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Cited by 269Health Systems, Economic Evaluations, Quality of LifeHIV/AIDS Research and InterventionsHealth Education and Validation

The DOI matches its Crossref record; 80 of the 82 references it cites were found in a registry or an index.

Applications of the Medical Outcomes Study health-related quality of life measures in HIV/AIDS

Wu, A. W., Hays, R. D., Kelly, S., Malitz, F., Bozzette, S. A.·1997·Quality of Life Research
DOI 10.1023/a:1018460132567
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Abstract

The leading health status instruments in human immunodeficiency virus (HIV) research are based on the pool of items developed as part of the Medical Outcomes Study (MOS). The measures include the SF-20, MOS-HIV, SF-36, SF-12, SF-56, SF-38 (Patient Reported Status and Experience Survey (PARSE)), SF-21 and HIV Cost and Service Utilization Study (HCSUS) questionnaires. The instrument length ranges from 12 to 56 items, covering two to 11 dimensions. Completion requires from 2 to 14 minutes. Subscales are scored on a 0-100 scale (a higher score indicates better health); physical and mental health or overall summary scores are available for most of the measures. Three of the instruments are available in multiple languages. The instruments have been administered to over 20,000 persons with HIV in descriptive studies and clinical trials and there is substantial evidence for their reliability, construct and predictive validity and responsiveness. In several studies the measures have shown important differences between treatments. Although existing measures do not assess all domains relevant to HIV disease, additional subscales are available from the MOS pool. Some of the subscales may be prone to floor and ceiling effects. However, summary scales that encompass all of the subscales reduce this issue. Selection among MOS measures should be dictated by specific questions, the balance of available time and resources, and practical concerns.

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Citations

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Show all 82 references

Research works printed but not linked: 23

  1. Wu AW, Lichter SL, Richardson W et al. Quality of life in patients receiving clarithromycin for Mycobacterium avium complex infection and AIDS. In: Eighth International Conference on AIDS/III STD World Congress, Amsterdam, 19–24 July 1992.
  2. Scott-Lennox J, McLaughlin Miley CJ, Mauskopf JA. Impact of lamivudine and zidovudine therapy on quality of life (QOL). In: XI International Conference on AIDS, Vancouver, 7–12 July 1996.
  3. Wu AW, Jacobson D, Grant D, Scott-Lennox J. Quality of life scores predict clinical trial attrition and mortality. Abstracts 4th Conf Retroviruses Opportun Infect. 1997; 31: 298.
  4. Revicki DA, Swartz C. Quality of life outcomes of saquinavir, zalcitabine, and combination saquinavirzalcitabine therapy for advanced HIV-infection. Abstracts 4th Conf Retroviruses Opportun Infect. 1997; 27: 266.
  5. Davidson A, Rietmeijer C, Hagglund B, Paulson A, St John M, Cohn D. Relation of social factors to health care utilization and health status assessment in HIV-infected patients. In: Eighth International Conference on AIDS, Amsterdam, July 1992.
  6. Bertram S, Reitmeijer C, Hagglund, Cohn K, St John M, Davidson A: health status measures (HSM) in HIV infected women and men. In: Ninth International Conference on AIDS, Berlin, June 1993.
  7. Zander KJ, Palitzsch M, Kirchberger I et al. HIV-infektion und gesundheitsbezogene Lebensqualität: psychometrische prüfung der deutschsprachigen version de “MOS-HIV”-fragebogens zur therapieerfolgskontrolle. (HIV infection and health related quality of life: psychometric testing of the German version of the MOS-HIV questionnaire.) AIDS-Forschung (AIFO) 1994; 9: 241–249.
  8. Rissi M, Marchesi S, Morelli E, Avogardi M. Quality of life in PWAs, Evaluation by the Medical Outcomes Instrument. AIDS Patient Care 1994; 10: 265–268.
  9. Scott-Lennox JA, Boyer JG, Ware JE, Wu AW. A psychometric validation of French, German, Italian, Dutch, and UK English translations of the MOS-HIV health status questionnaire. In press.
  10. Wu AW, Jacobson D, Clark B, Berzon R, Scott-Lennox J. Reliability, validity and responsiveness of the MOS-HIV HRQL instrument after cultural adaptation in Europe: Results from an international clinical trial. In: Third Annual DIA Symposium on Quality of Life Evaluation, Boston, 9–10 May 1996.
  11. Wu AW, Jacobson D, Clark B, Brookmyer R, Feinberg J. Quality of life associated with valacyclovir vs. high and low dose acyclovir for prophylaxis against cytomegalovirus in AIDS. Abstracts 4th Conf Retroviruses Opportun Infect. 1997; 31: 297.
  12. Doob PR, Johnson KM, St Cyr J, MacFadden DK. Soft and hard measures of energy/fatigue in HIV Trials. In: XI International Conference on AIDS, Vancouver 7–12 July 1996.
  13. Zander K, Jager H, Palitzsch M, Poppinger JV Steinbuchel N, Bullinger M. Health related quality of life (HRQL) in HIV disease: influence of symptom load, functioning, mood and coping styles. In: Ninth International Conference on AIDS, Berlin, June 1993.
  14. Wu AW, Gray S, Brookmeyer R, Safrin S. Quality of life in a double-blind randomized trial of 3 oral regimens for mild-to-moderate pneumocystis carinii pneumonia in AIDS (ACTG 108). In XI International Conference on AIDS. 7–12 July 1996. Vancouver.
  15. Hooker M, Newberry A, Nunn A et al. Changes in quality of life (QOL) indices by treatment group for Delta trial participants beginning HIV therapy. In: XI International Conference on AIDS, Vancouver, 7–12 July 1996.
  16. Wu AW, Rubin HR, Mathews WC, et al. Functional status and well-being in a placebo-controlled trial of zidovudine in early AIDS-related complex. J AIDS 1993; 6: 452–458.
  17. Lamping DL. Measuring quality of life in HIV infection: validation of the SF-36 Short-Form Health Survey. In: IXth International Conference on AIDS. Berlin, June 1993.
  18. Gange SJ, Jacobson LP, Kass N et al. Quality of life among seropositive patients on monotherapy and combination antiretroviral therapy. Qual Life Res, in press.
  19. Lamping DL, Abrahamowicz M, Gilmore N, et al: A randomized, controlled trial to evaluate a psychosocial intervention to improve quality of life in HIV infection. In: Ninth International Conference on AIDS, Berlin, June 1993.
  20. Arpinelli F, Visona G, de Carli G, Paparatti UDL, Recchia G. HIV positivity impact on quality of life in asymptomatic patients. DIA Quality of Life Symposium. Charleston, SC. 12–14 May, 1997.
  21. Berry SH, Bozzette SA, Hays RD, Stewart A, Kanouse DE. Measuring patient reported health status and experience in advanced HIV disease: HIV-PARSE Survey Instrument. Santa Monica, CA. RAND, 1991.
  22. Testa MA, Lenderking WR, Fischer L, Revicki DA, Collier AC. Effects of combination therapy with saquinavir, zidovudine, and zalcitabine on quality of life. In: XI International Conference on AIDS, Vancouver.
  23. Stewart AL, Ware JE, eds. Measuring Functioning and Well-being. The Medical Outcomes Study Approach. Durham, NC: Duke University Press, 1992.

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Metadata

Authors
Wu, A. W., Hays, R. D., Kelly, S., Malitz, F., & Bozzette, S. A.
Affiliations
  • Johns Hopkins University (US)
  • University of California, Los Angeles (US)
  • Social and Scientific Systems (United States) (US)
  • RAND Corporation (US)
ORCID
Venue
Quality of Life Research
Publisher
Springer Science and Business Media LLC
Published
1997-11
Volume
6
Issue
6
Pages
531-554
ISSN
  • 0962-9343 (ISSN-L)
  • 1573-2649
DOI
10.1023/a:1018460132567
OpenAlex
W1597395255
Cited by
269
References
82
Citations by year
2026: 1 · 2025: 2 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 11 · 2020: 4 · 2019: 5 · 2018: 14 · 2017: 6 · 2016: 10 · 2015: 8 · 2014: 2 · 2013: 15 · 2012: 13
FWCI
35.38
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Quality of Life Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Agency for Healthcare Research and Quality (HS07824)
  • National Eye Institute (U10EY008052, U10 EY 0850, U10-EY08052)
Topics
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
  • Health Sciences › Nursing › Research and Theory › Health Education and Validation
Keywords
HIV/AIDS, health-related quality of life, Medical Outcomes Study, SF-36, SF-20, MOS-HIV, Parse, health status questionnaires, instrument selection, floor and ceiling effects
MeSH terms
Female, Health Surveys, Humans, Male, Psychometrics, Quality of Life, Reproducibility of Results, HIV Infections, Outcome Assessment, Health Care

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