinran, L. I. U., Lu, H., & Peng, P. (2022) · Acta Geologica Sinica - English Edition · doi:10.1111/1755-6724.14977 · Cited by 4
Taneja, J., & Higgs, P. G. (2025) · Life · doi:10.3390/life15050724 · Cited by 3
Membrane-Spanning Molecular Lengths as an Agnostic Biosignature
Malaska, M. J., Sandström, H., Hofmann, A. E., Hodyss, R., Rensmo, L., van der Meulen, M., Rahm, M., Cable, M. L., & Lunine, J. I. (2025) · Astrobiology · doi:10.1089/ast.2024.0125 · Cited by 3
Chemical Routes to Primitive Membranes: Prebiotic Lipid Formation at the Origin of Life
Shvetsova, A., & Fiore, M. (2026) · Life · doi:10.3390/life16030497 · Cited by 3
Are We the First: Was There Life Before Our Solar System?
Laine, P., & Jheeta, S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811940-2.00014-9 · Cited by 3
Abiogenic gas: Should the carbon isotope order be reversed?
Wei, Z., Zou, Y., Cai, Y., Tao, W., Wang, L., Guo, J., & Peng, P. (2012) · Journal of Petroleum Science and Engineering · doi:10.1016/j.petrol.2012.01.019 · Cited by 3
Abiotic Synthesis and Role of Amphiphiles in the Encapsulation Process in Life’s Origin
Lopez, A., Chieffo, C., & Fiore, M. (2021) · Advances in astrobiology and biogeophysics · doi:10.1007/978-3-030-81039-9_6 · Cited by 4
Incorporation and localisation of alkanes in a protomembrane model by neutron diffraction
Misuraca, L., LoRicco, J. G., Oger, P., Peters, J., & Demé, B. (2023) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2023.184119 · Cited by 3
Hazra, B., Mandal, R., Sahu, J., Das, S. K., Prasad, M., & Tarafdar, P. K. (2024) · Chemistry - A European Journal · doi:10.1002/chem.202303555 · Cited by 3
How hard is it to encapsulate life? The general constraints on encapsulation
Kempes, C. P., Avila, D., & Mathis, C. (2025) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2024.0297 · Cited by 3
Bai, X., Liu, Z., Ye, K., Wang, Y., Zhang, X., Yue, H., Tian, G., & Feng, S. (2013) · Tetrahedron Letters · doi:10.1016/j.tetlet.2013.11.005 · Cited by 3
Coenzyme und ihre Rolle in der Evolution des Lebens
Kirschning, A. (2020) · Angewandte Chemie · doi:10.1002/ange.201914786 · Cited by 3
Ditzler, M. A., Popović, M., & Zajkowski, T. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824162-2.00010-5 · Cited by 3
Sert, M. F., Niemann, H., Reeves, E. P., Granskog, M. A., Hand, K. P., Kekäläinen, T., Jänis, J., Rossel, P. E., Ferré, B., Silyakova, A., et al. (2022) · doi:10.5194/bg-2021-350 · Cited by 3
Environmental constraints on the origin of life based on membrane formation: the role of salinity
Ginter, T., Dujardin, A., Roumans, S., Rothschild, L. J., & Rheinstadter, M. C. (2024) · International Journal of Astrobiology · doi:10.1017/s147355042400020x · Cited by 3
Characterizing Mixed Single‐Chain Amphiphile‐Based Coacervates as a Robust Protocell System
Patki, G. M., Sridhar, V., & Rajamani, S. (2025) · ChemBioChem · doi:10.1002/cbic.202500437 · Cited by 2
Finkel, P. D. L., Carrizo, D., Parro, V., Vignale, F. A., Farı́as, M. E., & Sánchez‐García, L. (2025) · Astrobiology · doi:10.1177/15311074251366268 · Cited by 2
Teece, B. L., Cannelli, S. M. C., Garibello, C. F., McGlynn, S. E., & Barge, L. M. (2025) · Earth-Science Reviews · doi:10.1016/j.earscirev.2025.105311 · Cited by 2
Chen, F., Zhao, Y., & Ying, J. (2026) · Fundamental Research · doi:10.1016/j.fmre.2026.01.017 · Cited by 2
Bandyopadhyay, U., Das, S., Mulewar, S. S., Tejashwini, R., & Rajamani, S. (2026) · Astrobiology · doi:10.1177/15311074261434675 · Cited by 2
Progress and persistent questions in understanding the origin of life on Earth
Ansari, A. H. (2026) · Discover Life · doi:10.1007/s11084-026-09753-5 · Cited by 2
Shiny metal catalysts at the origin of metabolism
Martin, W. F., Hoffmann, N. K., & Schlikker, M. L. (2026) · Trends in Microbiology · doi:10.1016/j.tim.2026.07.012 · Cited by 3
Dávila, M. J., & Mayer, C. (2023) · Life · doi:10.3390/life13081735 · Cited by 2
Stable parallel looped systems: a new theoretical framework for the evolution of order
Ravuri, M. (2011) · Evolving Systems · doi:10.1007/s12530-011-9044-z · Cited by 2
Metadata
- Authors
- McCollom, T. M., Ritter, G., & Simoneit, B. R. T.
- Affiliations
- Oregon State University (US)
- ORCID
- McCollom, Thomas M.
- Venue
- Origins of life and evolution of the biosphere
- Published
- 1999-03
- Volume
- 29
- Issue
- 2
- Pages
- 153-166
- ISSN
- 0169-6149 (ISSN-L)
- 1573-0875
- OpenAlex
- W1631795182
- Cited by
- 475
- References
- 53
- Citations by year
- 2026: 22 · 2025: 16 · 2024: 26 · 2023: 27 · 2022: 36 · 2021: 29 · 2020: 21 · 2019: 16 · 2018: 23 · 2017: 19 · 2016: 13 · 2015: 21 · 2014: 14 · 2013: 15 · 2012: 18
- FWCI
- 7.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Origins of Life and Evolution of Biospheres (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Aeronautics and Space Administration
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Physical Sciences › Chemical Engineering › Catalysis › Catalysts for Methane Reforming
- Physical Sciences › Earth and Planetary Sciences › Paleontology › Paleontology and Stratigraphy of Fossils
- Keywords
- lipogenesis, hydrothermal systems, origin of life, formic acid, oxalic acid, n-alkanoic acids, n-alkanols, n-alkanes, n-alkenes, alkanones, 13C labeling, stainless steel vessel
- MeSH terms
- Origin of Life, Formates, Hot Temperature, Lipids, Gas Chromatography-Mass Spectrometry, Oceans and Seas, Oxalic Acid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
