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Quality of Life in Persons with Irritable Bowel Syndrome (Development and Validation of a New Measure)
Abstract
How irritable bowel syndrome (IBS) and its treatment affect quality of life (QOL) is important. To develop a quality-of-life measure specific to irritable bowel syndrome, items were generated using a conceptual model and qualitative interviews with persons diagnosed using the Rome criteria. Symptom frequency and bothersomeness indices were created. Psychometric evaluation methods involved an initial cross-sectional survey followed by a repeat survey. The resulting 34-item measure demonstrated high internal consistency (Cronbach's alpha = 0.95) and high reproducibility (ICC = 0.86) with average time of seven days (SD = 1). For discriminant validity: number of symptoms (P < 0.05), self-reported severity of symptoms (P < 0.001), and the functional bowel disorder severity index (P < 0.001) significantly predicted IBS-QOL scores. Convergent validity and analyses confirmed predictions that scores are more closely related to psychological well-being (0.45) than to function (0.36). We conclude this measure meets established psychometric criteria for reliability and validity; testing of its responsiveness is warranted.
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“Changes in physical and psychosocial functioning as a result of IBS were measured with the IBS-Quality of Life (IBS-QOL) scale, a 34-item scale that is responsive to therapeutic change (Drossman et al., 2000), and has high test-retest reliability (Patrick et al., 1998).”
From Therapeutic mechanisms of a mindfulness-based treatment for IBS: effects on visceral sensitivity, catastrophizing, and affective processing of pain sensations. (2012) · cites this paper as Patrick et al., 1998
In the citing paper
“The IBS-QOL shows high internal consistency (Chronbach's α = .95) and test-retest reliability (r = .86) [46].”
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Metadata
- Authors
- Patrick, D. L., Drossman, D. A., Frederick, I. O., Dicesare, J., & Puder, K. L.
- Affiliations
- University of Washington (US)
- Venue
- Digestive Diseases and Sciences
- Published
- 1998-02
- Volume
- 43
- Issue
- 2
- Pages
- 400-411
- ISSN
- 0163-2116 (ISSN-L)
- 1573-2568
- OpenAlex
- W1532990492
- Cited by
- 761
- References
- 26
- Citations by year
- 2026: 41 · 2025: 44 · 2024: 43 · 2023: 41 · 2022: 54 · 2021: 44 · 2020: 33 · 2019: 31 · 2018: 41 · 2017: 24 · 2016: 36 · 2015: 33 · 2014: 37 · 2013: 28 · 2012: 27
- FWCI
- 10.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Digestive Diseases and Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
- Keywords
- irritable bowel syndrome, quality of life, IBS-QOL, psychometric validation, symptom frequency, Rome criteria, psychological well-being, reproducibility
- MeSH terms
- Adult, Colonic Diseases, Functional, Female, Health Status Indicators, Humans, Male, Middle Aged, Psychometrics, Quality of Life, Reproducibility of Results
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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