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Measurement of fatigue in cancer patients: Further validation of the Fatigue Symptom Inventory
Abstract
Fatigue is one of the most common and debilitating symptoms experienced by cancer patients, yet until recent years it has received little systematic attention, due in part to the lack of adequate instruments to measure fatigue. The primary aim of this report is to further validate a recently developed measure of fatigue for use with cancer patients: the Fatigue Symptom Inventory (FSI). This 13-item self-report measure was designed to measure the intensity and duration of fatigue and its interference with quality of life. The FSI was originally validated in a sample of breast cancer patients and a sample of healthy individuals. In this study, the FSI was evaluated in an outpatient sample that included male and female cancer patients, as well as some older patients, with a variety of cancer diagnoses. A seven-item interference scale was found to have good internal consistency, with alpha coefficients above 0.90. Convergent validity was demonstrated via comparisons with an existing measure of fatigue. Construct validity was demonstrated via comparisons with measure of life satisfaction and depression as well as comparisons among subgroups of patients expected to differ in their experience of fatigue. Overall, the FSI was further established as a valid and reliable measure of fatigue in cancer patients. The potential application of this measure in psychosocial oncology research is discussed.
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“The FSI is a 13-item fatigue self-report measure with evidence of reliability and validity in cancer populations [21, 54].”
From Comparative responsiveness and minimally important difference of fatigue symptom inventory (FSI) scales and the FSI-3 in trials with cancer survivors (2022) · cites this paper as [54]
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Metadata
- Authors
- Hann, D. M., Denniston, M. M., & Baker, F.
- Affiliations
- American Cancer Society (US)
- Venue
- Quality of Life Research
- Published
- 2000-07
- Volume
- 9
- Issue
- 7
- Pages
- 847-854
- ISSN
- 0962-9343 (ISSN-L)
- 1573-2649
- OpenAlex
- W1548686894
- Cited by
- 258
- References
- 20
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 11 · 2023: 15 · 2022: 12 · 2021: 17 · 2020: 14 · 2019: 10 · 2018: 14 · 2017: 9 · 2016: 21 · 2015: 8 · 2014: 8 · 2013: 11 · 2012: 8
- FWCI
- 0.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Quality of Life Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Keywords
- cancer-related fatigue, fatigue measurement, psychometric validation, construct validity, convergent validity, internal consistency, quality of life, depression, life satisfaction, psycho-oncology
- MeSH terms
- Adult, Aged, Aged, 80 and over, Fatigue, Female, Humans, Male, Middle Aged, Neoplasms, Psychiatric Status Rating Scales, Psychometrics, Quality of Life, Surveys and Questionnaires, Reproducibility of Results
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