Cited by 575Gastrointestinal motility and disordersPsychosomatic Disorders and Their TreatmentsGastrointestinal Bleeding Diagnosis and Treatment

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Demography, Clinical Characteristics, Psychological and Abuse Profiles, Treatment, and Long-Term Follow-up of Patients with Gastroparesis

Soykan, Irfan, Sivri, Bulent, Sarosiek, Irene, Kiernan, Brian, Mccallum, Richard W.·1998·Digestive Diseases and Sciences

DOI 10.1023/a:1026665728213

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Abstract

Patients with gastroparesis frequently present challenging clinical, diagnostic, and therapeutic problems. Data from 146 gastroparesis patients seen over six years were analyzed. Patients were evaluated at the time of initial diagnosis and at the most recent follow-up in terms of gastric emptying and gastrointestinal symptomatology. The psychological status and physical and sexual abuse history in female idiopathic gastroparesis patients were ascertained and an association between those factors and gastrointestinal symptomatology was sought. Eighty-two percent of patients were females (mean age: 45 years old). The mean age for onset of gastroparesis was 33.7 years. The etiologies in 146 patients are: 36% idiopathic, 29% diabetic, 13% postgastric surgery, 7.5% Parkinson's disease, 4.8% collagen vascular disorders, 4.1% intestinal pseudoobstruction, and 6% miscellaneous causes. Subgroups were identified within the idiopathic group: 12 patients (23%) had a presentation consistent with a viral etiology, 48% had very prominent abdominal pain. Other subgroups were gastroesophageal reflux disease and nonulcer dyspepsia (19%), depression (23%), and onset of symptoms immediately after cholecystectomy (8%). Sixty-two percent of women with idiopathic gastroparesis reported a history of physical or sexual abuse, and physical abuse was significantly associated with abdominal pain, somatization, depression, and lifetime surgeries. At the end of the follow-up period, 74% required continuous…

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Authors: Soykan, I., Sivri, B., Sarosiek, I., Kiernan, B., & Mccallum, R. W.
ORCID: Mccallum, Richard W.
Venue: Digestive Diseases and Sciences
Publisher: Springer Science and Business Media LLC
Published: 1998-11
Volume: 43
Issue: 11
Pages: 2398-2404
ISSN: 0163-2116 (ISSN-L)
1573-2568
DOI: 10.1023/a:1026665728213
OpenAlex: W1502294688
Cited by: 575
References: 23
Citations by year: 2026: 11 · 2025: 18 · 2024: 15 · 2023: 24 · 2022: 24 · 2021: 24 · 2020: 42 · 2019: 36 · 2018: 21 · 2017: 26 · 2016: 26 · 2015: 30 · 2014: 20 · 2013: 31 · 2012: 28
FWCI: 2.44
Type: journal article
Language: en
Open access: closed
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Digestive Diseases and Sciences (publishedVersion)
PubMed (publishedVersion)
Funders: National Center for Research Resources (M01RR000847)
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
Keywords: gastroparesis, idiopathic gastroparesis, gastric emptying, physical abuse, sexual abuse, depression, somatization, abdominal pain, prokinetic therapy, treatment response, long-term outcomes, Parkinson's disease, connective tissue diseases, viral etiology, gastroesophageal reflux disease, functional dyspepsia, cholecystectomy, gastric electrical stimulation
MeSH terms: Adolescent, Adult, Aged, Combined Modality Therapy, Demography, Disease Susceptibility, Female, Follow-Up Studies, Gastric Emptying, Humans, Male, Middle Aged, Psychometrics, Time Factors, Battered Women, Gastroparesis, Statistics, Nonparametric

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Demography, Clinical Characteristics, Psychological and Abuse Profiles, Treatment, and Long-Term Follow-up of Patients with Gastroparesis

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