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Quality of Life in Persons with Irritable Bowel Syndrome (Development and Validation of a New Measure)
Abstract
How irritable bowel syndrome (IBS) and its treatment affect quality of life (QOL) is important. To develop a quality-of-life measure specific to irritable bowel syndrome, items were generated using a conceptual model and qualitative interviews with persons diagnosed using the Rome criteria. Symptom frequency and bothersomeness indices were created. Psychometric evaluation methods involved an initial cross-sectional survey followed by a repeat survey. The resulting 34-item measure demonstrated high internal consistency (Cronbach's alpha = 0.95) and high reproducibility (ICC = 0.86) with average time of seven days (SD = 1). For discriminant validity: number of symptoms (P < 0.05), self-reported severity of symptoms (P < 0.001), and the functional bowel disorder severity index (P < 0.001) significantly predicted IBS-QOL scores. Convergent validity and analyses confirmed predictions that scores are more closely related to psychological well-being (0.45) than to function (0.36). We conclude this measure meets established psychometric criteria for reliability and validity; testing of its responsiveness is warranted.
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“Changes in physical and psychosocial functioning as a result of IBS were measured with the IBS-Quality of Life (IBS-QOL) scale, a 34-item scale that is responsive to therapeutic change (Drossman et al., 2000), and has high test-retest reliability (Patrick et al., 1998).”
From Therapeutic mechanisms of a mindfulness-based treatment for IBS: effects on visceral sensitivity, catastrophizing, and affective processing of pain sensations. (2012) · cites this paper as Patrick et al., 1998
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“The IBS-QOL shows high internal consistency (Chronbach's α = .95) and test-retest reliability (r = .86) [46].”
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Metadata
- Authors
- Patrick, D. L., Drossman, D. A., Frederick, I. O., Dicesare, J., & Puder, K. L.
- Affiliations
- University of Washington (US)
- Venue
- Digestive Diseases and Sciences
- Published
- 1998-02
- Volume
- 43
- Issue
- 2
- Pages
- 400-411
- ISSN
- 0163-2116 (ISSN-L)
- 1573-2568
- OpenAlex
- W1532990492
- Cited by
- 761
- References
- 26
- Citations by year
- 2026: 41 · 2025: 44 · 2024: 43 · 2023: 41 · 2022: 54 · 2021: 44 · 2020: 33 · 2019: 31 · 2018: 41 · 2017: 24 · 2016: 36 · 2015: 33 · 2014: 37 · 2013: 28 · 2012: 27
- FWCI
- 10.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Digestive Diseases and Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
- Keywords
- irritable bowel syndrome, quality of life, IBS-QOL, psychometric validation, symptom frequency, Rome criteria, psychological well-being, reproducibility
- MeSH terms
- Adult, Colonic Diseases, Functional, Female, Health Status Indicators, Humans, Male, Middle Aged, Psychometrics, Quality of Life, Reproducibility of Results
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