Prenatal Viral Infection Leads to Pyramidal Cell Atrophy and Macrocephaly in Adulthood: Implications for Genesis of Autism and Schizophrenia

A simple method of estimating 50 per cent end points

Muench, H. (1938) · Medical Entomology and Zoology · Cited by 8,376

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression∗∗See accompanying Editorial, in this issue.

Rajkowska, G., Miguel-Hidalgo, J. J., Wei, J., Dilley, G., Pittman, S. D., Meltzer, H. Y., Overholser, J. C., Roth, B. L., & Stockmeier, C. A. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00041-4 · Cited by 1,477

Decrease in Reelin and Glutamic Acid Decarboxylase67 (GAD67) Expression in Schizophrenia and Bipolar Disorder

Guidotti, A., Auta, J., Davis, J. M., Gerevini, V. D. G., Dwivedi, Y., Grayson, D. R., Impagnatiello, F., Pandey, G. N., Pesold, C., Sharma, R. P., et al. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.11.1061 · Cited by 1,222

Adult Schizophrenia Following Prenatal Exposure to an Influenza Epidemic

Mednick, S. A. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800260109013 · Cited by 1,203

Neuronal and Glial Somal Size in the Prefrontal Cortex: A Postmortem Morphometric Study of Schizophrenia and Huntington Disease

Rajkowska, G., Selemon, L. D., & Goldman-Rakic, P. S. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.3.215 · Cited by 537

Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression

Fatemi, S. H., Earle, J. A., & McMenomy, T. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000783 · Cited by 447

Startle Habituation and Sensorimotor Gating in Schizophrenia and Related Animal Models

Geyer, M. A., & BRAFF, D. L. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.4.643 · Cited by 411

Follow-up report on autism in congenital rubella

Chess, S. (1977) · Journal of Autism and Childhood Schizophrenia · doi:10.1007/bf01531116 · Cited by 378

Defective corticogenesis and reduction in Reelin immunoreactivity in cortex and hippocampus of prenatally infected neonatal mice

Fatemi, S. H., Emamian, E. S., Kist, D. A., Sidwell, R. W., Nakajima, K., Akhter, P., Shier, A. C., Sheikh, S. A., & Bailey, K. W. (1999) · Molecular Psychiatry · doi:10.1038/sj.mp.4000520 · Cited by 266

Serum autoantibodies to brain in Landau-Kleffner variant, autism, and other neurologic disorders

Connolly, A. M., Chez, M. G., Pestronk, A., Arnold, S. T., Mehta, S., & Deuel, R. K. (1999) · The Journal of Pediatrics · doi:10.1016/s0022-3476(99)70248-9 · Cited by 236

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Fatemi, S. H. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001248 · Cited by 79

Prenatal immune challenge in rats: Effects of polyinosinic–polycytidylic acid on spatial learning, prepulse inhibition, conditioned fear, and responses to MK-801 and amphetamine

Vorhees, C. V., Graham, D. L., Braun, A. A., Schaefer, T. L., Skelton, M. R., Richtand, N. M., & Williams, M. T. (2014) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2014.10.007 · Cited by 80

Reduced ventricular proliferation in the foetal cortex following maternal inflammation in the mouse

Stolp, H. B., Turnquist, C., Dzięgielewska, K. M., Saunders, N. R., Anthony, D. C., & Molnár, Z. (2011) · Brain · doi:10.1093/brain/awr237 · Cited by 74

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Fatemi, S. H., Reutiman, T. J., Folsom, T. D., & Sidwell, R. W. (2008) · The Cerebellum · doi:10.1007/s12311-008-0017-0 · Cited by 68

Early Life Exposure to the 1918 Influenza Pandemic and Old-Age Mortality by Cause of Death

Myrskylä, M., Mehta, N. K., & Chang, V. W. (2013) · American Journal of Public Health · doi:10.2105/ajph.2012.301060 · Cited by 71

Evidence for differential alternative splicing in blood of young boys with autism spectrum disorders

Stamova, B. S., Tian, Y., Nordahl, C. W., Shen, M. D., Rogers, S. J., Amaral, D. G., & Sharp, F. R. (2013) · Molecular Autism · doi:10.1186/2040-2392-4-30 · Cited by 70

Obstetrical complications and subsequent schizophrenia in adolescent and young adult offsprings: is there a relationship?

Boog, G. (2004) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2003.09.041 · Cited by 65

Resilience priming: Translational models for understanding resiliency and adaptation to early life adversity

Kentner, A. C., Cryan, J. F., & Brummelte, S. (2019) · Developmental Psychobiology · doi:10.1002/dev.21775 · Cited by 64

Maternal and fetal inflammatory responses in unexplained fetal death

Blackwell, S. C., Romero, R. J., Chaiworapongsa, T., Kim, Y. M., Bujold, E., Espinoza, J., Camacho, N., Hassan, S. S., Yoon, B. H., & Refuerzo, J. (2003) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/713606613 · Cited by 64

Prenatal Infection and Autism Spectrum Disorders in Childhood: A Population‐Based Case–Control Study in T aiwan

Fang, S., Wang, S. Z., Huang, N., Yeh, H.-H. H., & Chen, C. (2015) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.12194 · Cited by 64

Prenatal immune challenge in rats: altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route-based learning as a function of maternal body weight gain after prenatal exposure to poly IC

Vorhees, C. V., Graham, D. L., Braun, A. A., Schaefer, T. L., Skelton, M. R., Richtand, N. M., & Williams, M. T. (2012) · Synapse · doi:10.1002/syn.21561 · Cited by 62

Epigenetic signaling in schizophrenia

Ibi, D., & González‐Maeso, J. (2015) · Cellular Signalling · doi:10.1016/j.cellsig.2015.06.003 · Cited by 62

Combination of prenatal immune challenge and restraint stress affects prepulse inhibition and dopaminergic/GABAergic markers

Deslauriers, J., Larouche, A., Sarret, P., & Grignon, S. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.05.006 · Cited by 63

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Fatemi, S. H. (2005) · International review of neurobiology · doi:10.1016/s0074-7742(05)71008-4 · Cited by 60

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Otero, A. M., & Antonson, A. M. (2022) · Immunological Reviews · doi:10.1111/imr.13125 · Cited by 57

Manganese-enhanced magnetic resonance imaging reveals increased DOI-induced brain activity in a mouse model of schizophrenia

Malkova, N. V., Gallagher, J. J., Yu, C. Z., Jacobs, R. E., & Patterson, P. H. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1323287111 · Cited by 56

Effect of camel milk on thymus and activation-regulated chemokine in autistic children: double-blind study

Bashir, S., & AL-Ayadhi, L. Y. (2013) · Pediatric Research · doi:10.1038/pr.2013.248 · Cited by 57

Individual differences in maternal response to immune challenge predict offspring behavior: Contribution of environmental factors

Bronson, S. L., Ahlbrand, R., Horn, P. S., Kern, J. R., & Richtand, N. M. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.12.040 · Cited by 58

Sex effects on neurodevelopmental outcomes of innate immune activation during prenatal and neonatal life

Rana, S. A., Aavani, T., & Pittman, Q. J. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.03.015 · Cited by 57

Autism: Neuropathology, Alterations of the GABAergic System, and Animal Models

van Kooten, I. A. J., Hof, P. R., van Engeland, H., Steinbusch, H. W. M., Patterson, P. H., & Schmitz, C. (2005) · International review of neurobiology · doi:10.1016/s0074-7742(05)71001-1 · Cited by 54

Animal Models of Maternal Immune Activation in Depression Research

Ronovsky, M., Berger, S., Molz, B., Berger, A., & Pollak, D. D. (2015) · Current Neuropharmacology · doi:10.2174/1570159x14666151215095359 · Cited by 49

Perinatal inflammation: a common factor in the early origins of cardiovascular disease?

Nguyen, M. U., Wallace, M. J., Pepe, S., Menheniott, T. R., Moss, T. J. M., & Burgner, D. P. (2015) · Clinical Science · doi:10.1042/cs20150045 · Cited by 49

Maternal effects in mammals: Broadening our understanding of offspring programming

Edwards, P. D., Lavergne, S. G., McCaw, L. K., Wijenayake, S., Boonstra, R., McGowan, P. O., & Holmes, M. M. (2021) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2021.100924 · Cited by 49

IL-4 Shapes Microglia-Dependent Pruning of the Cerebellum During Postnatal Development

Guedes, J. R., Ferreira, P. A., Costa, J., Laranjo, M., Pinto, M. J., Reis, T., Cardoso, A. M., Lebre, C., Casquinha, M., Gomes, M. A., et al. (2022) · Neuron · doi:10.1016/j.neuron.2023.09.031 · Cited by 47

Airborne inflammatory factors from the nose to the brain

Tonelli, L. H. (2009) · Frontiers in Bioscience-Scholar · doi:10.2741/s52 · Cited by 47

Maternal Immune Activation Produces Cerebellar Hyperplasia and Alterations in Motor and Social Behaviors in Male and Female Mice

Aavani, T., Rana, S. A., Hawkes, R. B., & Pittman, Q. J. (2015) · The Cerebellum · doi:10.1007/s12311-015-0669-5 · Cited by 50

Prenatal viral infection of mice at E16 causes changes in gene expression in hippocampi of the offspring

Fatemi, S. H., Folsom, T. D., Reutiman, T. J., Huang, H., Oishi, K., & Mori, S. (2009) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2009.03.004 · Cited by 45

Increased RNA editing in maternal immune activation model of neurodevelopmental disease

Tsivion-Visbord, H., Kopel, E., Feiglin, A., Sofer, T., Barzilay, R., Ben‐Zur, T., Yaron, O., Offen, D., & Levanon, E. Y. (2020) · Nature Communications · doi:10.1038/s41467-020-19048-6 · Cited by 43

Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats

Watanabe, Y., Hashimoto, S., Kakita, A., Takahashi, H., Ko, J., Mizuno, M., Someya, T., Patterson, P. H., & Nawa, H. (2004) · Neuroscience Research · doi:10.1016/j.neures.2003.12.001 · Cited by 43

Respiratory Viral Infection in Neonatal Piglets Causes Marked Microglia Activation in the Hippocampus and Deficits in Spatial Learning

Elmore, M. R. P., Burton, M. D., Conrad, M. S., Rytych, J. L., Alstine, W. G. V., & Johnson, R. W. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.2180-13.2014 · Cited by 41

Exposure to intrauterine inflammation alters metabolomic profiles in the amniotic fluid, fetal and neonatal brain in the mouse

Brown, A. G., Tulina, N. M., Barila, G., Hester, M. S., & Elovitz, M. A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0186656 · Cited by 41

Glial fibrillary acidic protein and glutamic acid decarboxylase 65 and 67 kDa proteins are increased in brains of neonatal BALB/c mice following viral infection in utero

Fatemi, S. H. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(03)00175-0 · Cited by 40

Transgenerational epigenetic impacts of parental infection on offspring health and disease susceptibility

Kleeman, E. A., Gubert, C., & Hannan, A. J. (2022) · Trends in Genetics · doi:10.1016/j.tig.2022.03.006 · Cited by 41

Innate immune responses to pathogens at the maternal–fetal interface

Alippe, Y., Hatterschide, J., Coyne, C. B., & Diamond, M. (2025) · Nature reviews. Immunology · doi:10.1038/s41577-025-01191-0 · Cited by 41

A direct cross-talk between interferon-γ and sonic hedgehog signaling that leads to the proliferation of neuronal precursor cells

Sun, L., Tian, Z., & Wang, J. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.09.016 · Cited by 38

Multigenerational Effects of Early-Life Health Shocks

Cook, C. J., Fletcher, J. M., & Forgues, A. L. (2019) · Demography · doi:10.1007/s13524-019-00804-3 · Cited by 43

Associating schizophrenia, long non-coding RNAs and neurostructural dynamics

Merelo, V., Durand, D., Lescallette, A. R., Vrana, K. E., Hong, L. E., Faghihi, M. A., & Bellon, A. (2015) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2015.00057 · Cited by 38

Viral regulation of aquaporin 4, connexin 43, microcephalin and nucleolin

Fatemi, S. H., Folsom, T. D., Reutiman, T. J., & Sidwell, R. W. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.09.031 · Cited by 37

Peptide Sharing Between Influenza A H1N1 Hemagglutinin and Human Axon Guidance Proteins

Lucchese, G., Capone, G., & Kanduc, D. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs197 · Cited by 37

Acute sleep deprivation during pregnancy in rats: Rapid elevation of placental and fetal inflammation and kynurenic acid

Baratta, A. M., Kanyuch, N., Cole, C. A., Valafar, H., Deslauriers, J., & Pocivavsek, A. (2019) · Neurobiology of Stress · doi:10.1016/j.ynstr.2019.100204 · Cited by 38

The Power and promise of Identifying Autism Early: Insights from the Search for Clinical and Biological Markers

Pierce, K., Glatt, S. J., Liptak, G. S., & McIntyre, L. L. (2009) · Annals of Clinical Psychiatry · doi:10.1177/104012370902100302 · Cited by 37

Behavioral and Molecular Biomarkers in Translational Animal Models for Neuropsychiatric Disorders

Sarnyai, Z., Alsaif, M., Bahn, S., Ernst, A., Guest, P. C., Hradetzky, E., Kluge, W. F., Stelzhammer, V., & Wesseling, H. (2011) · International review of neurobiology · doi:10.1016/b978-0-12-387718-5.00008-0 · Cited by 35

Prostaglandin E2 and misoprostol induce neurite retraction in Neuro-2a cells

Tamiji, J., & Crawford, D. A. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.06.098 · Cited by 33

Paternal immune activation by Poly I:C modulates sperm noncoding RNA profiles and causes transgenerational changes in offspring behavior

Kleeman, E. A., Reisinger, S. N., Adithya, P., Houston, B. J., Stathatos, G. G., Garnham, A. L., McLaughlin, S., O’Bryan, M. K., Gubert, C., & Hannan, A. J. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.10.005 · Cited by 34

RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation

Saffari, A., Arno, M. J., Nasser, E. E., Ronald, A., Wong, C. C. Y., Schalkwyk, L. C., Mill, J. S., Dudbridge, F., & Meaburn, E. L. (2019) · Molecular Autism · doi:10.1186/s13229-019-0285-1 · Cited by 32

Moderately pathogenic maternal influenza A virus infection disrupts placental integrity but spares the fetal brain

Antonson, A. M., Kenney, A. D., Chen, H. J., Corps, K. N., Yount, J. S., & Gur, T. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.05.004 · Cited by 33

Viral infections in pregnancy and impact on offspring neurodevelopment: mechanisms and lessons learned

Yates, E. F., & Mulkey, S. B. (2024) · Pediatric Research · doi:10.1038/s41390-024-03145-z · Cited by 35

Effects of Two Commonly Found Strains of Influenza A Virus on Developing Dopaminergic Neurons, in Relation to the Pathophysiology of Schizophrenia

Landreau, F., Galeano, P., Caltana, L. R., Masciotra, L., Chertcoff, A. V., Pontoriero, A., Baumeister, E. G., Amoroso, M., Brusco, H. A., Tous, M. I., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051068 · Cited by 34

CXCR4 signaling regulates radial glial morphology and cell fate during embryonic spinal cord development

Mithal, D. S., Ren, D., & Miller, R. J. (2013) · Glia · doi:10.1002/glia.22515 · Cited by 31

Maternal Immune Activation and Autism in Offspring: What Is the Evidence for Causation?

Gardner, R. M., Brynge, M., Sjöqvist, H., Dalman, C., & Karlsson, H. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.11.009 · Cited by 34

Maternal immune-related conditions during pregnancy may be a risk factor for neuropsychiatric problems in offspring throughout childhood and adolescence

Patel, S., Cooper, M. N., Jones, H. F., Whitehouse, A., Dale, R. C., & Guastella, A. J. (2020) · Psychological Medicine · doi:10.1017/s0033291720001580 · Cited by 32

Month of Conception and Learning Disabilities: A Record-Linkage Study of 801,592 Children

Mackay, D., Smith, G. C. S., Cooper, S., Wood, R., King, A., Clark, D. N., & Pell, J. P. (2016) · American Journal of Epidemiology · doi:10.1093/aje/kww096 · Cited by 28

Brain Structural and Functional Alterations in Mice Prenatally Exposed to LPS Are Only Partially Rescued by Anti-Inflammatory Treatment

Aria, F., Bonini, S. A., Cattaneo, V., Premoli, M., Mastinu, A., Maccarinelli, G., & Memo, M. (2020) · Brain Sciences · doi:10.3390/brainsci10090620 · Cited by 28

Astrocytes as Pharmacological Targets in the Treatment of Schizophrenia

Pocivavsek, A., Notarangelo, F. M., Wu, H., Bruno, J. P., & Schwarcz, R. M. (2015) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-800981-9.00025-0 · Cited by 30

Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders

Liu, Q., Chen, M.-X., Sun, L., Wallis, C. U., Zhou, J., Ao, L., Li, Q., & Sham, P. C. (2019) · World Journal of Stem Cells · doi:10.4252/wjsc.v11.i2.55 · Cited by 29

Peripheral Blood Leukocyte Production of BDNF following Mitogen Stimulation in Early Onset and Regressive Autism

Enstrom, A. M., Onore, C. E., Tarver, A., Hertz‐Picciotto, I., Hansen, R. L., Croen, L., de Water, J. V., & Ashwood, P. (2008) · American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology · doi:10.3844/ajbbsp.2008.121.129 · Cited by 28

Register data suggest lower intelligence in men born the year after flu pandemic

Eriksen, W., Sundet, J. M., & Tambs, K. (2009) · Annals of Neurology · doi:10.1002/ana.21702 · Cited by 26

The Timing and Specificity of Prenatal Immune Risk Factors for Autism Modeled in the Mouse and Relevance to Schizophrenia

McAlonan, G. M., Li, Q., & Cheung, C. (2010) · Neurosignals · doi:10.1159/000321080 · Cited by 24

Factoring neurotrophins into a neurite-based pathophysiological model of schizophrenia

Bellon, A., Krebs, M., & Jay, T. M. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.04.003 · Cited by 27

Seropositivity and Serointensity of Toxoplasma gondii Antibodies and DNA among Patients with Schizophrenia

Omar, A., Bakar, O. C., Adam, N. F., Osman, H., Osman, A., Suleiman, A. H., Manaf, M. R. A., & Selamat, M. I. (2015) · Korean Journal of Parasitology · doi:10.3347/kjp.2015.53.1.29 · Cited by 25

The cellular and behavioral consequences of interleukin-1 alpha penetration through the blood–brain barrier of neonatal rats: A critical period for efficacy

Tohmi, M., Tsuda, N., Zheng, Y., Mizuno, M., Sotoyama, H., Shibuya, M., Kawamura, M., Kakita, A., Takahashi, H., & Nawa, H. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.08.034 · Cited by 25

Contribution of Pro-Inflammatory Molecules Induced by Respiratory Virus Infections to Neurological Disorders

Böhmwald, K., Andrade, C. A., & Kalergis, A. M. (2021) · Pharmaceuticals · doi:10.3390/ph14040340 · Cited by 28

Potential teratogenic effects of ultrasound on corticogenesis: Implications for autism

Williams, E. L., & Casanova, M. F. (2010) · Medical Hypotheses · doi:10.1016/j.mehy.2010.01.027 · Cited by 25

Modeling the role of infections in the etiology of mental illness

Pearce, B. D. (2003) · Clinical Neuroscience Research · doi:10.1016/s1566-2772(03)00098-7 · Cited by 21

Association Analysis of Two Single-Nucleotide Polymorphisms of the RELN Gene with Autism in the South African Population

Sharma, J. R., Arieff, Z., Gameeldien, H., Davids, M., Kaur, M., & van der Merwe, L. (2012) · Genetic Testing and Molecular Biomarkers · doi:10.1089/gtmb.2012.0212 · Cited by 25

ORIGINAL ARTICLE: H3N2 Influenza A Virus Replicates in Immortalized Human First Trimester Trophoblast Cell Lines and Induces Their Rapid Apoptosis

Trinh, Q. D., Izumi, Y., Komine‐Aizawa, S., Shibata, T., Shimotai, Y., Kuroda, K., Mizuguchi, M., Ushijima, H., Mor, G., & Hayakawa, S. (2009) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2009.00723.x · Cited by 21

Intrauterine inflammation reduces postnatal neurogenesis in the hippocampal subgranular zone and leads to accumulation of hilar ectopic granule cells

Hester, M. S., Tulina, N. M., Brown, A. G., Barila, G., & Elovitz, M. A. (2018) · Brain Research · doi:10.1016/j.brainres.2018.02.005 · Cited by 21

The effects of prenatal H1N1 infection at E16 on FMRP, glutamate, GABA, and reelin signaling systems in developing murine cerebellum

Fatemi, S. H., Folsom, T. D., Liesch, S. B., Kneeland, R. E., Yousefi, M. K., & THURAS, P. D. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23949 · Cited by 19

Psychotropic viruses

Lipkin, W. I., & Hornig, M. (2004) · Current Opinion in Microbiology · doi:10.1016/j.mib.2004.06.012 · Cited by 19

Nonrespiratory sites of influenza‐associated disease: mechanisms and experimental systems for continued study

Froggatt, H. M., & Heaton, N. S. (2022) · FEBS Journal · doi:10.1111/febs.16363 · Cited by 20

Altered immune function associated with disordered neural connectivity and executive dysfunctions: A neurophysiological study on children with autism spectrum disorders

Han, Y. M. Y., Chan, A. S.-Y., Sze, S. L., Cheung, M., Wong, C. K., Lam, J. M. K., & Poon, P. M. K. (2013) · Research in Autism · doi:10.1016/j.rasd.2013.02.011 · Cited by 18

Maternal Immune Activation, Cytokines and Autism

Patterson, P. H., Xu, W., Smith, S. E. P., & Devarman, B. E. (2008) · Humana Press eBooks · doi:10.1007/978-1-60327-489-0_13 · Cited by 17

Probable transmisión vertical del virus de la influenza A (H1N1): a propósito de un caso

Vásquez, R., Pérez, V. C. A., Gamio, I. E., Muñoz, R. I., Polar, M. F., Montalvo, R., & Ticona, E. (2010) · Revista Peruana de Medicina Experimental y Salud Pública · doi:10.1590/s1726-46342010000300022 · Cited by 16

Autism genes and the leukocyte transcriptome in autistic toddlers relate to pathogen interactomes, infection and the immune system. A role for excess neurotrophic sAPPα and reduced antimicrobial Aβ

Carter, C. (2019) · Neurochemistry International · doi:10.1016/j.neuint.2019.03.007 · Cited by 15

Lymphocyte subset alterations related to executive function deficits and repetitive stereotyped behavior in autism

Han, Y. M. Y., Leung, W. W., Wong, C. K., Lam, J. M. K., Cheung, M., & Chan, A. S.-Y. (2010) · Research in Autism · doi:10.1016/j.rasd.2010.06.013 · Cited by 15

Predicting autism at birth

Steinman, G. (2013) · Medical Hypotheses · doi:10.1016/j.mehy.2013.03.034 · Cited by 14

Maternal Infection and Neurodevelopmental Disorders in the Offspring

Ranwa (2012) · American Journal of Immunology · doi:10.3844/ajisp.2012.10.17 · Cited by 14

Month of birth and risk of autism spectrum disorder: a retrospective cohort of male children born in Israel

Ram, H. S., Solt, I., & Chodick, G. (2017) · BMJ Open · doi:10.1136/bmjopen-2016-014606 · Cited by 14

Clinical Perspectives on Autoimmune Processes in Schizophrenia

Yum, S. Y., Yum, S. K., Kim, T., & Hwang, M. Y. (2009) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2009.09.003 · Cited by 14

Pandémie de grippe A H1N1 2009 et grossesse : épidémiologie, diagnostic et prise en charge

Picone, O., Ami, O., Vauloup‐Fellous, C., Martinez, V., Guillet, M., Dupont-Bernabé, C., Donnadieu, A. C., Trichot, C., Sénat, M., Fernandez, H., et al. (2009) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/j.jgyn.2009.09.016 · Cited by 14

Maternal Influenza and Offspring Neurodevelopment

Egorova, M., Egorov, V. V., & Zabrodskaya, Y. A. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46010023 · Cited by 15

Maternal infection and white matter toxicity

Harry, G. J., Lawler, C. P., & Brunssen, S. (2006) · NeuroToxicology · doi:10.1016/j.neuro.2006.05.004 · Cited by 16

Autism: The Centrality of Active Pathophysiology and the Shift from Static to Chronic Dynamic Encephalopathy

Chauhan, A., Chauhan, V., & Brown, T. (2009) · CRC Press eBooks · doi:10.1201/9781420068870-22 · Cited by 13

Effect of experimental genital mycoplasmosis on gene expression in the fetal brain.

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Olgiati, P., Mandelli, L., Lorenzi, C., Marino, E., Pirovano, A., Ferrari, B., Ronchi, D. D., & Serretti, A. (2009) · Acta Neuropsychiatrica · doi:10.1111/j.1601-5215.2009.00360.x · Cited by 12

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