The prevalence of allergy to egg: A population-based study in young children

Eggesbø, M.; Botten, G.; Halvorsen, R.; Magnus, P.

doi:10.1034/j.1398-9995.2001.056005403.x

Cited by 290Food Allergy and Anaphylaxis ResearchEosinophilic EsophagitisDrug-Induced Adverse Reactions

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The prevalence of allergy to egg: A population-based study in young children

Eggesbø, M., Botten, G., Halvorsen, R., Magnus, P.·2001·Allergy

DOI 10.1034/j.1398-9995.2001.056005403.x

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Abstract

BACKGROUND: The aim of the present study was to estimate the prevalence of adverse reactions to egg, as population-based prevalence estimates based on objective diagnostic procedures are lacking. METHODS: The parents of 2721 children in a population-based birth cohort completed questionnaires on the occurrence of any reaction to food at 12, 18, and 24 months of age. Children with parentally reported reactions to eggs at the age of 2 years were selected for further examination. A stepwise diagnostic procedure was developed that included diet trials at home, skin prick tests, and open and double-blind, placebo-controlled food challenges. The mean age of the children at the time of the examination was 2.5 years (CI 2.5-2.6). A sample of children without perceived reactions to egg was also selected for assessment of unrecognized reactions. RESULTS: The estimated point prevalence of allergy to egg in children aged 2(1/2) years was 1.6% (CI 1.3-2.0%), with an upper estimate of the cumulative incidence by this age calculated roughly at 2.6% (CI 1.6-3.6). Almost all reactions were IgE mediated. In general, two-thirds of the parentally perceived reactions were verified. However, the positive predictive value of a parentally perceived reaction depended on the number of times it had been reported, and increased from 50% to 100%, for reactions reported one and three times, respectively. Unrecognized reactions were infrequent. CONCLUSION: This study confirms that allergy to egg is frequent in a child population.

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Prevalence rates for other common food allergies are 2.0-3.0% for milk allergy, 2.0% for peanuts, 0.8-2.0% for eggs, and 1.0% for tree nuts.
“This compares with prevalence rates of 2.0–3.0% for milk allergy [173,175], 2.0% for peanuts [173], 0.8–2.0% for eggs [176,177], and 1.0% for tree nuts [173,178,179].”
From Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function (2020) · cites this paper as [176]

An Introduction to the Bootstrap
Efron, B., & Tibshirani, R. J. (1993) · doi:10.1007/978-1-4899-4541-9 · Cited by 21,230
Practical Statistics for Medical Research.
Bartko, J. J., & Altman, D. G. (1992) · Journal of the American Statistical Association · doi:10.2307/2290246 · Cited by 4,834
Probable Inference, the Law of Succession, and Statistical Inference
Wilson, E. B. (1927) · Journal of the American Statistical Association · doi:10.1080/01621459.1927.10502953 · Cited by 4,476
Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents
Sampson, H. A., & Ho, D. G. (1997) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(97)70133-7 · Cited by 1,059
Prospective Appraisal of Complaints of Adverse Reactions to Foods in Children During the First 3 Years of Life
Bock, S. A. (1987) · PEDIATRICS · doi:10.1542/peds.79.5.683 · Cited by 740
Double-blind, placebo-controlled food challenge (DBPCFC) as an office procedure: A manual
Bock, S. A., Sampson, H. A., Atkins, F. M., Zeiger, R. S., Lehrer, S. B., Sachs, M. I., Bush, R. K., & Metcafe, D. D. (1988) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(88)90135-2 · Cited by 714
Comparison of results of skin tests, RAST, and double-blind, placebo-controlled food challenges in children with atopic dermatitis
Sampson, H. A., & Albergo, R. P. (1984) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(84)90083-6 · Cited by 590
Patterns of food hypersensitivity during sixteen years of double-blind, placebo-controlled food challenges
Bock, S. A., & Atkins, F. M. (1990) · The Journal of Pediatrics · doi:10.1016/s0022-3476(05)80689-4 · Cited by 461
A Prospective Study of Cow's Milk Allergy in Exclusively Breast‐Fed Infants
Høst, A., Husby, S., & ØSterballe, O. (1988) · Acta Paediatrica · doi:10.1111/j.1651-2227.1988.tb10727.x · Cited by 354
Standardization of Diagnostic Work in Allergy
Aas, K., & Belin, L. (2009) · International Archives of Allergy and Applied Immunology · doi:10.1159/000231002 · Cited by 288
Allergenic activity of heated and ovomucoid-depleted egg white
Urisu, A., Ando, H., Morita, Y., Wada, E., Yasaki, T., Yamada, K., Komadac, K., Torii, S., Gotoe, M., & Wakamatsu, T. (1997) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(97)70220-3 · Cited by 285
Malabsorption syndrome with cow's milk intolerance. Clinical findings and course in 54 cases.
KUITUNEN, P., Visakorpi, J. K., Savilahti, E., & Pelkonen, P. (1975) · Archives of Disease in Childhood · doi:10.1136/adc.50.5.351 · Cited by 285
Outcome of double‐blind, placebo‐controlled food challenge tests in 107 children with atopic dermatitis
Niggemann, Sielaff, Beyer, Binder, & Wahn (1999) · Clinical and Experimental Allergy · doi:10.1046/j.1365-2222.1999.00454.x · Cited by 279
Objective clinical and laboratory studies of immediate hypersensitivity reactions to foods in asthmatic children
May, C. D. (1976) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(76)90194-9 · Cited by 274
Development of childhood allergy in infants fed breast, soy, or cow milk
Halpern, S. R., Sellers, W. A., Johnson, R. B., Anderson, D. S., Saperstein, S., & Reisch, J. (1973) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(73)90019-5 · Cited by 244
Food-dependent, exercise-induced anaphylaxis: A study on 11 Japanese cases
Dohi, M., Suko, M., Sugiyama, H., Yamashita, N., Tadokoro, K., Juji, F., Okudaira, H., Sano, Y., Ito, K., & Miyamoto, T. (1991) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(91)90210-f · Cited by 201
Breastfeeding, maternal smoking and lower respiratory tract infections
Nafstad, P. H. J., Jaakkola, J. J. K., Hagen, J., Botten, G., & Kongerud, J. S. (1996) · European Respiratory Journal · doi:10.1183/09031936.96.09122623 · Cited by 181
Skin test reactivity to histamine from infancy to old age
Skassa-Brociek, W., Manderscheid, J.-C., Michel, F. B., & Bousquet, J. (1987) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(87)90292-2 · Cited by 150
Skin test reactivity in infancy
Ménardo, J.-L., Bousquet, J., Rodière, M., Astruc, J., & Michel, F. B. (1985) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(85)90088-0 · Cited by 148
Prevalence of parentally perceived adverse reactions to food in young children
Eggesbø, M. Å., Halvorsen, R., Tambs, K., & Botten, G. (1999) · Pediatric Allergy and Immunology · doi:10.1034/j.1399-3038.1999.00022.x · Cited by 148
FOOD ALLERGY IN FINNISH CHILDREN AGED 1 TO 6 YEARS
Kajosaari, M. (1982) · Acta Paediatrica · doi:10.1111/j.1651-2227.1982.tb09525.x · Cited by 145
The prevalence of CMA/CMPI in young children: the validity of parentally perceived reactions in a population‐based study
Eggesbø, M. Å., Botten, G., Halvorsen, R., & Magnus, P. M. (2001) · Allergy · doi:10.1034/j.1398-9995.2001.056005393.x · Cited by 122
Clinical spectrum of food allergy in children in Australia and South-East Asia: identification and targets for treatment
Hill, D. J., Hosking, C. S., & Heine, R. G. (1999) · Annals of Medicine · doi:10.3109/07853899908995890 · Cited by 114
Immunologically mediated food allergy: the importance of food challenge procedures.
Sampson, H. A. (1988) · PubMed · Cited by 113
A Modern Clinical Approach to Food Hypersensitivity
May, C. D., & Block, S. A. (1978) · Allergy · doi:10.1111/j.1398-9995.1978.tb01532.x · Cited by 112
Food-processing approaches to altering allergenic potential of milk-based formula
Lee, Y.-H. (1992) · The Journal of Pediatrics · doi:10.1016/s0022-3476(05)81406-4 · Cited by 96
Clinical manifestations of cows’ milk allergy in childhood. II. The diagnostic value of skin tests and RAST
Hill, D. J., DUKE, A. M., Hosking, C. S., & Hudson, I. L. (1988) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1988.tb02898.x · Cited by 90
Distinct patterns of cow's milk allergy in infancy defined by prolonged, two-stage double-blind, placebo-controlled food challenges
Baehler, P., Chad, Z. H., Gurbindo, C., Bonin, A., BOUTHILLIER, L., & Seidman, E. G. (1996) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1996.tb00089.x · Cited by 73
What safety measures need to be taken in oral food challengesin children?
Reibel, S., Röhr, C., Ziegert, M., Sommerfeld, C., Wahn, U., & Niggemann, B. (2000) · Allergy. European Journal of Allergy and Clinical Immunology · doi:10.1034/j.1398-9995.2000.00689.x · Cited by 70
Influence of skin prick test criteria on estimation of prevalence and incidence of allergic sensitization in children
Meinert, R., Frischer, T., Karmaus, W. J. J., & Kuehr, J. (1994) · Allergy · doi:10.1111/j.1398-9995.1994.tb01124.x · Cited by 70
Clinical manifestations of cows’ milk allergy in childhood. I. Associations with in‐vitro cellular immune responses
Hill, D. J., Ball, G., & Hosking, C. S. (1988) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1988.tb02897.x · Cited by 56
Are confusion and controversy about food hypersensitivity really necessary?
May, C. D. (1985) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(85)90067-3 · Cited by 39
Egg and cows' milk allergy in children.
Ford, R. P., & Fergusson, D. M. (1980) · Archives of Disease in Childhood · doi:10.1136/adc.55.8.608 · Cited by 22
The importance of appropriate challenges in diagnosing food sensitivity
Kaplan, M. S. (1994) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1994.tb00234.x · Cited by 12
294 Adverse reactions to foods during the first three years of life
Bock, S. A. (1985) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(85)90429-4 · Cited by 6
Use of the term “false positive” in referring to results of food skin tests
Bock, S. A. (1985) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(85)80029-4 · Cited by 5
Detecting and describing heterogeneity in meta-analysis
Hardy, R. J., & Thompson, S. G. (1998) · Statistics in Medicine · doi:10.1002/(sici)1097-0258(19980430)17:8

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Guidelines for the Diagnosis and Management of Food Allergy in the United States
Boyce, J. A., Assa'ad, A., Burks, A., Jones, S., Sampson, H. A., Wood, R., Plaut, M., Cooper, S. F., Fenton, M. J., Arshad, S., et al. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.10.008 · Cited by 1,690
Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel
Boyce, J. A., Assa’ad, A., Burks, A. W., Jones, S. M., Sampson, H. A., Wood, R. A., Plaut, M., Cooper, S. F., Fenton, M. J., Arshad, S. H., et al. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.10.007 · Cited by 1,263
Prevalence of common food allergies in Europe: a systematic review and meta-analysis
Nwaru, B. I., Hickstein, L., Panesar, S. S., Roberts, G. C., Muraro, A. M., Sheikh, A., & the EAACI Food Allergy and Anaphylaxis Guidelines Group (2014) · Allergy · doi:10.1111/all.12423 · Cited by 891
Epidemiology of food allergy
Sicherer, S. H. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.11.044 · Cited by 723
Oral Immunotherapy for Treatment of Egg Allergy in Children
Burks, A. W., Jones, S. M., Wood, R. A., Fleischer, D. M., Sicherer, S. H., Lindblad, R., Stablein, D. M., Henning, A. K., Vickery, B. P., Liu, A. H., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1200435 · Cited by 699
Standardization of food challenges in patients with immediate reactions to foods – position paper from the European Academy of Allergology and Clinical Immunology
Bindslev‐Jensen, C., Ballmer-Weber, B. K., Bengtsson, U. J., Blanco, C., Ebner, C., Hourihane, J. O., Knulst, A. C., Moneret‐Vautrin, D. A., Nékám, K., Niggemann, B., et al. (2004) · Allergy · doi:10.1111/j.1398-9995.2004.00466.x · Cited by 682
“Proposed starting dose for different foods (the actual starting dose must always be considered in the actual patient) Food Dose Reference Peanut 0,1 mg (39, 56–58) Milk 0,1 ml (12, 31, 43, 59, 60) Egg 1 mg (31, 61, 62) Cod 5 mg (42) Wheat 100 mg (Personal communication) Soy 1 mg (31, 63) Shrimp 5 mg (64)”
Background
World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines
Fiocchi, A., Brożek, J., Schunemann, H., Bahna, S., von Berg, A., Beyer, K., Bozzola, M., Bradsher, J., Compalati, E., Ebisawa, M., et al. (2010) · The World Allergy Organization Journal · doi:10.1097/wox.0b013e3181defeb9 · Cited by 602
The natural history of egg allergy
Savage, J. H., Matsui, E. C., Skripak, J. M., & Wood, R. A. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2007.09.040 · Cited by 591
Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function
Hertzler, S. R., Lieblein-Boff, J. C., Weiler, M., & Allgeier, C. (2020) · Nutrients · doi:10.3390/nu12123704 · Cited by 594
The epidemiology of food allergy in Europe: a systematic review and meta‐analysis
Nwaru, B. I., Hickstein, L., Panesar, S. S., Muraro, A. M., Werfel, T., Cardona, V., Dubois, A. E. J., Halken, S., Hoffmann‐Sommergruber, K., Poulsen, L. K., et al. (2013) · Allergy · doi:10.1111/all.12305 · Cited by 513
Immunologic changes in children with egg allergy ingesting extensively heated egg
Lemon-Mulé, H., Sampson, H. A., Sicherer, S. H., Shreffler, W. G., Noone, S. A., & Nowak-Wegrzyn, A. H. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.09.007 · Cited by 476
The natural history of milk allergy in an observational cohort
Wood, R. A., Sicherer, S. H., Vickery, B. P., Jones, S. M., Liu, A. H., Fleischer, D. M., Henning, A. K., Mayer, L., Burks, A. W., Grishin, A. V., et al. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.10.060 · Cited by 475
The Natural History of Food Allergy
Savage, J. H., Sicherer, S. H., & Wood, R. A. (2016) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2015.11.024 · Cited by 399
The prevalence of food hypersensitivity in an unselected population of children and adults
Østerballe, M., Hansen, T. K., Mortz, C. G., Høst, A., & Bindslev‐Jensen, C. (2005) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2005.00251.x · Cited by 383
Prediction of tolerance on the basis of quantification of egg white-specific IgE antibodies in children with egg allergy
Boyano‐Martínez, T., García‐Ara, C., Díaz‐Pena, J. M., & Martín‐Esteban, M. (2002) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2002.126081 · Cited by 329
Food Allergy
Savage, J. H., & Johns, C. B. (2014) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2014.09.004 · Cited by 295
The Natural History of Food Allergy
Wood, R. A. (2003) · PEDIATRICS · doi:10.1542/peds.111.s3.1631 · Cited by 283
The natural history of egg allergy in an observational cohort
Sicherer, S. H., Wood, R. A., Vickery, B. P., Jones, S. M., Liu, A. H., Fleischer, D. M., Dawson, P. M., Mayer, L., Burks, A. W., Grishin, A. V., et al. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.12.1041 · Cited by 281
Establishment of Reference Doses for residues of allergenic foods: Report of the VITAL Expert Panel
Taylor, S. L., Baumert, J. L., Kruizinga, A. G., Remington, B. C., Crevel, R., Brooke‐Taylor, S., Allen, K. J., & Houben, G. F. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.10.032 · Cited by 276
Food allergy: a practice parameter.
Chapman, J., Bernstein, I., Lee, R. E., Oppenheimer, J., Nicklas, R., Portnoy, J., Sicherer, S., Schuller, D., Spector, S., Khan, D. A., et al. (2006) · Annals of Allergy, Asthma & Immunology · doi:10.1016/s1081-1206(10)60926-x · Cited by 269
Food allergy
Sicherer, S. H. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09831-8 · Cited by 262
Frequency of food allergy in Europe: An updated systematic review and meta‐analysis
Spolidoro, G., Amera, Y. T., Ali, M. M., Nyassi, S., Lisik, D., Ioannidou, A., Rovner, G., Khaleva, E., Venter, C., van Ree, R., et al. (2022) · Allergy. European Journal of Allergy and Clinical Immunology · doi:10.1111/all.15560 · Cited by 244
Is delivery by cesarean section a risk factor for food allergy?
Eggesbø, M. Å., Botten, G., Stigum, H., Nafstad, P. H. J., & Magnus, P. M. (2003) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2003.1610 · Cited by 255
Utility of ovomucoid-specific IgE concentrations in predicting symptomatic egg allergy
Ando, H., Movérare, R., Kondo, Y., Tsuge, I., Tanaka, A., Borres, M. P., & Urisu, A. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.06.016 · Cited by 253
Incidence of parentally reported and clinically diagnosed food hypersensitivity in the first year of life
Venter, C., Pereira, B., Grundy, J. D., Clayton, C. B., Roberts, G. C., Higgins, B., & Dean, T. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.12.1352 · Cited by 249
“Reasons for nonconsent/recruitment included lack of interest (56), moving from the island (12), stillbirths (6), missed opportunities to recruit (11), language issues ( 4 ), and antenatal complications (5).”
Background
Scientific Opinion on the evaluation of allergenic foods and food ingredients for labelling purposes
Products, E. P. O. D. (2014) · EFSA Journal · doi:10.2903/j.efsa.2014.3894 · Cited by 242
Food allergy: review, classification and diagnosis.
Cianferoni, A., & Spergel, J. (2009) · Allergology International · doi:10.2332/allergolint.09-rai-0138 · Cited by 217
Allergen reference doses for precautionary labeling (VITAL 2.0): Clinical implications
Allen, K. J., Remington, B. C., Baumert, J. L., Crevel, R., Houben, G. F., Brooke‐Taylor, S., Kruizinga, A. G., & Taylor, S. L. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.06.042 · Cited by 215
Recent advances in the understanding of egg allergens: basic, industrial, and clinical perspectives
Mine, Y., & Yang, M. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf8001153 · Cited by 196
Milk processing as a tool to reduce cow’s milk allergenicity: a mini-review
Bu, G., Luo, Y., Chen, F., Liu, K., & Zhu, T. (2013) · Dairy Science and Technology · doi:10.1007/s13594-013-0113-x · Cited by 188
“It has been estimated to affect around 1% to 2% of the adult population and 5% to 8% of children below the age of 3 (Eggesbo et al. 2001; Halmerbauer et al. 2002; Helm and Burks 2000).”
Background
Current understanding of egg allergy
Caubet, J., & Wang, J. (2011) · The Pediatric clinics of North America · doi:10.1016/j.pcl.2011.02.014 · Cited by 175
Role of food allergy in atopic dermatitis
Werfel, T., & Breuer, K. (2004) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/00130832-200410000-00009 · Cited by 181
Long-term treatment with egg oral immunotherapy enhances sustained unresponsiveness that persists after cessation of therapy
Jones, S. M., Burks, A. W., Keet, C. A., Vickery, B. P., Scurlock, A. M., Wood, R. A., Liu, A. H., Sicherer, S. H., Henning, A. K., Lindblad, R., et al. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.12.1316 · Cited by 179
Adverse reactions to foods.
Nowak-Węgrzyn, A., & Sampson, H. (2006) · The Medical clinics of North America · doi:10.1016/j.mcna.2005.08.012 · Cited by 148
Incidence and natural history of hen's egg allergy in the first 2 years of life—the EuroPrevall birth cohort study
Xepapadaki, P. V., Fiocchi, A. G., Grabenhenrich, L., Roberts, G. C., Grimshaw, K. E. C., Fiandor, A. M., Larco, J. I., SIGURDARDOTTIR, S. T., Clausen, M. V., Papadopoulos, N. G., et al. (2015) · Allergy · doi:10.1111/all.12801 · Cited by 175
Clinical practice. Food allergy.
Lack, G. (2008) · New England Journal of Medicine · doi:10.1056/nejmcp0800871 · Cited by 174
Food allergy and food sensitization in early childhood: results from the DARC cohort
Eller, E., Kjær, H. F., Høst, A., Andersen, K. E., & Bindslev‐Jensen, C. (2009) · Allergy · doi:10.1111/j.1398-9995.2009.01952.x · Cited by 168
“At 18 month of age, 2.4% of the children had documented egg allergy, decreasing to 1.9% at 36 months, in accordance with the finding of Eggesbo (24) (1.6% at 2½ years of age) and Venter (7) (1.8% at 1 year; 1.0% at 3 years).”
BackgroundResultInfluential
Can we determine a threshold level for allergenic foods by statistical analysis of published data in the literature?
Bindslev‐Jensen, C., Briggs, D., & Østerballe, M. (2002) · Allergy · doi:10.1034/j.1398-9995.2002.23797.x · Cited by 161
Clinical Spectrum of Food Allergies: a Comprehensive Review
Ho, M., Wong, W. H. S., & Chang, C. C.-C. (2012) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-012-8339-6 · Cited by 164
“Most egg allergies are IgE mediated [44].”
Prevalence estimates of eight big food allergies in Europe: Updated systematic review and meta‐analysis
Spolidoro, G. C. I., Ali, M. M., Amera, Y. T., Nyassi, S., Lisik, D., Ioannidou, A., Rovner, G., Khaleva, E., Venter, C., van Ree, R., et al. (2023) · Allergy · doi:10.1111/all.15801 · Cited by 157
Epidemiology of Food Allergy
Venter, C., & Arshad, S. H. (2011) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2011.02.011 · Cited by 149
Effect of heat treatment on the potential allergenicity and conformational structure of egg allergen ovotransferrin
Tong, P., Gao, J., Chen, H., Li, X., Zhang, Y., Jian, S., Wichers, H. J., Wu, Z., Yang, A., & Liu, F. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2011.08.084 · Cited by 136
British Society for Allergy and Clinical Immunology guidelines for the management of egg allergy
Clark, A. T., Skypala, I. J., Leech, S. C., Ewan, P. W., Dugué, P., Brathwaite, N., Huber, P. A. J., & Nasser, S. M. (2010) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2010.03557.x · Cited by 134
Nutrient intake among two-year-old children on cows' milk-restricted diets
Henriksen, C., Eggesbø, M. Å., Halvorsen, R., & Botten, G. (2000) · Acta Paediatrica · doi:10.1111/j.1651-2227.2000.tb01328.x · Cited by 129
Oral Immunotherapy for Egg Allergy: A Double-Blind Placebo-Controlled Study, with Postdesensitization Follow-Up
Caminiti, L., Pajno, G. B., Crisafulli, G., Chiera, F., Collura, M., Panasci, G., Ruggeri, P., Guglielmo, F., & Passalacqua, G. (2015) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2015.01.017 · Cited by 124
The prevalence of CMA/CMPI in young children: the validity of parentally perceived reactions in a population‐based study
Eggesbø, M. Å., Botten, G., Halvorsen, R., & Magnus, P. M. (2001) · Allergy · doi:10.1034/j.1398-9995.2001.056005393.x · Cited by 122
Significance of ovomucoid- and ovalbumin-specific IgE/IgG4 ratios in egg allergy
Caubet, J., Bencharitiwong, R., Moshier, E. L., Godbold, J., Sampson, H. A., & Nowak-Wegrzyn, A. H. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.11.053 · Cited by 121
The Prevalence of food hypersensitivity in young adults
Osterballe, M., Mortz, C. G., Hansen, T. K., Andersen, K. E., & Bindslev‐Jensen, C. (2009) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2008.00842.x · Cited by 121
Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy
Sicherer, S. H., Wood, R. A., Stablein, D. M., Burks, A. W., Liu, A. H., Jones, S. M., Fleischer, D. M., Leung, D. Y. M., Grishin, A. V., Mayer, L., et al. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.02.038 · Cited by 108
Food allergy: an overview.
Kagan, R. (2003) · Environmental Health Perspectives · doi:10.1289/ehp.5702 · Cited by 131
“The prevalence of egg allergy is estimated at 1.6‐2.6% of the general pediatric population but is significantly higher among individuals with atopic dermatitis and other collateral atopic conditions (Danneus et al. 1977; Eggesbo et al. 2001 ).”
BackgroundInfluential
Approaches to establish thresholds for major food allergens and for gluten in food.
Buchanan, R., Dennis, S., Gendel, S., Acheson, D., Assimon, S. A., Beru, N., Bolger, P., Carlson, D., Carvajal, R., Copp, C., et al. (2008) · Journal of Food Protection · doi:10.4315/0362-028x-71.5.1043 · Cited by 100
Current issues with influenza vaccination in egg allergy
Zeiger, R. S. (2002) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2002.129372 · Cited by 101
Ovomucoid (Gal d 1) specific IgE detected by microarray system predict tolerability to boiled hen's egg and an increased risk to progress to multiple environmental allergen sensitisation
Alessandri, C., Zennaro, D., Scala, E., Ferrara, R., Bernardi, M. L., Santoro, M., Palazzo, P., & Mari, A. (2012) · Clinical and Experimental Allergy · doi:10.1111/j.1365-2222.2011.03915.x · Cited by 65
Skin prick test to egg white provides additional diagnostic utility to serum egg white–specific IgE antibody concentration in children
Knight, A. K., Shreffler, W. G., Sampson, H. A., Sicherer, S. H., Noone, S. A., Mofidi, S., & Nowak-Wegrzyn, A. H. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.12.1304 · Cited by 100
State of the art and new horizons in the diagnosis and management of egg allergy
Benhamou, A., Caubet, J., Eigenmann, P., Grzyn, A. N., Marcos, C., Reche, M., & Urisu, A. (2010) · Allergy. European Journal of Allergy and Clinical Immunology · doi:10.1111/j.1398-9995.2009.02251.x · Cited by 100
Egg-allergic patients can be safely vaccinated against influenza
Roches, A. D., Paradis, L. P., Gagnon, R., Lemire, C., Bégin, P., Carr, S., Chan, E. S., Paradis, J., Frenette, L., Ouakki, M., et al. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.07.046 · Cited by 94
“Egg allergy is the second most frequent food allergy and affects 1% to 2% of young children.(4) While most patients will eventually develop tolerance to eggs, it will still be present in more than 60% by 6 years of age.”
Background
Food Allergy Overview in Children
Ramesh, S. (2008) · Clinical reviews in allergy and immunology · doi:10.1007/s12016-007-8034-1 · Cited by 102
“A population-based prospective study reported the point prevalence of egg allergy to be 1.6% as confirmed by oral challenges [ 55 ].”
BackgroundInfluential
Effect of Covalent Interaction with Chlorogenic Acid on the Allergenic Capacity of Ovalbumin
Lu, Y., Li, S., Xu, H., Zhang, T., Lin, X. H., & Wu, X. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b03410 · Cited by 92
The Natural History of Food Allergy
Wood, R. A. (2013) · doi:10.1002/9781118744185.ch37 · Cited by 91
Correlation between specific immunoglobulin E levels and the severity of reactions in egg allergic patients
Benhamou, A., Zamora, S., & Eigenmann, P. (2008) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2007.00602.x · Cited by 91
Safety of Influenza Vaccine Administration in Egg-Allergic Patients
Chung, E., Huang, L., & Schneider, L. C. (2010) · PEDIATRICS · doi:10.1542/peds.2009-2512 · Cited by 85
Influenza vaccines: Evaluation of the safety profile
Trombetta, C. M., Gianchecchi, E., & Montomoli, E. (2018) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2017.1423153 · Cited by 88
The Influence of the Time and Temperature of Heat Treatment on the Allergenicity of Egg White Proteins
Shin, M., Han, Y., & Ahn, K. (2013) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2013.5.2.96 · Cited by 82
“6% of children.(3,4) Egg allergy has been shown to be the most common food allergy in children with atopic dermatitis.”
Background
Ovomucoid Is Not Superior to Egg White Testing in Predicting Tolerance to Baked Egg
Bartnikas, L. M., Sheehan, W. J., Larabee, K. S., Petty, C. R., Schneider, L. C., & Phipatanakul, W. (2013) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2013.04.002 · Cited by 81
Position document: IgE-mediated allergy to egg protein
Martorell, A., Alonso, E., Boné, J., Echeverría, L., López, M. C., Martín, F., Nevot, S., & Plaza, A. M. (2013) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2013.03.005 · Cited by 79
Early sustained unresponsiveness after short‐course egg oral immunotherapy: a randomized controlled study in egg‐allergic children
Escudero, C., del Río, P. R., Sánchez-García, S., Pérez‐Rangel, I., Pérez‐Farinós, N., García‐Fernández, C., & Ibáñez, M. D. (2015) · Clinical & Experimental Allergy · doi:10.1111/cea.12604 · Cited by 76
Molecular diagnosis of egg allergy
Caubet, J., Kondo, Y., Urisu, A., & Nowak-Wegrzyn, A. H. (2011) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e3283464d1b · Cited by 75
CD4 T cells activated in the mesenteric lymph node mediate gastrointestinal food allergy in mice
Knight, A. K., Blázquez, A.-B., Zhang, S., Mayer, L., Sampson, H. A., & Berin, M. C. (2007) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00323.2007 · Cited by 75
Cracking the egg: An insight into egg hypersensitivity
Dhanapala, P., Silva, C. D., Doran, T. J., & Suphioglu, C. (2015) · Molecular Immunology · doi:10.1016/j.molimm.2015.04.016 · Cited by 78
BSACI 2021 guideline for the management of egg allergy
Leech, S. C., Ewan, P. W., Skypala, I. J., Brathwaite, N., Erlewyn‐Lajeunesse, M., Heath, S., Ball, H., James, P., Murphy, K., & Clark, A. T. (2021) · Clinical & Experimental Allergy · doi:10.1111/cea.14009 · Cited by 71
Prevalence of self-reported food allergy in Hong Kong children and teens--a population survey.
Ho, M., Lee, S. L., Wong, W. H. S., Ip, P., & Lau, Y. (2012) · PubMed · Cited by 71
Occurrence of parent‐reported food hypersensitivities and food allergies among children aged 1–4 yr
Pyrhönen, K., Näyhä, S., Kaila, M., Hiltunen, L. A., & Läärä, E. (2009) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2008.00792.x · Cited by 70
Pasteurisation of liquid whole egg: Optimal heat treatments in relation to its functional, nutritional and allergenic properties
Lechevalier-Datin, V., Guérin‐Dubiard, C., Anton, M., Beaumal, V., Briand, E. D., Gillard, A., Gouar, Y. L., Musikaphun, N., Tanguy, G., Pasco, M., et al. (2016) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2016.10.007 · Cited by 70
Safety of live attenuated influenza vaccine in atopic children with egg allergy
Turner, P., Southern, J., Andrews, N. J., Miller, E., Erlewyn-Lajeunesse, M., Doyle, C. A., Toit, G. D., Erlewyn-Lajeunesse, M., Fitzsimons, R., Heath, P. T., et al. (2015) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.12.1925 · Cited by 68
Recommendations for the administration of influenza vaccine in children allergic to egg
Erlewyn‐Lajeunesse, M., Brathwaite, N., Lucas, J. S., & Warner, J. O. (2009) · BMJ · doi:10.1136/bmj.b3680 · Cited by 67
Food Allergy in Ghanaian Schoolchildren: Data on Sensitization and Reported Food Allergy
Obeng, B. B., Amoah, A. S., Larbi, I. A., Yazdanbakhsh, M., van Ree, R., Boakye, D. A., & Hartgers, F. C. (2010) · International Archives of Allergy and Immunology · doi:10.1159/000318704 · Cited by 67
Natural history of food allergy in infants and children in Israel.
Aaronov, D., Tasher, D., Levine, A., Somekh, E., Serour, F., & Dalal, I. (2008) · Annals of Allergy, Asthma & Immunology · doi:10.1016/s1081-1206(10)60228-1 · Cited by 60
Asthma Symptoms and Bronchial Reactivity in School Children Sensitized to Food Allergens in Infancy
Priftis, K. Ν., Mermiri, D., Papadopoulou, A., Papadopoulos, M., Fretzayas, A., & Lagona, E. (2008) · Journal of Asthma · doi:10.1080/02770900802032941 · Cited by 59
Untargeted Metabolomic Profiling Reveals Changes in Gut Microbiota and Mechanisms of Its Regulation of Allergy in OVA-Sensitive BALB/c Mice
Xu, J., Ye, Y., Ji, J., Sun, J., Wang, J.-S., & Sun, X. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c07482 · Cited by 58
Is it possible to make a diagnosis of raw, heated, and baked egg allergy in children using cutoffs? A systematic review
Calvani, M., Arasi, S., Bianchi, A., Caimmi, D. P., Cuomo, B., Dondi, A., Indirli, G. C., Grutta, S. L., Panetta, V., & Verga, M. C. (2015) · Pediatric Allergy and Immunology · doi:10.1111/pai.12432 · Cited by 58
Development and Validation of an Enzyme-Linked Immunosorbent Assay (ELISA) for Quantification of Lysozyme in Cheese
Schneider, N., Weigel, I., Werkmeister, K., & Pischetsrieder, M. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9025019 · Cited by 56
Analysis of Food Allergen Structures and Development of Foods for Allergic Patients
Tanabe, S. (2008) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.70708 · Cited by 56
Prevalence of food allergy in infants and pre-schoolers in Brazil
Gonçalves, L., Guimarães, T. C. P., Silva, R. M., Cheik, M. F. A., de Nápolis, A. C. R., Silva, G., & Segundo, G. R. S. (2016) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2016.04.009 · Cited by 54
Restricted diets in children with reactions to milk and egg perceived by their parents
Eggesbø, M. Å., Botten, G., & Stigum, H. (2001) · The Journal of Pediatrics · doi:10.1067/mpd.2001.117067 · Cited by 54
Debates in allergy medicine: baked milk and egg ingestion accelerates resolution of milk and egg allergy
Leonard, S. A. (2016) · World Allergy Organization Journal · doi:10.1186/s40413-015-0089-5 · Cited by 53
“9 % of infants [1–3, 6, 7].”
Immunomodulatory Effects of Egg White Enzymatic Hydrolysates Containing Immunodominant Epitopes in a BALB/c Mouse Model of Egg Allergy
Yang, M., Yang, C., Nau, F., Pasco, M., Juneja, L. R., Okubo, T., & Mine, Y. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf803372b · Cited by 52
Efficacy and safety of high-dose rush oral immunotherapy in persistent egg allergic children
Pérez‐Rangel, I., del Río, P. R., Escudero, C., Sánchez-García, S., Sánchez-Hernández, J. J., & Ibáñez, M. D. (2017) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2016.11.023 · Cited by 51
“30 The secondary objectiveswere (1) to evaluate the safety; (2) to assess potential individual, single predictors for development of more than 2 AEs; and (3) to detect immunologic changes linked to the clinical parameters.”
Background
Patterns of immunoglobulin G responses to egg and peanut allergens are distinct: ovalbumin‐specific immunoglobulin responses are ubiquitous, but peanut‐specific immunoglobulin responses are up‐regulated in peanut allergy
Tay, S. S., Clark, A. T., Deighton, J., King, Y., & Ewan, P. W. (2007) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2007.02802.x · Cited by 48
Effective therapy of childhood atopic dermatitis allays food allergy concerns
Thompson, M. M., & Hanifin, J. M. (2005) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2005.04.065 · Cited by 48
A retrospective analysis of allergic reaction severities and minimal eliciting doses for peanut, milk, egg, and soy oral food challenges
Zhu, J., Pouillot, R., Kwegyir-Afful, E. K., Luccioli, S., & Gendel, S. M. (2015) · Food and Chemical Toxicology · doi:10.1016/j.fct.2015.02.023 · Cited by 47
Caffeic acid-assisted cross-linking catalyzed by polyphenol oxidase decreases the allergenicity of ovalbumin in a Balb/c mouse model
Tong, P., Chen, S., Gao, J., Li, X., Wu, Z., Yang, A., Yuan, J., & Chen, H. (2017) · Food and Chemical Toxicology · doi:10.1016/j.fct.2017.11.026 · Cited by 47
Comprehensive Review of Current Knowledge on Egg Oral Immunotherapy.
Ibáñez, Escudero, C., Sánchez-García, S., & del Río, P. R. (2015) · PubMed · Cited by 46
Development of a monoclonal antibody-based sandwich ELISA for the detection of ovalbumin in foods
Peng, J., Xu, M. J., Deng, X., Zhu, J., Kuang, H., & Xu, C. (2012) · Food and Agricultural Immunology · doi:10.1080/09540105.2012.716398 · Cited by 46
“However, egg is one of the most frequent causes of food allergy, especially in children (Eggesbo, Botten, Halvorsen, & Magnus, 2001 ).”
Background
The Influence of the Presence of Wheat Flour on the Antigenic Activities of Egg White Proteins
Shin, M., Lee, J., Ahn, K., Lee, S. I., & Han, Y. (2012) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2013.5.1.42 · Cited by 45
“6% of children.(3,4) Egg has been shown to be the most common food allergy in children with atopic dermatitis, and approximately two-thirds of children with atopic dermatitis are reactive to egg white (EW).”
Background
Symposium: Pediatric Food Allergy
Sicherer, S. H., Muñoz‐Furlong, A., Murphy, R. J. C., Wood, R. A., & Sampson, H. A. (2003) · PEDIATRICS · doi:10.1542/peds.111.s3.1591 · Cited by 45
Safe administration of an inactivated virosomal adjuvanted influenza vaccine in asthmatic children with egg allergy
Esposito, S., Gasparini, C., Martelli, A. M., Zenga, A., Tremolati, E., Varin, E., Marseglia, G. L., Fiocchi, A. G., & Principi, N. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.06.095 · Cited by 45
Criteria for identifying allergenic foods of public health importance
Björkstén, B., Crevel, R., Hischenhuber, C., Løvik, M., Samuels, F., Ströbel, S., Taylor, S., Wal, J. M., & Ward, R. (2008) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2008.01.002 · Cited by 44
“IgE-mediated mechanism Several clinical studies X (b) Confirmed by DBPCFC Several clinical and population studies X Prevalence 2.6% ± 1% at 2 years ( Eggesbo et al., 2001 )X Severity Severity increase >3.33 mg (Hefle et al., 2003 )X Potency Oral challenge X (a)”
BackgroundInfluential
Food Production and Processing Considerations of Allergenic Food Ingredients: A Review
Alvarez, P. A., & Boye, J. I. (2011) · Journal of Allergy · doi:10.1155/2012/746125 · Cited by 41
“[143] M.”
The panel of egg allergens, Gal d 1-Gal d 5: Their improved purification and characterization
Jacobsen, B., Hoffmann‐Sommergruber, K., Have, T. T., Foss, N., Briza, P., Oberhuber, C., Radauer, C., Alessandri, S., Knulst, A. C., Fernández‐Rivas, M., et al. (2008) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200700414 · Cited by 41
The Prevalence and Natural History of Food Allergy
Kattan, J. D. (2016) · Current Allergy and Asthma Reports · doi:10.1007/s11882-016-0627-4 · Cited by 39

Egg Allergy in US Children
Williams, P. V. (2021) · PEDIATRICS · doi:10.1542/peds.2021-053843bb · Cited by 1
Egg allergy – where we stand in 2022?
Bocşan, I., Muntean, I. A., & Feketea, G. M. (2022) · Alergologia · doi:10.26416/aler.6.4.2022.7401
Häufigkeit und Verlauf der Hühnereiallergie bei Kleinkindern in Deutschland: die EuroPrevall-Geburtskohortenstudie
Eckers, N., Grabenhenrich, L., D.McBride, Gough, H., Reich, A., Rosenfeld, L., Niggemann, B., Siegert, S., Aksünger, Ö., Wjst, M., et al. (2015) · Allergologie · doi:10.5414/alx01781 · Cited by 4
The Natural History and Clinical Predictors of Egg Allergy in the First 2 Years of Life: A Prospective, Population-Based Cohort Study
Sood, A., & Jones, S. M. (2014) · PEDIATRICS · doi:10.1542/peds.2014-1817ee · Cited by 2
Incidence and natural history of hen's egg allergy in the first 2 years of life—the EuroPrevall birth cohort study
Xepapadaki, P. V., Fiocchi, A. G., Grabenhenrich, L., Roberts, G. C., Grimshaw, K. E. C., Fiandor, A. M., Larco, J. I., SIGURDARDOTTIR, S. T., Clausen, M. V., Papadopoulos, N. G., et al. (2015) · Allergy · doi:10.1111/all.12801 · Cited by 175

Authors: Eggesbø, M., Botten, G., Halvorsen, R., & Magnus, P.
Affiliations: Norwegian Institute of Public Health (NO)
University of Oslo (NO)
Oslo University Hospital (NO)
Corresponding author: Eggesbø, M.
ORCID: Eggesbø, M.
Magnus, P.
Venue: Allergy
Publisher: Wiley
Published: 2001-05
Volume: 56
Issue: 5
Pages: 403-411
ISSN: 0105-4538 (ISSN-L)
1398-9995
DOI: 10.1034/j.1398-9995.2001.056005403.x
OpenAlex: W1983108554
Cited by: 290
References: 37
Citations by year: 2026: 5 · 2025: 5 · 2024: 5 · 2023: 4 · 2022: 9 · 2021: 7 · 2020: 5 · 2019: 5 · 2018: 10 · 2017: 7 · 2016: 21 · 2015: 25 · 2014: 17 · 2013: 22 · 2012: 18
FWCI: 3.29
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 259 d)
Locations: Allergy (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
Health Sciences › Medicine › Gastroenterology › Eosinophilic Esophagitis
Health Sciences › Medicine › Pharmacology (medical) › Drug-Induced Adverse Reactions
Keywords: egg allergy, prevalence, young children, food allergy, IgE-mediated reactions, positive predictive value, cumulative incidence, double-blind placebo-controlled food challenge, skin prick test
MeSH terms: Child, Preschool, Double-Blind Method, Eggs, Female, Food Hypersensitivity, Humans, Intradermal Tests, Male, Norway, Population Surveillance, Surveys and Questionnaires, Socioeconomic Factors, Cohort Studies, Incidence, Prevalence, Age Distribution

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The prevalence of allergy to egg: A population-based study in young children

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