Enteral long-term nutrition via percutaneous endoscopic gastrostomy (PEG) in 210 patients a four-year prospective study
Abstract
After PEG placement at the Medical Department of the University Hospital in Kiel, 210 patients (mean age 61.3 years; 137 men, 73 women) were prospectively followed-up for 133+/-181 days. Close-meshed evaluations of the development of nutritional status, long-term outcome, complications, subjective acceptability, patient care after discharge from the hospital, survival, and nutritional long-term problems were performed. The PEG procedure (duration 13.3+/-4.2 min) was carried out for neurological (42%), ear-nose-throat (28%), and internal medical (30%) indications. Procedure-related mortality was 0%, while altogether 3.8% severe and 20.0% mild complications were observed. Body weight decreased by a mean of 11.4+/-1.5 kg in the three months before and increased by 3.5+/-1.7 kg one year after PEG placement with no significant differences between malignant or benign underlying diseases. Individual subjective acceptability was excellent in 83%, sufficient in 15%, and poor in 2% of patients only. One-year survival rate was 34.3%. The various results of the present prospective study demonstrate that long-term enteral feeding via PEG is a safe, effective, easy-to-practice, and highly acceptable method with excellent long-term results and distinct improvement of nutritional status. Individual decisions for PEG placement should be considered much earlier and more frequently in appropriate patients.
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Enteral nutrition is frequently commenced late after substantial weight loss has already developed, which is in the stage of severe malnutrition and hampers effective nutritional therapy.
“EN is frequently commenced late after substantial weight loss has already developed, which is in the stage of severe malnutrition (128, 129) and which hampers effective nutritional therapy (130).”
From ESPEN practical guideline: Clinical nutrition and hydration in geriatrics (2022) · cites this paper as [128]
Some studies show that a substantial weight loss has frequently occurred before the initiation of EN, i.e. on average 11.4 kg in the study by Loser et al.
“Some studies show that a substantial weight loss has frequently occurred before the initiation of EN, i.e. on average 11.4 kg in the study byLoser et al. (128, 136).”
From ESPEN practical guideline: Clinical nutrition and hydration in geriatrics (2022) · cites this paper as [128]
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ESPEN practical guideline: Clinical nutrition and hydration in geriatrics
Volkert, D., Beck, A. M., Cederholm, T., Cruz-Jentoft, A., Hooper, L., Kiesswetter, E., Maggio, M., Raynaud-Simon, A., Sieber, C., Sobotka, L., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.01.024 · Cited by 516 · see citing works
- Authors
- Loser, C., Wolters, S., & Folsch, U. R.
- Venue
- Digestive Diseases and Sciences
- Published
- 1998-11
- Volume
- 43
- Issue
- 11
- Pages
- 2549-2557
- ISSN
- 0163-2116 (ISSN-L)
- 1573-2568
- OpenAlex
- W1471276
- Cited by
- 157
- References
- 0
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 9 · 2017: 4 · 2016: 7 · 2015: 3 · 2014: 10 · 2013: 4 · 2012: 6
- FWCI
- 5.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Digestive Diseases and Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Health Professions › Speech and Hearing › Dysphagia Assessment and Management
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Keywords
- percutaneous endoscopic gastrostomy, long-term enteral nutrition, nutritional status, PEG complications, patient acceptability, survival, weight change, neurological disorders, internal medicine patients
- MeSH terms
- Adult, Aged, Aged, 80 and over, Enteral Nutrition, Female, Follow-Up Studies, Gastroscopy, Gastrostomy, Humans, Male, Middle Aged, Prospective Studies, Time Factors, Body Mass Index, Survival Rate, Treatment Outcome
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