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Cancer-related fatigue: Inevitable, unimportant and untreatable? Results of a multi-centre patient survey
Open accessAbstract
Objectives To investigate cancer patients' experience of fatigue and their perceptions about the causes, management and impact of this symptom.Design Cross-sectional, questionnaire-based survey.Settings Three regional cancer centres; Glasgow, Birmingham and Southampton.Participants One thousand three hundred seven outpatients with cancer attending the three units over a 30-day period.Main outcome measures Investigator designed questionnaire and the fatigue sub-scale of the Functional Assessment of Cancer Therapy Fatigue (FACT-F) questionnaire.Results The response rate was 576 of 1307 (44%). Fatigue was reported to affect 58% of patients 'somewhat or very much'. The comparable figures for pain and nausea/vomiting were 22% and 18%, respectively. Fatigue had never been reported to the hospital doctor by 52% (281 of 538) of patients with this symptom. Only 75 patients (14%) had received treatment or advice about the management of their fatigue. Fatigue was reported to be not well-managed by 33% (180 of 538) of patients with this symptom. The comparable figures for pain and nausea/vomiting were 9% (46 of 538) and 7% (37 of 538), respectively. The median FACT-F score was 18 (range 0-52). On multivariate analysis 54% of the variation in FACT-F scores could be explained by the combination of quality of life, depression, dyspnoea, weight loss/anorexia and use of analgesics in the previous month.Conclusions Fatigue has been identified as an important problem by patients with cancer. It affects more patients for more of the time than any other symptom and is regarded by patients as being more important than either pain or nausea/vomiting. Research into the aetiology and management of this symptom should be regarded as a priority.
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In the citing paper
“Patients with lung cancer experience the highest level of CRF.5”
From Effects of Acceptance and Commitment Therapy on fatigue interference and health-related quality of life among patients with advanced lung cancer: A pilot randomized controlled trial (2022) · cites this paper as [5]
Experimental — accuracy not yet measuredIn the citing paper
“Cancer-related fatigue (CRF) is a common problem in cancer patients. Approximately, 80% to 100% of cancer patients report suffering from CRF [4].”
From Effects of Supervised Multimodal Exercise Interventions on Cancer-Related Fatigue: Systematic Review and Meta-Analysis of Randomized Controlled Trials (2015) · cites this paper as [4]
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“Furthermore, it has been shown that patients continue to experience fatigue symptoms for months or years after successful treatment [4].”
From Effects of Supervised Multimodal Exercise Interventions on Cancer-Related Fatigue: Systematic Review and Meta-Analysis of Randomized Controlled Trials (2015) · cites this paper as [4]
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Cites
Krupp, L. B. (1989) · Archives of Neurology · doi:10.1001/archneur.1989.00520460115022 · Cited by 6,172
Yellen, S. B., Cella, D. F., Webster, K., Blendowski, C., & Kaplan, E. (1997) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(96)00274-6 · Cited by 1,964
(1997) · PubMed · Cited by 762
Mock, V., Dow, K. H., Meares, C. J., Grimm, P. M., Dienemann, J. A., Haisfield‐Wolfe, M. E., Quitasol, W., Mitchell, S., Chakravarthy, A. B., & Gage, I. (1997) · PubMed · Cited by 597
Smets, E. M. A., Garssen, B., Cull, A., & de Haes, J. (1996) · British Journal of Cancer · doi:10.1038/bjc.1996.42 · Cited by 456
Randomised controlled trial of graded exercise in patients with the chronic fatigue syndrome
Fulcher, K. Y., & White, P. D. (1997) · BMJ · doi:10.1136/bmj.314.7095.1647 · Cited by 431
Tired, weak, or in need of rest: fatigue among general practice attenders.
David, A. S., Pelosi, A. J., McDonald, E. A., Stephens, D., Ledger, D., Rathbone, R., & MANN, A. H. (1990) · BMJ · doi:10.1136/bmj.301.6762.1199 · Cited by 375
Fatigue in patients with cancer
Stone, P. C., Richards, M., & Hardy, J. R. (1998) · European Journal of Cancer · doi:10.1016/s0959-8049(98)00167-1 · Cited by 268
Correlates of fatigue in people with breast or lung cancer.
Blesch, K. S., Paice, J. A., Wickham, R., Harte, N., Schnoor, D. K., Purl, S., Rehwalt, M., Kopp, P., Manson, S., & Coveny, S. B. (1991) · PubMed · Cited by 248
A study of fatigue in systemic lupus erythematosus.
Krupp, L., LaRocca, N. G., Muir, J., & Steinberg, A. D. (1990) · PubMed · Cited by 209
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Borneman, T. R. (2016) · Oxford University Press eBooks · doi:10.1093/med/9780190204747.003.0029
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Guo, J., Qin, Y., Li, C., He, J., Zeng, L., & Peng, J. (2025) · Cancer Nursing · doi:10.1097/ncc.0000000000001482
Brooks, C. K., & Laura, R. (2025) · British Journal of Occupational Therapy · doi:10.1177/03080226251377928
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Metadata
- Authors
- Stone, P., Richardson, A., Ream, E., Smith, A. G., Kerr, D. J., & Kearney, N.
- Affiliations
- King's College London (GB)
- Royal South Hants Hospital (GB)
- University of Birmingham (GB)
- University of Glasgow (GB)
- Venue
- Annals of Oncology
- Publisher
- Elsevier BV
- Published
- 2000-08
- Volume
- 11
- Issue
- 8
- Pages
- 971-976
- ISSN
- 0923-7534 (ISSN-L)
- OpenAlex
- W2267597394
- Cited by
- 438
- References
- 16
- Citations by year
- 2026: 2 · 2025: 15 · 2024: 9 · 2023: 12 · 2022: 12 · 2021: 13 · 2020: 16 · 2019: 7 · 2018: 13 · 2017: 16 · 2016: 25 · 2015: 24 · 2014: 22 · 2013: 27 · 2012: 13
- FWCI
- 5.78
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Annals of Oncology (publishedVersion)
- PubMed (publishedVersion)
- Open Research (University of Surrey) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Surrey Research Insight Open Access (The University of Surrey) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- University Hospitals Birmingham NHS Foundation Trust
- University of Birmingham
- Cilag
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- cancer-related fatigue, patient experience, fatigue management, symptom management, quality of life, depression, dyspnea, weight loss, analgesic use, cancer outpatients, symptom burden
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Fatigue, Female, Health Surveys, Humans, Male, Middle Aged, Nausea, Neoplasms, Pain, Quality of Life, Vomiting, Weight Loss, Incidence
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